3,6′-dithiothalidomide improves experimental stroke outcome by suppressing neuroinflammation

Anti-TNF Monoclonal Antibodies in Inflammatory Bowel Disease: Pharmacokinetics-Based Dosing Paradigms

(2012) I Ordás et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Inflammatory Cytokines in Experimental and Human Stroke

(2012) Kate Lykke Lambertsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Early intervention with a small molecule inhibitor for tumor nefosis factor-α prevents cognitive deficits in a triple transgenic mouse model of Alzheimer’s disease

(2012) S Prasad Gabbita et al.   Journal of Neuroinflammation

TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation

(2012) Karim Belarbi et al.   Journal of Neuroinflammation

Tumor necrosis factor-α synthesis inhibitor 3,6′-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer’s disease

(2012) David Tweedie et al.   Journal of Neuroinflammation

Blood-Brain Barrier Permeability Is Increased After Acute Adult Stroke But Not Neonatal Stroke in the Rat

(2012) D. Fernandez-Lopez et al.   JOURNAL OF NEUROSCIENCE

Systematic Review and Meta-Analysis of the Efficacy and Safety of Existing TNF Blocking Agents in Treatment of Rheumatoid Arthritis

(2012) Kalle J. Aaltonen et al.   PLoS One

Endonuclease VIII-like 1 (NEIL1) promotes short-term spatial memory retention and protects from ischemic stroke-induced brain dysfunction and death in mice

(2012) C. Canugovi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heart Disease and Stroke Statistics—2012 Update

(2011) et al.   CIRCULATION

The evolving experience with therapeutic TNF inhibition in sepsis: considering the potential influence of risk of death

(2011) Ping Qiu et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Genetic deletion of TNF receptor suppresses excitatory synaptic transmission via reducing AMPA receptor synaptic localization in cortical neurons

(2011) Ping He et al.   FASEB JOURNAL

Tumor necrosis factor-α synthesis inhibitor, 3,6′-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice

(2011) Renana Baratz et al.   JOURNAL OF NEUROCHEMISTRY

Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro

(2011) Fuyuko Takata et al.   Journal of Neuroinflammation

Anti-TNF therapy in the injured spinal cord

(2010) Emanuela Esposito et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Inflammation and brain injury: Acute cerebral ischaemia, peripheral and central inflammation

(2009) A. Denes et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroinflammation and Neuroprotective Strategies in Acute Ischaemic Stroke - from bench to bedside

(2009) Imtiaz Shah et al.   CURRENT MOLECULAR MEDICINE

A cellular model of inflammation for identifying TNF-α synthesis inhibitors

(2009) David Tweedie et al.   JOURNAL OF NEUROSCIENCE METHODS

Leukocyte Recruitment and Ischemic Brain Injury

(2009) Gokhan Yilmaz et al.   NEUROMOLECULAR MEDICINE

Thalidomide inhibition of vascular remodeling and inflammatory reactivity in the quinolinic acid–injected rat striatum

(2009) J.K. Ryu et al.   NEUROSCIENCE

Inflammatory Cytokines in Acute Ischemic Stroke

(2008) Antonino Tuttolomondo et al.   CURRENT PHARMACEUTICAL DESIGN

Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia

(2008) Wenlan Liu et al.   JOURNAL OF NEUROCHEMISTRY

Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase

(2008) M. O. Breckwoldt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke

(2008) Anna Rosell et al.   STROKE

Targeting TNF-α receptors for neurotherapeutics

(2008) Wayne Chadwick et al.   TRENDS IN NEUROSCIENCES