HIV-1 Viral Protein R Activates NLRP3 Inflammasome in Microglia: implications for HIV-1 Associated Neuroinflammation

Chronic systemic IL-1β exacerbates central neuroinflammation independently of the blood–brain barrier integrity

(2015) Verónica Murta et al.   JOURNAL OF NEUROIMMUNOLOGY

Use of the Open Field Maze to Measure Locomotor and Anxiety-like Behavior in Mice

(2015) Michael L. Seibenhener et al.   Jove-Journal of Visualized Experiments

Spinal cord toxoplasmosis in human immunodeficiency virus infection/acquired immunodeficiency syndrome

(2015) Concepción García-García et al.   Infectious Diseases

Differential Survival for Men and Women with HIV/AIDS-Related Neurologic Diagnoses

(2015) Martha L. Carvour et al.   PLoS One

Vpr Overcomes Macrophage-Specific Restriction of HIV-1 Env Expression and Virion Production

(2014) Michael Mashiba et al.   Cell Host & Microbe

THP-1 cell line: An in vitro cell model for immune modulation approach

(2014) Wasaporn Chanput et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

HIV-1 Infection Induces Interleukin-1β Production via TLR8 Protein-dependent and NLRP3 Inflammasome Mechanisms in Human Monocytes

(2014) Haitao Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Controversies in HIV-associated neurocognitive disorders

(2014) Sam Nightingale et al.   LANCET NEUROLOGY

Metabolomic profiling in multiple sclerosis: insights into biomarkers and pathogenesis

(2014) SN Reinke et al.   Multiple Sclerosis Journal

Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

(2014) John G Walsh et al.   Retrovirology

Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND)

(2014) Vasudev R Rao et al.   AIDS Research and Therapy

Altered cognitive-emotional behavior in early experimental autoimmune encephalitis – Cytokine and hormonal correlates

(2013) Shaona Acharjee et al.   BRAIN BEHAVIOR AND IMMUNITY

HIV-1 Induces the First Signal to Activate the NLRP3 Inflammasome in Monocyte-Derived Macrophages

(2013) Juan C. Hernandez et al.   INTERVIROLOGY

Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain

(2013) Geeta Ramesh et al.   MEDIATORS OF INFLAMMATION

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2013) Gilad Doitsh et al.   NATURE

HIV-1 Vpr Accelerates Viral Replication during Acute Infection by Exploitation of Proliferating CD4+ T Cells In Vivo

(2013) Kei Sato et al.   PLoS Pathogens

The extent of sequence complementarity correlates with the potency of cellular miRNA-mediated restriction of HIV-1

(2012) Laurent Houzet et al.   NUCLEIC ACIDS RESEARCH

Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment

(2011) Jarek Harezlak et al.   AIDS

Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner

(2011) B. Vigl et al.   BLOOD

Breaking down the barrier: The effects of HIV-1 on the blood–brain barrier

(2011) Marianne Strazza et al.   BRAIN RESEARCH

Involvement of the p53 and p73 transcription factors in neuroAIDS

(2011) Ruma Mukerjee et al.   CELL CYCLE

The inflammasome: in memory of Dr. Jurg Tschopp

(2011) M Dagenais et al.   CELL DEATH AND DIFFERENTIATION

Brain Tumor Microvesicles: Insights into Intercellular Communication in the Nervous System

(2011) Kristan E. van der Vos et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Current understanding of HIV-associated neurocognitive disorders pathogenesis

(2011) Patrick Gannon et al.   CURRENT OPINION IN NEUROLOGY

Extracellular HIV-1 Tat upregulates TNF-α dependent MCP-1/CCL2 production via activation of ERK1/2 pathway in rat hippocampal slice cultures: Inhibition by resveratrol, a polyphenolic phytostilbene

(2011) Eun Ok Lee et al.   EXPERIMENTAL NEUROLOGY

HIV-1 Tat Protein Promotes Neuronal Dysfunction through Disruption of MicroRNAs

(2011) J. Robert Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Delineating HIV-Associated Neurocognitive Disorders Using Transgenic Models: The Neuropathogenic Actions of Vpr

(2011) Christopher Power et al.   Journal of Neuroimmune Pharmacology

Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice

(2011) Mattia Maroso et al.   Neurotherapeutics

HIV-1 Accessory Protein Vpr: Relevance in the pathogenesis of HIV and potential for therapeutic intervention

(2011) Michael Kogan et al.   Retrovirology

Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence

(2011) Hong Na et al.   Retrovirology

Inflammasome activation and IL-1β and IL-18 processing during infection

(2011) Frank L. van de Veerdonk et al.   TRENDS IN IMMUNOLOGY

HIV-1 viral protein R causes peripheral nervous system injury associated with in vivo neuropathic pain

(2010) Shaona Acharjee et al.   FASEB JOURNAL

MicroRNA profiling reveals new aspects of HIV neurodegeneration: caspase-6 regulates astrocyte survival

(2010) Farshid Noorbakhsh et al.   FASEB JOURNAL

Molecular and Phylogenetic Analysis of HIV Type 1 vpr Sequences of South African Strains

(2009) Bizhan Romani et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Cutting Edge: TNF-  Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation

(2009) L. Franchi et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Activation of Inflammasomes Requires Intracellular Redistribution of the Apoptotic Speck-Like Protein Containing a Caspase Recruitment Domain

(2009) N. B. Bryan et al.   JOURNAL OF IMMUNOLOGY

Detection of microRNA Expression in Human Peripheral Blood Microvesicles

(2008) Melissa Piper Hunter et al.   PLoS One

Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases

(2007) Yong Xiao et al.   VIROLOGY