Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND)

Signaling Mechanism of HIV-1 gp120 and Virion-Induced IL-1  Release in Primary Human Macrophages

(2014) R. Cheung et al.   JOURNAL OF IMMUNOLOGY

HIV and Aging: Effects on the Central Nervous System

(2014) Silvia Cañizares et al.   SEMINARS IN NEUROLOGY

Drug use as a driver of HIV risks

(2014) Nabila El-Bassel et al.   Current Opinion in HIV and AIDS

Increased microglia activation in neurologically asymptomatic HIV-infected patients receiving effective ART

(2013) Lucy J. Garvey et al.   AIDS

Can high central nervous system penetrating antiretroviral regimens protect against the onset of HIV-associated neurocognitive disorders?

(2013) Matteo Vassallo et al.   AIDS

The cannabinoid CB2receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis

(2013) Hava Karsenty Avraham et al.   BRITISH JOURNAL OF PHARMACOLOGY

Astrocyte-Neuron Interaction at Tripartite Synapses

(2013) Alberto Pérez-Alvarez et al.   CURRENT DRUG TARGETS

Neuroprotective Activity of pDING in Response to HIV-1 Tat

(2013) Nune Darbinian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase

(2013) Ling Ye et al.   JOURNAL OF NEUROCHEMISTRY

Detection of anti-tat antibodies in CSF of individuals with HIV-associated neurocognitive disorders

(2013) M. Bachani et al.   JOURNAL OF NEUROVIROLOGY

Peripheral blood HIV DNA is associated with atrophy of cerebellar and subcortical gray matter

(2013) K. J. Kallianpur et al.   NEUROLOGY

Mechanisms of HIV Entry into the CNS: Increased Sensitivity of HIV Infected CD14+CD16+ Monocytes to CCL2 and Key Roles of CCR2, JAM-A, and ALCAM in Diapedesis

(2013) Dionna W. Williams et al.   PLoS One

CB2 Receptor Agonists Protect Human Dopaminergic Neurons against Damage from HIV-1 gp120

(2013) Shuxian Hu et al.   PLoS One

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

(2013) T. P. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence

(2013) Vasudev R Rao et al.   Retrovirology

Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice

(2012) Prasanta K. Dash et al.   AIDS

Astrocyte Calcium Signal and Gliotransmission in Human Brain Tissue

(2012) M. Navarrete et al.   CEREBRAL CORTEX

Multiple NF-κB Sites in HIV-1 Subtype C Long Terminal Repeat Confer Superior Magnitude of Transcription and Thereby the Enhanced Viral Predominance

(2012) Mahesh Bachu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: implications for HIV-associated neuroinflammation

(2012) Crystal Bethel-Brown et al.   Journal of Neuroinflammation

Human Immunodeficiency Virus Type 1 (HIV-1) Transactivator of Transcription through Its Intact Core and Cysteine-Rich Domains Inhibits Wnt/ -Catenin Signaling in Astrocytes: Relevance to HIV Neuropathogenesis

(2012) L. J. Henderson et al.   JOURNAL OF NEUROSCIENCE

Interferon-α Regulates Glutaminase 1 Promoter through STAT1 Phosphorylation: Relevance to HIV-1 Associated Neurocognitive Disorders

(2012) Lixia Zhao et al.   PLoS One

Synergistic Cooperation between Methamphetamine and HIV-1 gsp120 through the P13K/Akt Pathway Induces IL-6 but not IL-8 Expression in Astrocytes

(2012) Ankit Shah et al.   PLoS One

Platelet-Derived Growth Factor CC-Mediated Neuroprotection against HIV Tat Involves TRPC-Mediated Inactivation of GSK 3beta

(2012) Fuwang Peng et al.   PLoS One

Tissue inhibitor of metalloproteinases-1 protects human neurons from staurosporine and HIV-1-induced apoptosis: mechanisms and relevance to HIV-1-associated dementia

(2012) Ashutosh et al.   Cell Death & Disease

Global trends in molecular epidemiology of HIV-1 during 2000–2007

(2011) Joris Hemelaar et al.   AIDS

Inhibition of Anti-HIV MicroRNA Expression

(2011) Xu Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Does use of antiretroviral therapy regimens with high central nervous system penetration improve survival in HIV-infected adults?

(2011) H McManus et al.   HIV MEDICINE

Up-regulation of the Neuronal Nicotinic Receptor α7 by HIV Glycoprotein 120

(2011) Leomar Y. Ballester et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Tat Protein Promotes Neuronal Dysfunction through Disruption of MicroRNAs

(2011) J. Robert Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Raltegravir Treatment Intensification Does Not Alter Cerebrospinal Fluid HIV-1 Infection or Immunoactivation in Subjects on Suppressive Therapy

(2011) Viktor Dahl et al.   JOURNAL OF INFECTIOUS DISEASES

Methamphetamine and HIV-1 Tat Down Regulate β-catenin Signaling: Implications for Methampetamine Abuse and HIV-1 Co-morbidity

(2011) Amit Sharma et al.   Journal of Neuroimmune Pharmacology

A Failure to Normalize Biochemical and Metabolic Insults During Morphine Withdrawal Disrupts Synaptic Repair in Mice Transgenic for HIV-gp120

(2011) Veera Venkata Ratnam Bandaru et al.   Journal of Neuroimmune Pharmacology

Glutaminase Dysregulation in HIV-1-Infected Human Microglia Mediates Neurotoxicity: Relevant to HIV-1-Associated Neurocognitive Disorders

(2011) Y. Huang et al.   JOURNAL OF NEUROSCIENCE

Cocaine Hijacks  1 Receptor to Initiate Induction of Activated Leukocyte Cell Adhesion Molecule: Implication for Increased Monocyte Adhesion and Migration in the CNS

(2011) H. Yao et al.   JOURNAL OF NEUROSCIENCE

Human Immunodeficiency Virus Infection of Human Astrocytes Disrupts Blood-Brain Barrier Integrity by a Gap Junction-Dependent Mechanism

(2011) E. A. Eugenin et al.   JOURNAL OF NEUROSCIENCE

Programmed neuronal cell death induced by HIV-1 tat and methamphetamine

(2011) Li Qi et al.   MICROSCOPY RESEARCH AND TECHNIQUE

HIV-1 gp120 induces antioxidant response element-mediated expression in primary astrocytes: Role in HIV associated neurocognitive disorder

(2011) Pichili Vijaya Bhaskar Reddy et al.   NEUROCHEMISTRY INTERNATIONAL

Activation status of integrated stress response pathways in neurones and astrocytes of HIV-associated neurocognitive disorders (HAND) cortex

(2011) C. Akay et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

A Growth Factor Attenuates HIV-1 Tat and Morphine Induced Damage to Human Neurons: Implication in HIV/AIDS-Drug Abuse Cases

(2011) Shaily Malik et al.   PLoS One

Interactive Comorbidity between Opioid Drug Abuse and HIV-1 Tat

(2010) Sylvia Fitting et al.   AMERICAN JOURNAL OF PATHOLOGY

Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders

(2010) Yeon-Joo Kang et al.   ANNALS OF NEUROLOGY

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

Differential Induction of Interleukin-10 in Monocytes by HIV-1 Clade B and Clade C Tat Proteins

(2010) Justine K. Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactive role of human immunodeficiency virus type 1 (HIV-1) clade-specific Tat protein and cocaine in blood-brain barrier dysfunction: Implications for HIV-1–associated neurocognitive disorder

(2010) Nimisha Gandhi et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

Neurodegeneration and the neurovascular unit

(2010) Berislav V Zlokovic   NATURE MEDICINE

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Neurocognitive impairment among HIV-positive individuals in Botswana: a pilot study

(2010) Kathy Lawler et al.   Journal of the International AIDS Society

Differential Regulation of Indoleamine-2,3-Dioxygenase (IDO) by HIV Type 1 Clade B and C Tat Protein

(2009) Thangavel Samikkannu et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Short Communication: Methamphetamine Treatment Increases in Vitro and in Vivo HIV Replication

(2009) Sima Shelly Toussi et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Differential Effects of HIV Type 1 Clade B and Clade C Tat Protein on Expression of Proinflammatory and Antiinflammatory Cytokines by Primary Monocytes

(2009) Nimisha Gandhi et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia

(2009) Melissa J. Churchill et al.   ANNALS OF NEUROLOGY

Extracellular HIV-1 Tat up-regulates expression of matrix metalloproteinase-9 via a MAPK-NF-κB dependent pathway in human astrocytes

(2009) Sung Mi Ju et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Increased Accumulation of Intraneuronal Amyloid β in HIV-Infected Patients

(2009) Cristian L. Achim et al.   Journal of Neuroimmune Pharmacology

Compartmentalized Human Immunodeficiency Virus Type 1 Originates from Long-Lived Cells in Some Subjects with HIV-1–Associated Dementia

(2009) Gretja Schnell et al.   PLoS Pathogens

Methamphetamine Enhances HIV Infection of Macrophages

(2008) Hao Liang et al.   AMERICAN JOURNAL OF PATHOLOGY

NMDA Receptor Activation by HIV-Tat Protein Is Clade Dependent

(2008) W. Li et al.   JOURNAL OF NEUROSCIENCE

HIV-1 Clade-Specific Differences in the Induction of Neuropathogenesis

(2008) V. R. Rao et al.   JOURNAL OF NEUROSCIENCE

Cell‐specific actions of HIV‐Tat and morphine on opioid receptor expression in glia

(2008) Jadwiga Turchan‐Cholewo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Mechanisms of minocycline-induced suppression of simian immunodeficiency virus encephalitis: inhibition of apoptosis signal-regulating kinase 1

(2008) Susan C Follstaedt et al.   JOURNAL OF NEUROVIROLOGY

Platelet-derived growth factor protects neurons against gp120-mediated toxicity

(2008) Fuwang Peng et al.   JOURNAL OF NEUROVIROLOGY

Decreased brain dopamine transporters are related to cognitive deficits in HIV patients with or without cocaine abuse

(2008) Linda Chang et al.   NEUROIMAGE

Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis

(2008) Zsolt Tallóczy et al.   PLoS Pathogens

Clade-specific differences in neurotoxicity of human immunodeficiency virus-1 B and C Tat of human neurons: significance of dicysteine C30C31 motif

(2007) Mamata Mishra et al.   ANNALS OF NEUROLOGY