Mitoferrin, Cellular and Mitochondrial Iron Homeostasis

Mitoferrin 2 deficiency prevents mitochondrial iron overload-induced endothelial injury and alleviates atherosclerosis

(2021) Dongchen Wang et al.   EXPERIMENTAL CELL RESEARCH

RNA m6A Demethylase ALKBH5 Protects Against Pancreatic Ductal Adenocarcinoma via Targeting Regulators of Iron Metabolism

(2021) Rui Huang et al.   Frontiers in Cell and Developmental Biology

The mitochondrial metal transporters mitoferrin1 and mitoferrin2 are required for liver regeneration and cell proliferation in mice

(2020) Alexandra Seguin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrion-mediated iron accumulation promotes carcinogenesis and Warburg effect through reactive oxygen species in osteosarcoma

(2020) Shuo Ni et al.   Cancer Cell International

Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence

(2020) Jana Key et al.   Cells

MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma

(2020) Lin Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Integrative proteomics reveals principles of dynamic phosphosignaling networks in human erythropoiesis

(2020) Özge Karayel et al.   Molecular Systems Biology

Altered Expression of Mitoferrin and Frataxin, Larger Labile Iron Pool and Greater Mitochondrial DNA Damage in the Skeletal Muscle of Older Adults

(2020) Anna Picca et al.   Cells

In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion

(2019) Roel Bijkerk et al.   Nucleic Acid Therapeutics

Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis

(2019) Nunziata Maio et al.   HAEMATOLOGICA

The PSIPRED Protein Analysis Workbench: 20 years on

(2019) Daniel W A Buchan et al.   NUCLEIC ACIDS RESEARCH

MiR-7-5p is a key factor that controls radioresistance via intracellular Fe2+ content in clinically relevant radioresistant cells

(2019) Kazuo Tomita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitoferrin-1 is required for brain energy metabolism and hippocampus-dependent memory

(2019) Lisa Baldauf et al.   NEUROSCIENCE LETTERS

Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically

(2018) Sonal Agrawal et al.   FREE RADICAL BIOLOGY AND MEDICINE

In vitroreconstitution, functional dissection, and mutational analysis of metal ion transport by mitoferrin-1

(2018) Eric T. Christenson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitoferrin-1 is Involved in the Progression of Alzheimer’s Disease Through Targeting Mitochondrial Iron Metabolism in a Caenorhabditis elegans Model of Alzheimer’s Disease

(2018) Jiatao Huang et al.   NEUROSCIENCE

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

(2018) Changfeng Li et al.   DEVELOPMENTAL CELL

Overexpression of Drosophila frataxin triggers cell death in an iron-dependent manner

(2017) Oliver Edenharter et al.   JOURNAL OF NEUROGENETICS

Oxidative stress and mitochondrial damage in the pathogenesis of ALS: New perspectives

(2017) F. Bozzo et al.   NEUROSCIENCE LETTERS

Alzheimer's Disease: From Mitochondrial Perturbations to Mitochondrial Medicine

(2016) Susana Cardoso et al.   BRAIN PATHOLOGY

Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis

(2016) Jialiang Huang et al.   DEVELOPMENTAL CELL

Mitochondrial control of cell bioenergetics in Parkinson’s disease

(2016) Raquel Requejo-Aguilar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Identification of SLC25A37 as a major depressive disorder risk gene

(2016) Yong-Xia Huo et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Mitoferrin modulates iron toxicity in a Drosophila model of Friedreich׳s ataxia

(2015) Juan A. Navarro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Depletion of mitoferrins leads to mitochondrial dysfunction and impairment of adipogenic differentiation in 3T3-L1 preadipocytes

(2015) Y.-C. Chen et al.   FREE RADICAL RESEARCH

Knocking down mitochondrial iron transporter (MIT) reprograms primary and secondary metabolism in rice plants

(2015) Gianpiero Vigani et al.   JOURNAL OF EXPERIMENTAL BOTANY

Erratum: Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

(2015) H Dolatshad et al.   LEUKEMIA

Three conserved histidine residues contribute to mitochondrial iron transport through mitoferrins

(2014) Xavier Brazzolotto et al.   BIOCHEMICAL JOURNAL

The impact of microRNA expression on cellular proliferation

(2014) Divya Lenkala et al.   HUMAN GENETICS

Assessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing

(2013) Zhaojun Zhang et al.   BMC GENOMICS

Review: Iron metabolism and the role of iron in neurodegenerative disorders

(2013) M. Hadzhieva et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Mitochondrial iron transport and homeostasis in plants

(2013) Anshika Jain et al.   Frontiers in Plant Science

Cellular and mitochondrial iron homeostasis in vertebrates

(2012) Caiyong Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo

(2012) B B Hyde et al.   CELL DEATH AND DIFFERENTIATION

Mitoferrin-2-dependent Mitochondrial Iron Uptake Sensitizes Human Head and Neck Squamous Carcinoma Cells to Photodynamic Therapy

(2012) Hsin-I Hung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Mayhem: The Mitochondrion as a Modulator of Iron Metabolism and Its Role in Disease

(2011) Michael Li-Hsuan Huang et al.   ANTIOXIDANTS & REDOX SIGNALING

Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria

(2011) M.-B. Troadec et al.   BLOOD

Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury

(2011) Edouard I. Azzam et al.   CANCER LETTERS

Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria

(2011) Yongming Wang et al.   EXPERIMENTAL HEMATOLOGY

Identification of Distal cis-Regulatory Elements at Mouse Mitoferrin Loci Using Zebrafish Transgenesis

(2011) J. D. Amigo et al.   MOLECULAR AND CELLULAR BIOLOGY

The rice mitochondrial iron transporter is essential for plant growth

(2011) Khurram Bashir et al.   Nature Communications

Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis

(2010) W. Chen et al.   BLOOD

Drosophila mitoferrin is essential for male fertility: evidence for a role of mitochondrial iron metabolism during spermatogenesis

(2010) Christoph Metzendorf et al.   BMC DEVELOPMENTAL BIOLOGY

Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria

(2009) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Mitochondrial Iron Import through Differential Turnover of Mitoferrin 1 and Mitoferrin 2

(2008) P. N. Paradkar et al.   MOLECULAR AND CELLULAR BIOLOGY