Stabilization of Aliphatic Phosphines by Auxiliary Phosphine Sulfides Offers Zeptomolar Affinity and Unprecedented Selectivity for Probing Biological CuI

Evaluation of Cu(i) binding to the E2 domain of the amyloid precursor protein – a lesson in quantification of metal binding to proteins via ligand competition

(2018) Tessa R. Young et al.   Metallomics

Glutathione limits aquacopper(I) to sub-femtomolar concentrations through cooperative assembly of a tetranuclear cluster

(2017) M. Thomas Morgan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stepwise copper(i) binding to metallothionein: a mixed cooperative and non-cooperative mechanism for all 20 copper ions

(2017) Judith S. Scheller et al.   Metallomics

Unbound position II in MXCXXC metallochaperone model peptides impacts metal binding mode and reactivity: Distinct similarities to whole proteins

(2016) Michal S. Shoshan et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Synthetic fluorescent probes for studying copper in biological systems

(2015) Joseph A. Cotruvo et al.   CHEMICAL SOCIETY REVIEWS

Modulation of copper accumulation and copper-induced toxicity by antioxidants and copper chelators in cultured primary brain astrocytes

(2015) Felix Bulcke et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

What has fluorescent sensing told us about copper and brain malfunction?

(2015) Clara Shen et al.   Metallomics

Novel Cu(I)-Selective Chelators Based on a Bis(phosphorothioyl)amide Scaffold

(2014) Aviran Amir et al.   INORGANIC CHEMISTRY

In vivo and in vitro analyses of amygdalar function reveal a role for copper

(2014) E. D. Gaier et al.   JOURNAL OF NEUROPHYSIOLOGY

Metabolism and functions of copper in brain

(2014) Ivo F. Scheiber et al.   PROGRESS IN NEUROBIOLOGY

Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons

(2014) Patricio A. Castro et al.   Frontiers in Aging Neuroscience

Synthetic fluorescent probes for monovalent copper

(2013) Christoph J Fahrni   CURRENT OPINION IN CHEMICAL BIOLOGY

Golgi in copper homeostasis: a view from the membrane trafficking field

(2013) Roman Polishchuk et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Robust Affinity Standards for Cu(I) Biochemistry

(2013) Pritha Bagchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Sulfur Tripod Glycoconjugate that Releases a High-Affinity Copper Chelator in Hepatocytes

(2012) Anaïs M. Pujol et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cu(I) Affinities of the Domain 1 and 3 Sites in the Human Metallochaperone for Cu,Zn-Superoxide Dismutase

(2012) Stephen Allen et al.   BIOCHEMISTRY

Charting the travels of copper in eukaryotes from yeast to mammals

(2012) Tracy Nevitt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Unification of the Copper(I) Binding Affinities of the Metallo-chaperones Atx1, Atox1, and Related Proteins

(2011) Zhiguang Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Copper Trafficking Mechanism of CXXC-Containing Domains: Insight from the pH-Dependence of Their Cu(I) Affinities

(2011) Adriana Badarau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Relating dynamic protein interactions of metallochaperones with metal transfer at the single-molecule level

(2010) Jaime J. Benítez et al.   FARADAY DISCUSSIONS

Biosynthesis of Phosphonic and Phosphinic Acid Natural Products

(2009) William W. Metcalf et al.   Annual Review of Biochemistry

A Cysteine-Based Tripodal Chelator with a High Affinity and Selectivity for Copper(I)

(2009) Anaïs M. Pujol et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Zinc deficiency impairs neuronal precursor cell proliferation and induces apoptosis via p53-mediated mechanisms

(2008) Rikki S. Corniola et al.   BRAIN RESEARCH

Copper suppresses hippocampus LTP in the rat, but does not alter learning or memory in the morris water maze

(2008) J. Leiva et al.   BRAIN RESEARCH

Probing Transient Copper Chaperone−Wilson Disease Protein Interactions at the Single-Molecule Level with Nanovesicle Trapping

(2008) Jaime J. Benítez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanisms for copper acquisition, distribution and regulation

(2008) Byung-Eun Kim et al.   Nature Chemical Biology