Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer’s-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia
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Title
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer’s-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia
Authors
Keywords
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Journal
Acta Neuropathologica Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-09-09
DOI
10.1186/s40478-022-01439-z
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Note: Only part of the references are listed.- Galectin-3 Promotes Müller Glia Clearance Phagocytosis via MERTK and Reduces Harmful Müller Glia Activation in Inherited and Induced Retinal Degeneration
- (2022) Deborah S. Lew et al. Frontiers in Cellular Neuroscience
- Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma
- (2022) Milica A. Margeta et al. IMMUNITY
- Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease
- (2021) Emma Gerrits et al. ACTA NEUROPATHOLOGICA
- Galectin-3: a key player in microglia-mediated neuroinflammation and Alzheimer's disease
- (2021) Yinyin Tan et al. Cell and Bioscience
- Retinal Vasculopathy in Alzheimer’s Disease
- (2021) Haoshen Shi et al. Frontiers in Neuroscience
- TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration
- (2021) Manling Xie et al. NATURE NEUROSCIENCE
- Identification of early pericyte loss and vascular amyloidosis in Alzheimer’s disease retina
- (2020) Haoshen Shi et al. ACTA NEUROPATHOLOGICA
- Overview of General and Discriminating Markers of Differential Microglia Phenotypes
- (2020) Agnieszka M. Jurga et al. Frontiers in Cellular Neuroscience
- In vivo Retinal Fluorescence Imaging With Curcumin in an Alzheimer Mouse Model
- (2020) Ahmad Sidiqi et al. Frontiers in Neuroscience
- Alzheimer’s Retinopathy: Seeing Disease in the Eyes
- (2020) Nazanin Mirzaei et al. Frontiers in Neuroscience
- Predicting Thioflavin Fluorescence of Retinal Amyloid Deposits Associated With Alzheimer's Disease from Their Polarimetric Properties
- (2020) Yunyi Qiu et al. Translational Vision Science & Technology
- Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer’s disease
- (2020) Haoshen Shi et al. Acta Neuropathologica Communications
- Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk
- (2019) Iris E. Jansen et al. NATURE GENETICS
- Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease
- (2019) Antonio Boza-Serrano et al. ACTA NEUROPATHOLOGICA
- Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer’s disease
- (2019) Chih-Chieh Tao et al. CELL DEATH AND DIFFERENTIATION
- Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer’s Disease Patients, Possible Biomarkers for Early Diagnosis
- (2019) Alfonso Grimaldi et al. Frontiers in Neuroscience
- Microglia in Retinal Degeneration
- (2019) Khalid Rashid et al. Frontiers in Immunology
- Retinal vessel changes in cerebrovascular disease
- (2019) Oana M. Dumitrascu et al. CURRENT OPINION IN NEUROLOGY
- Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington’s disease
- (2019) Jian Jing Siew et al. Nature Communications
- Improvement of insulin signalling rescues inflammatory cardiac dysfunction
- (2019) Isehaq Al-Huseini et al. Scientific Reports
- Levels of Retinal Amyloid-β Correlate with Levels of Retinal IAPP and Hippocampal Amyloid-β in Neuropathologically Evaluated Individuals
- (2019) Nina Schultz et al. JOURNAL OF ALZHEIMERS DISEASE
- A novel role for osteopontin in macrophage-mediated amyloid-β clearance in Alzheimer’s models
- (2018) Altan Rentsendorj et al. BRAIN BEHAVIOR AND IMMUNITY
- Microglia and Astrocytes in Alzheimer's Disease: Implications for Therapy
- (2018) Marc Fakhoury Current Neuropharmacology
- Retinal microglia – A key player in healthy and diseased retina
- (2018) Gurugirijha Rathnasamy et al. PROGRESS IN NEUROBIOLOGY
- Inflammation, neurodegeneration and protein aggregation in the retina as ocular biomarkers for Alzheimer’s disease in the 3xTg-AD mouse model
- (2018) Alfonso Grimaldi et al. Cell Death & Disease
- Inhibition of MicroRNA‐155 Supports Endothelial Tight Junction Integrity Following Oxygen‐Glucose Deprivation
- (2018) Juan Carlos Pena‐Philippides et al. Journal of the American Heart Association
- Microglia and Beyond: Innate Immune Cells As Regulators of Brain Development and Behavioral Function
- (2018) Kathryn M. Lenz et al. Frontiers in Immunology
- 17β-estradiol ameliorates oxidative stress and blue light-emitting diode-induced retinal degeneration by decreasing apoptosis and enhancing autophagy
- (2018) Qingquan Wei et al. Drug Design Development and Therapy
- Microglia in Neurological Diseases: A Road Map to Brain-Disease Dependent-Inflammatory Response
- (2018) Sara Bachiller et al. Frontiers in Cellular Neuroscience
- Amyloid-beta and phosphorylated tau in post-mortem Alzheimer’s disease retinas
- (2018) Jurre den Haan et al. Acta Neuropathologica Communications
- Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microglia
- (2018) Melanie Hüttenrauch et al. Acta Neuropathologica Communications
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk
- (2017) Anastasia G. Efthymiou et al. Molecular Neurodegeneration
- Optical Coherence Tomography in Alzheimer’s Disease and Other Neurodegenerative Diseases
- (2017) Jonah Doustar et al. Frontiers in Neurology
- Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes
- (2017) Mehdi Mirzaei et al. Scientific Reports
- Ocular indicators of Alzheimer’s: exploring disease in the retina
- (2016) Nadav J. Hart et al. ACTA NEUROPATHOLOGICA
- Neuroinflammation in Alzheimer's disease: Current evidence and future directions
- (2016) Valeria Calsolaro et al. Alzheimers & Dementia
- Amyloid β accumulation and inner retinal degenerative changes in Alzheimer’s disease transgenic mouse
- (2016) Vivek K. Gupta et al. NEUROSCIENCE LETTERS
- The Emerging Role of MicroRNA-155 in Cardiovascular Diseases
- (2016) Richard Y. Cao et al. Biomed Research International
- Melanopsin retinal ganglion cell loss in Alzheimer disease
- (2015) Chiara La Morgia et al. ANNALS OF NEUROLOGY
- Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis
- (2015) Celeste M. Karch et al. BIOLOGICAL PSYCHIATRY
- Osteopontin is proteolytically processed by matrix metalloproteinase 9
- (2015) Merry L. Lindsey et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
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- (2015) Ran Antes et al. Current Alzheimer Research
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- (2015) Lixiong Gao et al. EXPERIMENTAL EYE RESEARCH
- Physiological roles of miR-155
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- (2015) Oscar Manouchehrian et al. Journal of Neuroinflammation
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- (2015) Michael T Heneka et al. LANCET NEUROLOGY
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- (2015) Inge R Holtman et al. Acta Neuropathologica Communications
- Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice
- (2014) Oleg Butovsky et al. ANNALS OF NEUROLOGY
- Notch-Dependent Repression of miR-155 in the Bone Marrow Niche Regulates Hematopoiesis in an NF-κB-Dependent Manner
- (2014) Lin Wang et al. Cell Stem Cell
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- (2014) Elizabeth C Martin et al. Molecular Cancer
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- (2014) Anna Carolina Carvalho da Fonseca et al. Frontiers in Cellular Neuroscience
- Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway
- (2013) Gang Wan et al. Autophagy
- Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
- (2013) Christopher N. Parkhurst et al. CELL
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2013) Oleg Butovsky et al. NATURE NEUROSCIENCE
- The microglial sensome revealed by direct RNA sequencing
- (2013) Suzanne E Hickman et al. NATURE NEUROSCIENCE
- Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice
- (2013) Marie Orre et al. NEUROBIOLOGY OF AGING
- Long-Term In Vivo Imaging of Fibrillar Tau in the Retina of P301S Transgenic Mice
- (2013) Christian Schön et al. PLoS One
- Suppressed Retinal Degeneration in Aged Wild Type and APPswe/PS1ΔE9 Mice by Bone Marrow Transplantation
- (2013) Yue Yang et al. PLoS One
- A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
- (2013) Isaac M. Chiu et al. Cell Reports
- Retinal vascular biomarkers for early detection and monitoring of Alzheimer’s disease
- (2013) S Frost et al. Translational Psychiatry
- TNF-α inhibits PPARβ/δ activity and SIRT1 expression through NF-κB in human adipocytes
- (2012) Lucía Serrano-Marco et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The Oncogenic Role of miR-155 in Breast Cancer
- (2012) S. Mattiske et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Eukaryotic Initiation Factor 2 (eIF2) Signaling Regulates Proinflammatory Cytokine Expression and Bacterial Invasion
- (2012) Niraj Shrestha et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Galectin-3 Is Required for Resident Microglia Activation and Proliferation in Response to Ischemic Injury
- (2012) M. Lalancette-Hebert et al. JOURNAL OF NEUROSCIENCE
- Alzheimers Disease in the Retina: Imaging Retinal Aß Plaques for Early Diagnosis and Therapy Assessment
- (2012) Yosef Koronyo et al. Neurodegenerative Diseases
- Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases
- (2011) Joshua A. Smith et al. BRAIN RESEARCH BULLETIN
- Dectin-1 mediatesin vitrophagocytosis ofCandida albicansyeast cells by retinal microglia: Figure 1
- (2011) Victoria Maneu et al. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
- TNF- Signals Through PKC /NF- B to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability
- (2010) C. A. Aveleira et al. DIABETES
- Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model
- (2010) Maya Koronyo-Hamaoui et al. NEUROIMAGE
- Efficient inhibition of miR-155 function in vivo by peptide nucleic acids
- (2010) Martin M. Fabani et al. NUCLEIC ACIDS RESEARCH
- Amyloid-Peptide Vaccinations Reduce β-Amyloid Plaques but Exacerbate Vascular Deposition and Inflammation in the Retina of Alzheimer’s Transgenic Mice
- (2009) Bingqian Liu et al. AMERICAN JOURNAL OF PATHOLOGY
- The role of osteopontin in inflammatory processes
- (2009) Susan Amanda Lund et al. Journal of Cell Communication and Signaling
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