Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer’s disease

Identification of early pericyte loss and vascular amyloidosis in Alzheimer’s disease retina

(2020) Haoshen Shi et al.   ACTA NEUROPATHOLOGICA

Retinal imaging think tank convened by the Alzheimer's Association to examine its promise in the early detection of Alzheimer's

(2020) Peter J. Snyder et al.   Alzheimers & Dementia

Physiological blood–brain transport is impaired with age by a shift in transcytosis

(2020) Andrew C. Yang et al.   NATURE

In vivo Retinal Fluorescence Imaging With Curcumin in an Alzheimer Mouse Model

(2020) Ahmad Sidiqi et al.   Frontiers in Neuroscience

Amyloid Beta Immunoreactivity in the Retinal Ganglion Cell Layer of the Alzheimer’s Eye

(2020) Sieun Lee et al.   Frontiers in Neuroscience

Parallels between retinal and brain pathology and response to immunotherapy in old, late‐stage Alzheimer's disease mouse models

(2020) Jonah Doustar et al.   AGING CELL

Retinal Levels of Amyloid Beta Correlate with Cerebral Levels of Amyloid Beta in Young APPswe/PS1dE9 Transgenic Mice before Onset of Alzheimer’s Disease

(2020) Xi Mei et al.   BEHAVIOURAL NEUROLOGY

Alzheimer’s Retinopathy: Seeing Disease in the Eyes

(2020) Nazanin Mirzaei et al.   Frontiers in Neuroscience

Vascular Dysfunction in Alzheimer’s Disease: A Prelude to the Pathological Process or a Consequence of It?

(2019) Govindpani et al.   Journal of Clinical Medicine

Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer’s Disease Patients, Possible Biomarkers for Early Diagnosis

(2019) Alfonso Grimaldi et al.   Frontiers in Neuroscience

A longitudinal assessment of retinal function and structure in the APP/PS1 transgenic mouse model of Alzheimer’s disease

(2019) Dana Georgevsky et al.   Translational Neurodegeneration

Retinal vessel changes in cerebrovascular disease

(2019) Oana M. Dumitrascu et al.   CURRENT OPINION IN NEUROLOGY

Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer’s disease

(2019) Xavier Hadoux et al.   Nature Communications

Levels of Retinal Amyloid-β Correlate with Levels of Retinal IAPP and Hippocampal Amyloid-β in Neuropathologically Evaluated Individuals

(2019) Nina Schultz et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid-beta 1-40 is associated with alterations in NG2+ pericyte population ex vivo and in vitro

(2018) Nina Schultz et al.   AGING CELL

A novel role for osteopontin in macrophage-mediated amyloid-β clearance in Alzheimer’s models

(2018) Altan Rentsendorj et al.   BRAIN BEHAVIOR AND IMMUNITY

Neurodegeneration in diabetic retinopathy: does it really matter?

(2018) Rafael Simó et al.   DIABETOLOGIA

Characterization of Site-Specific Phosphorylation of NF-κB p65 in Retinal Cells in Response to High Glucose and Cytokine Polarization

(2018) Haoshen Shi et al.   MEDIATORS OF INFLAMMATION

Retinal signs and 20-year cognitive decline in the Atherosclerosis Risk in Communities Study

(2018) Jennifer A. Deal et al.   NEUROLOGY

Peripheral Retinal Imaging Biomarkers for Alzheimer’s Disease: A Pilot Study

(2018) Lajos Csincsik et al.   OPHTHALMIC RESEARCH

Recognition of Personally Familiar Scenes in Patients with Very Mild Alzheimer's Disease: Effects of Spatial Frequency and Luminance

(2018) Yen-Ti Lee et al.   JOURNAL OF ALZHEIMERS DISEASE

Association of Preclinical Alzheimer Disease With Optical Coherence Tomographic Angiography Findings

(2018) Bliss Elizabeth O’Bryhim et al.   JAMA Ophthalmology

Investigating Multimodal Diagnostic Eye Biomarkers of Cognitive Impairment by Measuring Vascular and Neurogenic Changes in the Retina

(2018) Delia Cabrera DeBuc et al.   Frontiers in Physiology

Amyloid-beta and phosphorylated tau in post-mortem Alzheimer’s disease retinas

(2018) Jurre den Haan et al.   Acta Neuropathologica Communications

Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer’s Disease

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Retinal Scan for Alzheimer Disease

(2017) Jennifer Abbasi   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Blood-Retinal Barrier in the Management of Retinal Disease: EURETINA Award Lecture

(2017) José Cunha-Vaz   OPHTHALMOLOGICA

Pericytes, an overlooked player in vascular pathobiology

(2017) David Ferland-McCollough et al.   PHARMACOLOGY & THERAPEUTICS

The inner blood-retinal barrier: Cellular basis and development

(2017) Mónica Díaz-Coránguez et al.   VISION RESEARCH

Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer’s Disease and Related Tauopathies

(2017) Diana L Castillo-Carranza et al.   Aging and Disease

Nuclear Factor-Kappa B and Alzheimer Disease, Unifying Genetic and Environmental Risk Factors from Cell to Humans

(2017) Simon Vann Jones et al.   Frontiers in Immunology

Optical Coherence Tomography in Alzheimer’s Disease and Other Neurodegenerative Diseases

(2017) Jonah Doustar et al.   Frontiers in Neurology

Ocular Biomarkers for Early Detection of Alzheimer's Disease

(2017) Shaun Frost et al.   JOURNAL OF ALZHEIMERS DISEASE

NF-κB as a Key Mediator of Brain Inflammation in Alzheimer’s Disease

(2017) Chul Ju Hwang et al.   CNS & Neurological Disorders-Drug Targets

Ocular indicators of Alzheimer’s: exploring disease in the retina

(2016) Nadav J. Hart et al.   ACTA NEUROPATHOLOGICA

Neurovascular unit impairment in early Alzheimer's disease measured with magnetic resonance imaging

(2016) Harm J. van de Haar et al.   NEUROBIOLOGY OF AGING

Amyloid β accumulation and inner retinal degenerative changes in Alzheimer’s disease transgenic mouse

(2016) Vivek K. Gupta et al.   NEUROSCIENCE LETTERS

Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus

(2016) Elliott H. Sohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease

(2016) Harm J. van de Haar et al.   RADIOLOGY

The Regulation of NF-κB Subunits by Phosphorylation

(2016) Frank Christian et al.   Cells

Retinal amyloid peptides and complement factor H in transgenic models of Alzheimerʼs disease

(2016) Peter N. Alexandrov et al.   NEUROREPORT

Melanopsin retinal ganglion cell loss in Alzheimer disease

(2015) Chiara La Morgia et al.   ANNALS OF NEUROLOGY

Cerebral perfusion in the predementia stages of Alzheimer’s disease

(2015) Maja A. A. Binnewijzend et al.   EUROPEAN RADIOLOGY

Neuroprotective effect of memantine on the retinal ganglion cells of APPswe/PS1ΔE9 mice and its immunomodulatory mechanisms

(2015) Lixiong Gao et al.   EXPERIMENTAL EYE RESEARCH

Behavioral abnormalities in APPSwe/PS1dE9 mouse model of AD-like pathology: comparative analysis across multiple behavioral domains

(2015) Christopher Janus et al.   NEUROBIOLOGY OF AGING

Connecting the Retina to the Brain

(2014) Lynda Erskine et al.   ASN Neuro

Negatively regulating TLR4/NF-κB signaling via PPARα in endotoxin-induced uveitis

(2014) Wei Shen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer’s-like cognitive decline

(2014) Kenneth E. Bernstein et al.   JOURNAL OF CLINICAL INVESTIGATION

Intracellular amyloid beta alters the tight junction of retinal pigment epithelium in 5XFAD mice

(2014) Sung Wook Park et al.   NEUROBIOLOGY OF AGING

Pericyte Loss in Diabetic Retinopathy: Mechanisms and Consequences

(2013) Elena Beltramo et al.   CURRENT MEDICINAL CHEMISTRY

Long-Term In Vivo Imaging of Fibrillar Tau in the Retina of P301S Transgenic Mice

(2013) Christian Schön et al.   PLoS One

Suppressed Retinal Degeneration in Aged Wild Type and APPswe/PS1ΔE9 Mice by Bone Marrow Transplantation

(2013) Yue Yang et al.   PLoS One

Optical imaging of the chorioretinal vasculature in the living human eye

(2013) D. Y. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Endothelial Cell-to-Cell Junctions: Adhesion and Signaling in Physiology and Pathology

(2013) M. G. Lampugnani   Cold Spring Harbor Perspectives in Medicine

Brain Imaging in Alzheimer Disease

(2013) K. A. Johnson et al.   Cold Spring Harbor Perspectives in Medicine

Retinal vascular biomarkers for early detection and monitoring of Alzheimer’s disease

(2013) S Frost et al.   Translational Psychiatry

Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease

(2012) Jesse D. Sengillo et al.   BRAIN PATHOLOGY

Retinal neuropathy precedes vasculopathy in diabetes: a function-based opportunity for early treatment intervention?

(2012) Anthony J Adams et al.   Clinical and Experimental Optometry

Retinal Nerve Fiber Layer Thickness in Patients With Alzheimer Disease

(2012) Serkan Kirbas et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling

(2012) S.-Y. Kook et al.   JOURNAL OF NEUROSCIENCE

The vascular factor in Alzheimer's disease: A study in Golgi technique and electron microscopy

(2012) Stavros J. Baloyannis et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neuroinflammation and Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy

(2012) Anna Carrano et al.   Neurodegenerative Diseases

Alzheimer’s Disease in the Retina: Imaging Retinal Aß Plaques for Early Diagnosis and Therapy Assessment

(2012) Yosef Koronyo et al.   Neurodegenerative Diseases

Mechanisms of Age-Related Macular Degeneration

(2012) Jayakrishna Ambati et al.   NEURON

Morphological and Pathological Evolution of the Brain Microcirculation in Aging and Alzheimer’s Disease

(2012) Jesse M. Hunter et al.   PLoS One

Cerebral amyloid angiopathy in the elderly

(2011) Anand Viswanathan et al.   ANNALS OF NEUROLOGY

Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy

(2011) Anna Carrano et al.   ANTIOXIDANTS & REDOX SIGNALING

Fluorescein Angiography

(2011) Michael F. Marmor   ARCHIVES OF OPHTHALMOLOGY

Amyloid Triggers Extensive Cerebral Angiogenesis Causing Blood Brain Barrier Permeability and Hypervascularity in Alzheimer's Disease

(2011) Kaan E. Biron et al.   PLoS One

Inflammation in diabetic retinopathy

(2011) Johnny Tang et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Cerebral amyloid angiopathy pathology and cognitive domains in older persons

(2010) Zoe Arvanitakis et al.   ANNALS OF NEUROLOGY

TNF-  Signals Through PKC /NF- B to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability

(2010) C. A. Aveleira et al.   DIABETES

Blood-Retinal Barrier

(2010) José Cunha-Vaz et al.   EUROPEAN JOURNAL OF OPHTHALMOLOGY

Neuropathology of Alzheimer's Disease

(2010) Daniel P. Perl   MOUNT SINAI JOURNAL OF MEDICINE

Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

(2010) Maya Koronyo-Hamaoui et al.   NEUROIMAGE

Amyloid-Peptide Vaccinations Reduce β-Amyloid Plaques but Exacerbate Vascular Deposition and Inflammation in the Retina of Alzheimer’s Transgenic Mice

(2009) Bingqian Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer’s disease

(2009) R. Michael Dutescu et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Evidence of angiogenic vessels in Alzheimer’s disease

(2009) Brinda S. Desai et al.   JOURNAL OF NEURAL TRANSMISSION

Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9

(2009) Maya Koronyo-Hamaoui et al.   JOURNAL OF NEUROCHEMISTRY

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

(2009) Mark Kilgore et al.   NEUROPSYCHOPHARMACOLOGY

High glucose concentration leads to differential expression of tight junction proteins in human retinal pigment epithelial cells

(2009) Marta Villarroel et al.   Endocrinologia y Nutricion

A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain

(2008) Jae K. Ryu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Episodic memory deficits are not related to altered glutamatergic synaptic transmission and plasticity in the CA1 hippocampus of the APPswe/PS1ΔE9-deleted transgenic mice model of β-amyloidosis

(2008) Arturas Volianskis et al.   NEUROBIOLOGY OF AGING