Therapeutic strategies in ischemic cardiomyopathy: Focus on mitochondrial quality surveillance

Mdivi-1 alleviates cardiac fibrosis post myocardial infarction at infarcted border zone, possibly via inhibition of Drp1-Activated mitochondrial fission and oxidative stress

(2022) Jie Ding et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Role of mitochondrial quality surveillance in myocardial infarction: From bench to bedside

(2021) Hao Zhou et al.   AGEING RESEARCH REVIEWS

Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress

(2021) Inna Rabinovich-Nikitin et al.   Autophagy

Synergistic cardioptotection by tilianin and syringin in diabetic cardiomyopathy involves interaction of TLR4/NF-κB/NLRP3 and PGC1a/SIRT3 pathways

(2021) Jianping Yao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ketone Ester D‐β‐Hydroxybutyrate‐(R)‐1,3 Butanediol Prevents Decline in Cardiac Function in Type 2 Diabetic Mice

(2021) Phung N. Thai et al.   Journal of the American Heart Association

Alpha-ketoglutarate ameliorates pressure overload-induced chronic cardiac dysfunction in mice

(2021) Dongqi An et al.   Redox Biology

Ischaemic cardiomyopathy. Pathophysiological insights, diagnostic management and the roles of revascularisation and device treatment. Gaps and dilemmas in the era of advanced technology

(2020) Irina Cabac‐Pogorevici et al.   EUROPEAN JOURNAL OF HEART FAILURE

Drp1-mediated mitochondrial fission promotes renal fibroblast activation and fibrogenesis

(2020) Yating Wang et al.   Cell Death & Disease

Mitochondrial biogenesis: An update

(2020) Lucia‐Doina Popov   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Melatonin alleviates sepsis-induced heart injury through activating the Nrf2 pathway and inhibiting the NLRP3 inflammasome

(2020) Ibtissem Rahim et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Biphasic effect of metformin on human cardiac energetics

(2020) Larisa Emelyanova et al.   Translational Research

Mitochondrial quality surveillance as a therapeutic target in myocardial infarction

(2020) Hang Zhu et al.   Acta Physiologica

Phosphoglycerate mutase 5 exacerbates cardiac ischemia-reperfusion injury through disrupting mitochondrial quality control

(2020) Hang Zhu et al.   Redox Biology

A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats

(2019) Julio C. B. Ferreira et al.   Nature Communications

Propofol Ameliorates H9c2 Cells Apoptosis Induced by Oxygen Glucose Deprivation and Reperfusion Injury via Inhibiting High Levels of Mitochondrial Fusion and Fission

(2019) Lidong Zhao et al.   Frontiers in Pharmacology

Balancing mitochondrial dynamics via increasing mitochondrial fusion attenuates infarct size and left ventricular dysfunction in rats with cardiac ischemia/reperfusion injury

(2019) Chayodom Maneechote et al.   CLINICAL SCIENCE

BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation

(2019) Mark A. Lampert et al.   Autophagy

Interplay between Mitophagy and inflammasome in Neurological Disorders

(2019) Radhika Kesharwani et al.   ACS Chemical Neuroscience

Sodium–glucose co‐transporter 2 inhibition with empagliflozin improves cardiac function in non‐diabetic rats with left ventricular dysfunction after myocardial infarction

(2019) Salva R. Yurista et al.   EUROPEAN JOURNAL OF HEART FAILURE

Postinfarction exercise training alleviates cardiac dysfunction and adverse remodeling via mitochondrial biogenesis and SIRT1/PGC‐1α/PI3K/Akt signaling

(2019) Dandan Jia et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pretreatment with vildagliptin boosts ischemic-postconditioning effects on cardioprotection and expression profile of genes regulating autophagy and mitochondrial fission/fusion in diabetic heart with reperfusion injury

(2019) Lale Pirzeh et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Parkin Regulates Programmed Necrosis and Myocardial Ischemia/Reperfusion Injury by Targeting Cyclophilin-D

(2019) Teng Sun et al.   ANTIOXIDANTS & REDOX SIGNALING

Dissociation of mitochondrial HK-II elicits mitophagy and confers cardioprotection against ischemia

(2019) Valerie P. Tan et al.   Cell Death & Disease

Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury

(2019) Danchen Wu et al.   FASEB JOURNAL

Pathogenesis of cardiac ischemia reperfusion injury is associated with CK2α-disturbed mitochondrial homeostasis via suppression of FUNDC1-related mitophagy

(2018) Hao Zhou et al.   CELL DEATH AND DIFFERENTIATION

Pravastatin improves risk factors but not ischaemic tolerance in obese rats

(2018) Massa Oi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Differential temporal inhibition of mitochondrial fission by Mdivi-1 exerts effective cardioprotection in cardiac ischemia/reperfusion injury

(2018) Chayodom Maneechote et al.   CLINICAL SCIENCE

An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

(2018) Toshiro Saito et al.   JOURNAL OF CLINICAL INVESTIGATION

Melatonin attenuates myocardial ischemia reperfusion injury via improving mitochondrial fusion/mitophagy and activating the AMPK-OPA1 signaling pathways

(2018) Ying Zhang et al.   JOURNAL OF PINEAL RESEARCH

Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission–associated myocardial senescence

(2018) Akiyuki Nishimura et al.   Science Signaling

Ellagic acid antagonizes Bnip3-mediated mitochondrial injury and necrotic cell death of cardiac myocytes

(2017) Abhinav Dhingra et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cardioprotection of dapagliflozin and vildagliptin in rats with cardiac ischemia-reperfusion injury

(2017) Pongpan Tanajak et al.   JOURNAL OF ENDOCRINOLOGY

Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission-VDAC1-HK2-mPTP-mitophagy axis

(2017) Hao Zhou et al.   JOURNAL OF PINEAL RESEARCH

SIRT1 Activation by Resveratrol Alleviates Cardiac Dysfunction via Mitochondrial Regulation in Diabetic Cardiomyopathy Mice

(2017) Sai Ma et al.   Oxidative Medicine and Cellular Longevity

Protective role of STVNa in myocardial ischemia reperfusion injury by inhibiting mitochondrial fission

(2017) Xiaoou Sun et al.   Oncotarget

Mff‐Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS‐Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation‐Involved mPTP Opening

(2017) Hao Zhou et al.   Journal of the American Heart Association

Ripk3 induces mitochondrial apoptosis via inhibition of FUNDC1 mitophagy in cardiac IR injury

(2017) Hao Zhou et al.   Redox Biology

High glucose concentration abrogates sevoflurane post-conditioning cardioprotection by advancing mitochondrial fission but dynamin-related protein 1 inhibitor restores these effects

(2016) J. Yu et al.   Acta Physiologica

Inhibition of mitochondrial fission as a molecular target for cardioprotection: critical importance of the timing of treatment

(2016) Yi Dong et al.   BASIC RESEARCH IN CARDIOLOGY

Mitochondrial biogenesis and clearance: a balancing act

(2016) Christina Ploumi et al.   FEBS Journal

Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity

(2016) A.M. Bertholet et al.   NEUROBIOLOGY OF DISEASE

Bicarbonate Increases Ischemia-Reperfusion Damage by Inhibiting Mitophagy

(2016) Bruno B. Queliconi et al.   PLoS One

Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts

(2015) Moshi Song et al.   Cell Metabolism

Bnip3 Binds and Activates p300: Possible Role in Cardiac Transcription and Myocyte Morphology

(2015) John W. Thompson et al.   PLoS One

Protective Effect of Sevoflurane Postconditioning against Cardiac Ischemia/Reperfusion Injury via Ameliorating Mitochondrial Impairment, Oxidative Stress and Rescuing Autophagic Clearance

(2015) Peng Yu et al.   PLoS One

Mitochondrial Genome Linearization Is a Causative Factor for Cardiomyopathy in Mice and Drosophila

(2013) Yun Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitophagy Is Required for Acute Cardioprotection by Simvastatin

(2013) Allen M. Andres et al.   ANTIOXIDANTS & REDOX SIGNALING

Dynasore Protects Mitochondria and Improves Cardiac Lusitropy in Langendorff Perfused Mouse Heart

(2013) Danchen Gao et al.   PLoS One

Hydrogen Peroxide–Mediated SERCA Cysteine 674 Oxidation Contributes to Impaired Cardiac Myocyte Relaxation in Senescent Mouse Heart

(2013) Fuzhong Qin et al.   Journal of the American Heart Association

Acute Inhibition of Excessive Mitochondrial Fission After Myocardial Infarction Prevents Long‐term Cardiac Dysfunction

(2013) Marie‐Hélène Disatnik et al.   Journal of the American Heart Association

Mitochondrial fission proteins Fis1 and Mdv1, but not Dnm1, play a role in maintenance of heteroplasmy in budding yeast

(2012) Elliot Bradshaw et al.   FEBS LETTERS

PGC-1 Proteins and Heart Failure

(2012) Christian Riehle et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death

(2011) Kyriakos N. Papanicolaou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis

(2011) Yun Chen et al.   CIRCULATION RESEARCH

Fine-Tuning of Drp1/Fis1 Availability by AKAP121/Siah2 Regulates Mitochondrial Adaptation to Hypoxia

(2011) Hyungsoo Kim et al.   MOLECULAR CELL

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

(2010) Sang-Bing Ong et al.   CIRCULATION

Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice

(2010) Preeti Ahuja et al.   JOURNAL OF CLINICAL INVESTIGATION

Parkin-induced mitophagy in the pathogenesis of Parkinson disease

(2009) Derek Narendra et al.   Autophagy