Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress

BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy

(2020) Ermin Li et al.   Protein & Cell

Mitophagy Is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy

(2019) Mingming Tong et al.   CIRCULATION RESEARCH

Circadian-Regulated Cell Death in Cardiovascular Diseases

(2019) Inna Rabinovich-Nikitin et al.   CIRCULATION

Impaired NF-κB signalling underlies cyclophilin D-mediated mitochondrial permeability transition pore opening in doxorubicin cardiomyopathy

(2019) Rimpy Dhingra et al.   CARDIOVASCULAR RESEARCH

Diabetes, Hypertension, and Cardiovascular Disease: Clinical Insights and Vascular Mechanisms

(2018) John R. Petrie et al.   CANADIAN JOURNAL OF CARDIOLOGY

Circadian Rhythm Abnormalities in Parkinson’s Disease from Humans to Flies and Back

(2018) Federica De Lazzari et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

(2018) Toshiro Saito et al.   JOURNAL OF CLINICAL INVESTIGATION

Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease

(2017) Faisal J. Alibhai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac Clocks and Preclinical Translation

(2017) Priya Mistry et al.   Heart Failure Clinics

Fuel availability and fate in cardiac metabolism: A tale of two substrates

(2016) Florencia Pascual et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart FailureCLINICAL PERSPECTIVE

(2016) Akihiro Shirakabe et al.   CIRCULATION

Evaluating mitochondrial autophagy in the mouse heart

(2016) Akihiro Shirakabe et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Consequences of Circadian and Sleep Disturbances for the Cardiovascular System

(2015) Faisal J. Alibhai et al.   CANADIAN JOURNAL OF CARDIOLOGY

Hepatic Bmal1 Regulates Rhythmic Mitochondrial Dynamics and Promotes Metabolic Fitness

(2015) David Jacobi et al.   Cell Metabolism

Disruption of Circadian Rhythms and Sleep on Critical Illness and the Impact on Cardiovascular Events

(2015) Cristine Reitz et al.   CURRENT PHARMACEUTICAL DESIGN

Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3) has a key role in the mitochondrial dysfunction induced by mutant huntingtin

(2015) Francesca Sassone et al.   HUMAN MOLECULAR GENETICS

Influence of the Cardiomyocyte Circadian Clock on Cardiac Physiology and Pathophysiology

(2015) Tami A. Martino et al.   JOURNAL OF BIOLOGICAL RHYTHMS

PDK2-mediated alternative splicing switches Bnip3 from cell death to cell survival

(2015) Hongying Gang et al.   JOURNAL OF CELL BIOLOGY

Cancer/Testis Antigen PASD1 Silences the Circadian Clock

(2015) Alicia K. Michael et al.   MOLECULAR CELL

Orchestrating high-throughput genomic analysis with Bioconductor

(2015) Wolfgang Huber et al.   NATURE METHODS

The day/night proteome in the murine heart

(2014) Peter Podobed et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Short-Term Disruption of Diurnal Rhythms After Murine Myocardial Infarction Adversely Affects Long-Term Myocardial Structure and Function

(2014) Faisal J. Alibhai et al.   CIRCULATION RESEARCH

New Insights into the Role of Mitochondrial Dynamics and Autophagy during Oxidative Stress and Aging in the Heart

(2014) Yoshiyuki Ikeda et al.   Oxidative Medicine and Cellular Longevity

Circadian Regulation of Myocardial Sarcomeric Titin-cap (Tcap, Telethonin): Identification of Cardiac Clock-Controlled Genes Using Open Access Bioinformatics Data

(2014) Peter S. Podobed et al.   PLoS One

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

(2013) Marc Liesa et al.   Cell Metabolism

Bidirectional Regulation of Nuclear Factor-κB and Mammalian Target of Rapamycin Signaling Functionally Links Bnip3 Gene Repression and Cell Survival of Ventricular Myocytes

(2013) Rimpy Dhingra et al.   Circulation-Heart Failure

Development of dilated cardiomyopathy in Bmal1-deficient mice

(2012) Mellani Lefta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

(2012) Subir K. Roy Chowdhury et al.   BRAIN

Chronomics of Pressure Overload–Induced Cardiac Hypertrophy in Mice Reveals Altered Day/Night Gene Expression and Biomarkers of Heart Disease

(2012) Elena V. Tsimakouridze et al.   CHRONOBIOLOGY INTERNATIONAL

Mitochondria and Mitophagy

(2012) Dieter A. Kubli et al.   CIRCULATION RESEARCH

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

(2012) N. Huang et al.   SCIENCE

Crosstalk between Components of Circadian and Metabolic Cycles in Mammals

(2011) Gad Asher et al.   Cell Metabolism

A Sensitive and Quantitative Technique for Detecting Autophagic Events Based on Lysosomal Delivery

(2011) Hiroyuki Katayama et al.   CHEMISTRY & BIOLOGY

A Novel Hypoxia-Inducible Spliced Variant of Mitochondrial Death Gene Bnip3 Promotes Survival of Ventricular Myocytes

(2011) Hongying Gang et al.   CIRCULATION RESEARCH

Circadian rhythms and cardiovascular health

(2011) Francesco Portaluppi et al.   SLEEP MEDICINE REVIEWS

Oxidative Stress Stimulates Autophagic Flux During Ischemia/Reperfusion

(2010) Nirmala Hariharan et al.   ANTIOXIDANTS & REDOX SIGNALING

The Cardiomyocyte Circadian Clock

(2010) David J. Durgan et al.   CIRCULATION RESEARCH

Clocks not winding down: unravelling circadian networks

(2010) Eric E. Zhang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Circadian Integration of Metabolism and Energetics

(2010) J. Bass et al.   SCIENCE

Gene ontology analysis for RNA-seq: accounting for selection bias

(2010) Matthew D Young et al.   GENOME BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

(2009) Brian M. Zid et al.   CELL

Oscillating perceptions: the ups and downs of the CLOCK protein in the mouse circadian system

(2009) Jason P. Debruyne   JOURNAL OF GENETICS

Adverse metabolic and cardiovascular consequences of circadian misalignment

(2009) F. A. J. L. Scheer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for an Overlapping Role of CLOCK and NPAS2 Transcription Factors in Liver Circadian Oscillators

(2008) C. Bertolucci et al.   MOLECULAR AND CELLULAR BIOLOGY

Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression

(2007) Molly S. Bray et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY