Bacteria loaded with glucose polymer and photosensitive ICG silicon-nanoparticles for glioblastoma photothermal immunotherapy

Strategies for delivering therapeutics across the blood–brain barrier

(2021) Georg C. Terstappen et al.   NATURE REVIEWS DRUG DISCOVERY

Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia

(2021) Carmen Gasca-Salas et al.   Nature Communications

Bacteria‐Based Cancer Immunotherapy

(2021) Xuehui Huang et al.   Advanced Science

Antibody Engineered Platelets Attracted by Bacteria‐Induced Tumor‐Specific Blood Coagulation for Checkpoint Inhibitor Immunotherapy

(2021) Jin‐Xuan Fan et al.   ADVANCED FUNCTIONAL MATERIALS

Cascade‐Amplifying Synergistic Therapy for Intracranial Glioma via Endogenous Reactive Oxygen Species‐Triggered “All‐in‐One” Nanoplatform

(2021) Pengying Wu et al.   ADVANCED FUNCTIONAL MATERIALS

Role of Polymeric Local Drug Delivery in Multimodal Treatment of Malignant Glioma: A Review

(2021) Yuan-Yun Tseng et al.   International Journal of Nanomedicine

Spatiotemporally Controllable Distribution of Combination Therapeutics in Solid Tumors by Dually Modified Bacteria

(2021) Lu Wang et al.   ADVANCED MATERIALS

Engineering bioluminescent bacteria to boost photodynamic therapy and systemic anti-tumor immunity for synergistic cancer treatment

(2021) Zhijuan Yang et al.   BIOMATERIALS

Camouflaging Nanoparticles with Brain Metastatic Tumor Cell Membranes: A New Strategy to Traverse Blood–Brain Barrier for Imaging and Therapy of Brain Tumors

(2020) Caixia Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Hybrid magnetic nanovectors promote selective glioblastoma cell death through a combined effect of lysosomal membrane permeabilization and chemotherapy

(2020) Carlotta Pucci et al.   ACS Applied Materials & Interfaces

Albumin-Based Nanotheranostic Probe with Hypoxia Alleviating Potentiates Synchronous Multimodal Imaging and Phototherapy for Glioma

(2020) Zhenzhen Yang et al.   ACS Nano

Multifunctional Nanoparticle Loaded Injectable Thermoresponsive Hydrogel as NIR Controlled Release Platform for Local Photothermal Immunotherapy to Prevent Breast Cancer Postoperative Recurrence and Metastases

(2020) Yan Peng Jia et al.   ADVANCED FUNCTIONAL MATERIALS

Designing immunogenic nanotherapeutics for photothermal-triggered immunotherapy involving reprogramming immunosuppression and activating systemic antitumor responses

(2020) Jing Wang et al.   BIOMATERIALS

GSH depletion liposome adjuvant for augmenting the photothermal immunotherapy of breast cancer

(2020) Zhanwei Zhou et al.   Science Advances

Bacteria-triggered tumor-specific thrombosis to enable potent photothermal immunotherapy of cancer

(2020) Xuan Yi et al.   Science Advances

“Trojan Horse” Salmonella Enabling Tumor Homing of Silver Nanoparticles via Neutrophil Infiltration for Synergistic Tumor Therapy and Enhanced Biosafety

(2020) Ze Mi et al.   NANO LETTERS

Challenges to curing primary brain tumours

(2019) Kenneth Aldape et al.   Nature Reviews Clinical Oncology

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

(2019) Timothy F. Cloughesy et al.   NATURE MEDICINE

Efficacy of systemic temozolomide‐activated phage‐targeted gene therapy in human glioblastoma

(2019) Justyna Magdalena Przystal et al.   EMBO Molecular Medicine

Nanophotosensitizer-engineered Salmonella bacteria with hypoxia targeting and photothermal-assisted mutual bioaccumulation for solid tumor therapy

(2019) Fuming Chen et al.   BIOMATERIALS

Antisense Oligonucleotide Therapies for Neurodegenerative Diseases

(2019) C. Frank Bennett et al.   Annual Review of Neuroscience

Combination of Bacterial‐Photothermal Therapy with an Anti‐PD‐1 Peptide Depot for Enhanced Immunity against Advanced Cancer

(2019) Wenfei Chen et al.   ADVANCED FUNCTIONAL MATERIALS

Nose-to-brain delivery of antiglioblastoma drugs embedded into lipid nanocarrier systems: status quo and outlook

(2019) Fakhara Sabir et al.   DRUG DISCOVERY TODAY

Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide

(2019) Lin-Ping Wu et al.   Nature Communications

Multifunctional nanoagents for ultrasensitive imaging and photoactive killing of Gram-negative and Gram-positive bacteria

(2019) Jiali Tang et al.   Nature Communications

Bacteria-cancer interactions: bacteria-based cancer therapy

(2019) Mai Thi-Quynh Duong et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Bacteria-Driven Hypoxia Targeting for Combined Biotherapy and Photothermal Therapy

(2018) Wenfei Chen et al.   ACS Nano

Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs

(2018) Mukta Agrawal et al.   JOURNAL OF CONTROLLED RELEASE

Novel PET and Near Infrared Imaging Probes for the Specific Detection of Bacterial Infections Associated With Cardiac Devices

(2018) Kiyoko Takemiya et al.   JACC-Cardiovascular Imaging

Specific Imaging of Bacterial Infection Using 6″-18F-Fluoromaltotriose: A Second-Generation PET Tracer Targeting the Maltodextrin Transporter in Bacteria

(2017) Gayatri Gowrishankar et al.   JOURNAL OF NUCLEAR MEDICINE

Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence

(2017) Jingwei Xue et al.   Nature Nanotechnology

A journey into the brain: insight into how bacterial pathogens cross blood–brain barriers

(2017) Mathieu Coureuil et al.   NATURE REVIEWS MICROBIOLOGY

Two-step enhanced cancer immunotherapy with engineeredSalmonella typhimuriumsecreting heterologous flagellin

(2017) Jin Hai Zheng et al.   Science Translational Medicine

Chlorin-Based Nanoscale Metal–Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy

(2016) Kuangda Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins

(2016) Sylwia D. Tyrkalska et al.   Nature Communications

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Glioma

(2015) Michael Weller et al.   Nature Reviews Disease Primers

Synthesis of [18F]-labelled Maltose Derivatives as PET Tracers for Imaging Bacterial Infection

(2014) Mohammad Namavari et al.   MOLECULAR IMAGING AND BIOLOGY

Investigation of 6-[18F]-Fluoromaltose as a Novel PET Tracer for Imaging Bacterial Infection

(2014) Gayatri Gowrishankar et al.   PLoS One

Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

(2014) E. Phillips et al.   Science Translational Medicine

Cyclic RGD-Linked Polymeric Micelles for Targeted Delivery of Platinum Anticancer Drugs to Glioblastoma through the Blood–Brain Tumor Barrier

(2013) Yutaka Miura et al.   ACS Nano

Brain Bioavailability of Human Intravenous Immunoglobulin and its Transport through the Murine Blood–Brain Barrier

(2013) Isabelle St-Amour et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Aptamer-functionalized PEG–PLGA nanoparticles for enhanced anti-glioma drug delivery

(2011) Jianwei Guo et al.   BIOMATERIALS

Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma

(2011) Miriam Benezra et al.   JOURNAL OF CLINICAL INVESTIGATION

Maltodextrin-based imaging probes detect bacteria in vivo with high sensitivity and specificity

(2011) Xinghai Ning et al.   NATURE MATERIALS

Permeability of Endothelial and Astrocyte Cocultures: In Vitro Blood–Brain Barrier Models for Drug Delivery Studies

(2010) Guanglei Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Biodegradable luminescent porous silicon nanoparticles for in vivo applications

(2009) Ji-Ho Park et al.   NATURE MATERIALS

Advances in the genetics of glioblastoma: are we reaching critical mass?

(2009) Benjamin Purow et al.   Nature Reviews Neurology

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Mechanisms of microbial traversal of the blood–brain barrier

(2008) Kwang Sik Kim   NATURE REVIEWS MICROBIOLOGY