RNF185 regulates proteostasis in Ebolavirus infection by crosstalk between the calnexin cycle, ERAD, and reticulophagy

Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway

(2022) Bin Wang et al.   Autophagy

The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway

(2021) Tom Cremer et al.   Cell Reports

ER-phagy responses in yeast, plants, and mammalian cells and their crosstalk with UPR and ERAD

(2021) Maurizio Molinari   DEVELOPMENTAL CELL

K27‐linked noncanonic ubiquitination in immune regulation

(2021) Qingqing Zhou et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mechanisms of Selective Autophagy

(2021) Trond Lamark et al.   Annual Review of Cell and Developmental Biology

TRIM25 inhibits infectious bursal disease virus replication by targeting VP3 for ubiquitination and degradation

(2021) Suyan Wang et al.   PLoS Pathogens

The Ebola virus soluble glycoprotein contributes to viral pathogenesis by activating the MAP kinase signaling pathway

(2021) Wakako Furuyama et al.   PLoS Pathogens

ER-Phagy: Quality Control and Turnover of Endoplasmic Reticulum

(2020) Haruka Chino et al.   TRENDS IN CELL BIOLOGY

Calnexin cycle – structural features of the ER chaperone system

(2020) Guennadi Kozlov et al.   FEBS Journal

Ebola

(2020) Heinz Feldmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex

(2020) Michael L. van de Weijer et al.   MOLECULAR CELL

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

(2020) Emma J Fenech et al.   eLife

MARCH8 Inhibits Ebola Virus Glycoprotein, Human Immunodeficiency Virus Type 1 Envelope Glycoprotein, and Avian Influenza Virus H5N1 Hemagglutinin Maturation

(2020) Changqing Yu et al.   mBio

The N-Degron Pathway Mediates ER-phagy

(2019) Chang Hoon Ji et al.   MOLECULAR CELL

Therapeutic strategies to target the Ebola virus life cycle

(2019) Thomas Hoenen et al.   NATURE REVIEWS MICROBIOLOGY

RNF185 modulates JWA ubiquitination and promotes gastric cancer metastasis

(2018) Danping Qiu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Quality Control in the Endoplasmic Reticulum: Crosstalk between ERAD and UPR pathways

(2018) Jiwon Hwang et al.   TRENDS IN BIOCHEMICAL SCIENCES

ER‐to‐lysosome‐associated degradation of proteasome‐resistant ATZ polymers occurs via receptor‐mediated vesicular transport

(2018) Ilaria Fregno et al.   EMBO JOURNAL

Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57

(2018) Sara Piacentini et al.   Scientific Reports

A selective ER‐phagy exerts procollagen quality control via a Calnexin‐FAM134B complex

(2018) Alison Forrester et al.   EMBO JOURNAL

Mechanistic understanding ofN-glycosylation in Ebola virus glycoprotein maturation and function

(2017) Bin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting and translocation of proteins to the endoplasmic reticulum at a glance

(2017) Naama Aviram et al.   JOURNAL OF CELL SCIENCE

Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells

(2017) Shouheng Jin et al.   MOLECULAR CELL

The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response

(2017) Qiang Wang et al.   PLoS Pathogens

An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport

(2016) Marlieke L.M. Jongsma et al.   CELL

Posttranscriptional Regulation of Glycoprotein Quality Control in the Endoplasmic Reticulum Is Controlled by the E2 Ub-Conjugating Enzyme UBC6e

(2016) Masatoshi Hagiwara et al.   MOLECULAR CELL

Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol

(2015) Moritz Hacke et al.   Nature Communications

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes

(2014) Thomas Hoenen et al.   Jove-Journal of Visualized Experiments

RNF185 Is a Novel E3 Ligase of Endoplasmic Reticulum-associated Degradation (ERAD) That Targets Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

(2013) Elma El Khouri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Antigenic Subversion: A Novel Mechanism of Host Immune Evasion by Ebola Virus

(2012) Gopi S. Mohan et al.   PLoS Pathogens

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Steric Shielding of Surface Epitopes and Impaired Immune Recognition Induced by the Ebola Virus Glycoprotein

(2010) Joseph R. Francica et al.   PLoS Pathogens

Genome-Wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle's Dynamics and Signaling

(2008) Wei Li et al.   PLoS One

Requirements for cell rounding and surface protein down-regulation by Ebola virus glycoprotein

(2008) Joseph R. Francica et al.   VIROLOGY