Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling
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Title
Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling
Authors
Keywords
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Journal
eLife
Volume 9, Issue -, Pages -
Publisher
eLife Sciences Publications, Ltd
Online
2020-07-02
DOI
10.7554/elife.57306
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Note: Only part of the references are listed.- Homeostatic regulation of STING protein at the resting state by stabilizer TOLLIP
- (2020) Vladislav Pokatayev et al. NATURE IMMUNOLOGY
- Molecular mechanisms and cellular functions of cGAS–STING signalling
- (2020) Karl-Peter Hopfner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP
- (2019) Guijun Shang et al. NATURE
- Inadequate BiP availability defines endoplasmic reticulum stress
- (2019) Milena Vitale et al. eLife
- ERAD‐dependent control of the Wnt secretory factor Evi
- (2018) Kathrin Glaeser et al. EMBO JOURNAL
- Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1
- (2018) Thaneas Prabakaran et al. EMBO JOURNAL
- Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase
- (2018) Lu-Yi Jiang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides
- (2018) Timothy J. Bergmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation
- (2018) Julia Hülsmann et al. MOLECULAR & CELLULAR PROTEOMICS
- A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates
- (2018) Edmond Y. Huang et al. MOLECULAR BIOLOGY OF THE CELL
- Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xL
- (2018) Yanfang Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Here, there, and everywhere: The importance of ER membrane contact sites
- (2018) Haoxi Wu et al. SCIENCE
- Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation
- (2018) Dara E. Leto et al. MOLECULAR CELL
- The PRIDE database and related tools and resources in 2019: improving support for quantification data
- (2018) Yasset Perez-Riverol et al. NUCLEIC ACIDS RESEARCH
- The BioGRID interaction database: 2019 update
- (2018) Rose Oughtred et al. NUCLEIC ACIDS RESEARCH
- The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1
- (2018) Sam A Menzies et al. eLife
- Characterization of protein complexes of the endoplasmic reticulum-associated degradation E3 ubiquitin ligase Hrd1
- (2017) Jiwon Hwang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD)
- (2017) Jasmin Schulz et al. JOURNAL OF CELL SCIENCE
- Architecture of the human interactome defines protein communities and disease networks
- (2017) Edward L. Huttlin et al. NATURE
- Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
- (2017) Stefan Schoebel et al. NATURE
- Applying systems-level spectral imaging and analysis to reveal the organelle interactome
- (2017) Alex M. Valm et al. NATURE
- ER-associated degradation regulates Alzheimer’s amyloid pathology and memory function by modulating γ-secretase activity
- (2017) Bing Zhu et al. Nature Communications
- TMCO1 Is an ER Ca 2+ Load-Activated Ca 2+ Channel
- (2016) Qiao-Chu Wang et al. CELL
- An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport
- (2016) Marlieke L.M. Jongsma et al. CELL
- A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response
- (2016) Britt Adamson et al. CELL
- Kinetic Analysis of Protein Stability Reveals Age-Dependent Degradation
- (2016) Erik McShane et al. CELL
- Identification of endonuclease domain-containing 1 gene in Japanese flounder Paralichthys olivaceus
- (2016) Zhe-Zhe Lyu et al. FISH & SHELLFISH IMMUNOLOGY
- Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis
- (2016) Anika V. Prabhu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lunapark Is a Component of a Ubiquitin Ligase Complex Localized to the Endoplasmic Reticulum Three-way Junctions
- (2016) Yupeng Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TMEM43/LUMA is a key signaling component mediating EGFR-induced NF-κB activation and tumor progression
- (2016) C Jiang et al. ONCOGENE
- Genome-wide identification and gene expression profiling of ubiquitin ligases for endoplasmic reticulum protein degradation
- (2016) Masayuki Kaneko et al. Scientific Reports
- CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling
- (2016) Matous Hrdinka et al. Cell Reports
- STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease
- (2015) Nicole Dobbs et al. Cell Host & Microbe
- The endoplasmic reticulum: structure, function and response to cellular signaling
- (2015) Dianne S. Schwarz et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Control of p97 function by cofactor binding
- (2015) Alexander Buchberger et al. FEBS LETTERS
- gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum
- (2015) Ting Zhang et al. MOLECULAR BIOLOGY OF THE CELL
- K29-Selective Ubiquitin Binding Domain Reveals Structural Basis of Specificity and Heterotypic Nature of K29 Polyubiquitin
- (2015) Yosua Adi Kristariyanto et al. MOLECULAR CELL
- Identifying the ERAD ubiquitin E3 ligases for viral and cellular targeting of MHC class I
- (2015) D.J.H. van den Boomen et al. MOLECULAR IMMUNOLOGY
- Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest)
- (2015) Manuela K Hospenthal et al. Nature Protocols
- The TOPCONS web server for consensus prediction of membrane protein topology and signal peptides
- (2015) Konstantinos D. Tsirigos et al. NUCLEIC ACIDS RESEARCH
- The Pfam protein families database: towards a more sustainable future
- (2015) Robert D. Finn et al. NUCLEIC ACIDS RESEARCH
- Viruses transfer the antiviral second messenger cGAMP between cells
- (2015) A. Bridgeman et al. SCIENCE
- The critical role of membralin in postnatal motor neuron survival and disease
- (2015) Bo Yang et al. eLife
- Lys11- and Lys48-linked ubiquitin chains interact with p97 during endoplasmic-reticulum-associated degradation
- (2014) Matthew Locke et al. BIOCHEMICAL JOURNAL
- Key Steps in ERAD of Luminal ER Proteins Reconstituted with Purified Components
- (2014) Alexander Stein et al. CELL
- A close-up view of membrane contact sites between the endoplasmic reticulum and the endolysosomal system: From yeast to man
- (2014) Carina Hönscher et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- The E3 Ubiquitin Ligase AMFR and INSIG1 Bridge the Activation of TBK1 Kinase by Modifying the Adaptor STING
- (2014) Qiang Wang et al. IMMUNITY
- ER-associated degradation: Protein quality control and beyond
- (2014) Annamaria Ruggiano et al. JOURNAL OF CELL BIOLOGY
- Small regulators, major consequences - Ca2+ and cholesterol at the endosome-ER interface
- (2014) R. van der Kant et al. JOURNAL OF CELL SCIENCE
- Accurate Protein Complex Retrieval by Affinity Enrichment Mass Spectrometry (AE-MS) Rather than Affinity Purification Mass Spectrometry (AP-MS)
- (2014) Eva C. Keilhauer et al. MOLECULAR & CELLULAR PROTEOMICS
- The E3 Ubiquitin Ligase MARCH6 Degrades Squalene Monooxygenase and Affects 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase and the Cholesterol Synthesis Pathway
- (2014) N. Zelcer et al. MOLECULAR AND CELLULAR BIOLOGY
- Tts1, the fission yeast homologue of the TMEM33 family, functions in NE remodeling during mitosis
- (2014) Dan Zhang et al. MOLECULAR BIOLOGY OF THE CELL
- The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling
- (2014) Xin Cai et al. MOLECULAR CELL
- Cleaning up in the endoplasmic reticulum: ubiquitin in charge
- (2014) John C Christianson et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Quality control of inner nuclear membrane proteins by the Asi complex
- (2014) O. Foresti et al. SCIENCE
- Bax Inhibitor-1 Is Likely a pH-Sensitive Calcium Leak Channel, Not a H+/Ca2+ Exchanger
- (2014) G. Bultynck et al. Science Signaling
- A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation
- (2014) Michael L. van de Weijer et al. Nature Communications
- Genome-wide RNAi Screen Reveals a Role for Multipass Membrane Proteins in Endosome-to-Golgi Retrieval
- (2014) Sophia Y. Breusegem et al. Cell Reports
- RNF26 Temporally Regulates Virus-Triggered Type I Interferon Induction by Two Distinct Mechanisms
- (2014) Yue Qin et al. PLoS Pathogens
- Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol
- (2013) Eva-Maria Küch et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- RNF185 Is a Novel E3 Ligase of Endoplasmic Reticulum-associated Degradation (ERAD) That Targets Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)
- (2013) Elma El Khouri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Peroxisomes take shape
- (2013) Jennifer J. Smith et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments
- (2013) Matthew D. Shoulders et al. Cell Reports
- Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4
- (2013) Ombretta Foresti et al. eLife
- The Ubiquitin Code
- (2012) David Komander et al. Annual Review of Biochemistry
- TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis
- (2012) D Rojas-Rivera et al. CELL DEATH AND DIFFERENTIATION
- Unassembled CD147 is an endogenous endoplasmic reticulum–associated degradation substrate
- (2012) Ryan E. Tyler et al. MOLECULAR BIOLOGY OF THE CELL
- Ubiquitin-Dependent Intramembrane Rhomboid Protease Promotes ERAD of Membrane Proteins
- (2012) Lina Fleig et al. MOLECULAR CELL
- Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis
- (2012) Anna Plechanovová et al. NATURE
- Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system
- (2012) Hemmo Meyer et al. NATURE CELL BIOLOGY
- Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase
- (2011) Youngah Jo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Systematic Search for Endoplasmic Reticulum (ER) Membrane-associated RING Finger Proteins Identifies Nixin/ZNRF4 as a Regulator of Calnexin Stability and ER Homeostasis
- (2011) Albert Neutzner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RNF170 Protein, an Endoplasmic Reticulum Membrane Ubiquitin Ligase, Mediates Inositol 1,4,5-Trisphosphate Receptor Ubiquitination and Degradation
- (2011) Justine P. Lu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Yeast SREBP Cleavage Activation Requires the Golgi Dsc E3 Ligase Complex
- (2011) Emerson V. Stewart et al. MOLECULAR CELL
- Defining human ERAD networks through an integrative mapping strategy
- (2011) John C. Christianson et al. NATURE CELL BIOLOGY
- Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum
- (2011) Ethan J Greenblatt et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mechanism of ubiquitylation by dimeric RING ligase RNF4
- (2011) Anna Plechanovová et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8
- (2011) Y. Jo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comparative evaluation of label-free SINQ normalized spectral index quantitation in the central proteomics facilities pipeline
- (2011) David C. Trudgian et al. PROTEOMICS
- Endosomal transport via ubiquitination
- (2011) Robert C. Piper et al. TRENDS IN CELL BIOLOGY
- Protein quality control in the ER: balancing the ubiquitin checkbook
- (2011) Jasper H.L. Claessen et al. TRENDS IN CELL BIOLOGY
- TMEM43 mutations in emery-dreifuss muscular dystrophy-related myopathy
- (2010) Wen-Chen Liang et al. ANNALS OF NEUROLOGY
- RING domain dimerization is essential for RNF4 function
- (2010) Chu Wai Liew et al. BIOCHEMICAL JOURNAL
- Dynamics of Cullin-RING Ubiquitin Ligase Network Revealed by Systematic Quantitative Proteomics
- (2010) Eric J. Bennett et al. CELL
- Retrotranslocation of a Misfolded Luminal ER Protein by the Ubiquitin-Ligase Hrd1p
- (2010) Pedro Carvalho et al. CELL
- The Cortical ER Network Limits the Permissive Zone for Actomyosin Ring Assembly
- (2010) Dan Zhang et al. CURRENT BIOLOGY
- Herp Regulates Hrd1-mediated Ubiquitylation in a Ubiquitin-like Domain-dependent Manner
- (2010) Melanie Kny et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Defining the Human Deubiquitinating Enzyme Interaction Landscape
- (2009) Mathew E. Sowa et al. CELL
- Quantitative Proteomics Reveals the Function of Unconventional Ubiquitin Chains in Proteasomal Degradation
- (2009) Ping Xu et al. CELL
- Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities
- (2009) Roland Hjerpe et al. EMBO REPORTS
- Evolutionary divergence of valosin-containing protein/cell division cycle protein 48 binding interactions among endoplasmic reticulum-associated degradation proteins
- (2009) Giacomo Morreale et al. FEBS Journal
- Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
- (2009) G. Markson et al. GENOME RESEARCH
- The Ubiquitin Ligase RNF5 Regulates Antiviral Responses by Mediating Degradation of the Adaptor Protein MITA
- (2009) Bo Zhong et al. IMMUNITY
- An Endoplasmic Reticulum (ER) Membrane Complex Composed of SPFH1 and SPFH2 Mediates the ER-associated Degradation of Inositol 1,4,5-Trisphosphate Receptors
- (2009) Margaret M. P. Pearce et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78
- (2009) Ranabir Das et al. MOLECULAR CELL
- A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system
- (2009) Sjoerd J L van Wijk et al. Molecular Systems Biology
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
- Large-scale profiling of protein palmitoylation in mammalian cells
- (2009) Brent R Martin et al. NATURE METHODS
- An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen
- (2009) Benoît Kornmann et al. SCIENCE
- Arrhythmogenic Right Ventricular Cardiomyopathy Type 5 Is a Fully Penetrant, Lethal Arrhythmic Disorder Caused by a Missense Mutation in the TMEM43 Gene
- (2008) Nancy D. Merner et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Ubiquitin ligase Kf-1 is involved in the endoplasmic reticulum-associated degradation pathway
- (2008) Yoshiaki Maruyama et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans
- (2008) K Linke et al. CELL DEATH AND DIFFERENTIATION
- Human XTP3-B Forms an Endoplasmic Reticulum Quality Control Scaffold with the HRD1-SEL1L Ubiquitin Ligase Complex and BiP
- (2008) Nobuko Hosokawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LUMA interacts with emerin and influences its distribution at the inner nuclear membrane
- (2008) Luiza Bengtsson et al. JOURNAL OF CELL SCIENCE
- Gp78 Cooperates with RMA1 in Endoplasmic Reticulum-associated Degradation of CFTRΔF508
- (2008) Daisuke Morito et al. MOLECULAR BIOLOGY OF THE CELL
- Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation
- (2008) Rujun Kang et al. NATURE
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
- OS-9 and GRP94 deliver mutant α1-antitrypsin to the Hrd1–SEL1L ubiquitin ligase complex for ERAD
- (2008) John C. Christianson et al. NATURE CELL BIOLOGY
- IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis
- (2008) Mads Gyrd-Hansen et al. NATURE CELL BIOLOGY
- One step at a time: endoplasmic reticulum-associated degradation
- (2008) Shruthi S. Vembar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Genome-Wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle's Dynamics and Signaling
- (2008) Wei Li et al. PLoS One
- SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins
- (2008) B. Mueller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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