Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis

Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2

(2021) Xiang Luo et al.   CELL DEATH AND DIFFERENTIATION

Combating COVID-19 With Mesenchymal Stem/Stromal Cell Therapy: Promise and Challenges

(2021) Shihua H. Wang et al.   Frontiers in Cell and Developmental Biology

TIM‐4 is critical for KC homeostatic function in the activation and resolution of liver ischemia reperfusion injury

(2021) Ming Ni et al.   HEPATOLOGY

Exosomes from human umbilical cord mesenchymal stem cells attenuate the inflammation of severe steroid-resistant asthma by reshaping macrophage polarization

(2021) Bing Dong et al.   Stem Cell Research & Therapy

Therapeutic implications of transplanted-cell death

(2021) Zachary W. Wagoner et al.   Nature Biomedical Engineering

AKR1B10 inhibits the proliferation and migration of gastric cancer via regulating epithelial-mesenchymal transition

(2021) Xinyu Shao et al.   Aging-US

Stem cell factor SOX2 confers ferroptosis resistance in lung cancer via upregulation of SLC7A11

(2021) Xinbo Wang et al.   CANCER RESEARCH

IL-1β primed mesenchymal stromal cells moderate hemorrhagic shock-induced organ injuries

(2021) Clotilde Aussel et al.   Stem Cell Research & Therapy

Efferocytosis induces macrophage proliferation to help resolve tissue injury

(2021) Brennan D. Gerlach et al.   Cell Metabolism

SPION-MSCs enhance therapeutic efficacy in sepsis by regulating MSC-expressed TRAF1-dependent macrophage polarization

(2021) Yujun Xu et al.   Stem Cell Research & Therapy

IL-1β-primed mesenchymal stromal cells exert enhanced therapeutic effects to alleviate Chronic Prostatitis/Chronic Pelvic Pain Syndrome through systemic immunity

(2021) Hanchao Liu et al.   Stem Cell Research & Therapy

β-glucan-coupled superparamagnetic iron oxide nanoparticles induce trained immunity to protect mice against sepsis

(2021) Yuchen Pan et al.   Theranostics

DNA-coated gold nanoparticles for tracking hepatocyte growth factor secreted by transplanted mesenchymal stem cells in pulmonary fibrosis therapy

(2021) Hongying Bao et al.   Biomaterials Science

Artificially Engineered Cubic Iron Oxide Nanoparticle as a High-Performance Magnetic Particle Imaging Tracer for Stem Cell Tracking

(2020) Qiyue Wang et al.   ACS Nano

In vivo monitoring of dynamic interaction between neutrophil and human umbilical cord blood-derived mesenchymal stem cell in mouse liver during sepsis

(2020) Sung Yong Ahn et al.   Stem Cell Research & Therapy

CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury

(2020) Jayeeta Giri et al.   Cell Reports

Editorial: Safety, Efficacy and Mechanisms of Action of Mesenchymal Stem Cell Therapies

(2020) Guido Moll et al.   Frontiers in Immunology

Hepatic Transferrin Plays a Role in Systemic Iron Homeostasis and Liver Ferroptosis

(2020) Yingying Yu et al.   BLOOD

The clearance of dead cells by efferocytosis

(2020) Emilio Boada-Romero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Near Infrared Fluorescent Nanoplatform for Targeted Intraoperative Resection and Chemotherapeutic Treatment of Glioblastoma

(2020) Derek Reichel et al.   ACS Nano

Human umbilical cord blood–derived MSCs exosome attenuate myocardial injury by inhibiting ferroptosis in acute myocardial infarction mice

(2020) Yufang Song et al.   CELL BIOLOGY AND TOXICOLOGY

Incidence and mortality of hospital- and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis

(2020) C. Fleischmann-Struzek et al.   INTENSIVE CARE MEDICINE

Ferumoxytol MR Angiography versus Duplex US for Vascular Mapping before Arteriovenous Fistula Surgery for Hemodialysis

(2020) Sokratis Stoumpos et al.   RADIOLOGY

Mesenchymal stem cells offer a drug-tolerant and immune-privileged niche to Mycobacterium tuberculosis

(2020) Neharika Jain et al.   Nature Communications

Author Correction: Ultra Short Echo Time MRI of Iron-Labelled Mesenchymal Stem Cells in an Ovine Osteochondral Defect Model

(2020) Joshua D. Kaggie et al.   Scientific Reports

Ferroptosis: machinery and regulation

(2020) Xin Chen et al.   Autophagy

Mesenchymal Stem/Stromal Cells Increase Cardiac MIR-187-3P Expression in Polymicrobial Animal Model of Sepsis

(2020) Amin M. Ektesabi et al.   SHOCK

The lipogenic regulator SREBF2 induces Transferrin in circulating melanoma cells and suppresses ferroptosis

(2020) Xin Hong et al.   Cancer Discovery

Intranasal delivery of MSC-derived exosomes attenuates allergic asthma via expanding IL-10 producing lung interstitial macrophages in mice

(2020) Jiling Ren et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mesenchymal stromal cell-derived exosomes attenuate myocardial ischaemia-reperfusion injury through miR-182-regulated macrophage polarization

(2019) Jinxuan Zhao et al.   CARDIOVASCULAR RESEARCH

The release and activity of HMGB1 in ferroptosis

(2019) Qirong Wen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Pros and Cons of Mesenchymal Stem Cell-Based Therapies

(2019) Aleksandra Musiał-Wysocka et al.   CELL TRANSPLANTATION

Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxia

(2019) Zan Li et al.   Redox Biology

JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice

(2018) Xinxin Song et al.   GASTROENTEROLOGY

Sepsis and septic shock

(2018) Maurizio Cecconi et al.   LANCET

Mesenchymal-myeloid interaction in the regulation of immunity

(2018) Tik Shing Cheung et al.   SEMINARS IN IMMUNOLOGY

Immunomodulation By Therapeutic Mesenchymal Stromal Cells (MSC) Is Triggered Through Phagocytosis of MSC By Monocytic Cells

(2018) Samantha F.H. de Witte et al.   STEM CELLS

Antimicrobial effects of mesenchymal stem cells primed by modified LPS on bacterial clearance in sepsis

(2018) Pardis Saeedi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation

(2017) Antonio Galleu et al.   Science Translational Medicine

Exosomal miR-146a Contributes to the Enhanced Therapeutic Efficacy of Interleukin-1β-Primed Mesenchymal Stem Cells Against Sepsis

(2017) Yuxian Song et al.   STEM CELLS

Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance

(2016) Bangwei Luo et al.   IMMUNITY

Apoptotic adipose-derived mesenchymal stem cell therapy protects against lung and kidney injury in sepsis syndrome caused by cecal ligation puncture in rats

(2014) Pei-Hsun Sung et al.   Stem Cell Research & Therapy

Mesenchymal stem cells ameliorate rhabdomyolysis-induced acute kidney injury via the activation of M2 macrophages

(2014) Yanqiu Geng et al.   Stem Cell Research & Therapy

Iron Administration before Stem Cell Harvest Enables MR Imaging Tracking after Transplantation

(2013) Aman Khurana et al.   RADIOLOGY

Dynamic Imaging of Marrow-Resident Granulocytes Interacting with Human Mesenchymal Stem Cells upon Systemic Lipopolysaccharide Challenge

(2013) Jay T. Myers et al.   Stem Cells International

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Labeling Stem Cells with Ferumoxytol, an FDA-Approved Iron Oxide Nanoparticle

(2011) Rosalinda T. Castaneda et al.   Jove-Journal of Visualized Experiments

Allogeneic mesenchymal stem cells prevent allergic airway inflammation by inducing murine regulatory T cells

(2010) H. Kavanagh et al.   ALLERGY

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE