TRAF3 enhances type I interferon receptor signaling in T cells by modulating the phosphatase PTPN22

Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with TRAF3 mutations

(2022) William Rae et al.   Science Immunology

Multiple mechanisms for TRAF3-mediated regulation of the T cell costimulatory receptor GITR

(2021) Hanzeng Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRAF3 in T Cells Restrains Negative Regulators of LAT to Promote TCR/CD28 Signaling

(2021) Tina Arkee et al.   JOURNAL OF IMMUNOLOGY

Negative regulation of type I IFN signaling

(2018) Kei-Ichiro Arimoto et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tumor Necrosis Factor Receptor-Associated Factor Regulation of Nuclear Factor κB and Mitogen-Activated Protein Kinase Pathways

(2018) Jian-Hong Shi et al.   Frontiers in Immunology

TRAF3 enhances TCR signaling by regulating the inhibitors Csk and PTPN22

(2017) Alicia M. Wallis et al.   Scientific Reports

Nuclear TRAF3 is a negative regulator of CREB in B cells

(2016) Nurbek Mambetsariev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRAF3 deficiency promotes metabolic reprogramming in B cells

(2016) Nurbek Mambetsariev et al.   Scientific Reports

Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling

(2015) Derek A. Holmes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development

(2015) Wai W. Lin et al.   Science Signaling

miR-744 enhances type I interferon signaling pathway by targeting PTP1B in primary human renal mesangial cells

(2015) Xiaoyan Zhang et al.   Scientific Reports

The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development

(2015) Wai W. Lin et al.   Science Signaling

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2

(2014) Zuoan Yi et al.   NATURE IMMUNOLOGY

Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection

(2014) I. Osokine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tyrosine Phosphatase PTPN22: Multifunctional Regulator of Immune Signaling, Development, and Disease

(2013) Nunzio Bottini et al.   Annual Review of Immunology

The Autoimmunity-Associated Gene PTPN22 Potentiates Toll-like Receptor-Driven, Type 1 Interferon-Dependent Immunity

(2013) Yaya Wang et al.   IMMUNITY

TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells

(2013) Zuoan Yi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo

(2013) Gabriel R. Starbeck-Miller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Suppressor of Cytokine Signaling (SOCS) 1 Inhibits Type I Interferon (IFN) Signaling via the Interferon α Receptor (IFNAR1)-associated Tyrosine Kinase Tyk2

(2011) Rebecca A. R. Piganis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes

(2011) Ping Xie et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

TNF Receptor-Associated Factor 3 Is Required for T Cell-Mediated Immunity and TCR/CD28 Signaling

(2010) P. Xie et al.   JOURNAL OF IMMUNOLOGY

Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes

(2009) H. Cheon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA