Refactored genetic codes enable bidirectional genetic isolation

Widespread stop-codon recoding in bacteriophages may regulate translation of lytic genes

(2022) Adair L. Borges et al.   Nature Microbiology

Creating custom synthetic genomes in Escherichia coli with REXER and GENESIS

(2021) Wesley E. Robertson et al.   Nature Protocols

Sense codon reassignment enables viral resistance and encoded polymer synthesis

(2021) Wesley E. Robertson et al.   SCIENCE

Disease variant prediction with deep generative models of evolutionary data

(2021) Jonathan Frazer et al.   NATURE

A computational screen for alternative genetic codes in over 250,000 genomes

(2021) Yekaterina Shulgina et al.   eLife

Viral contamination in biologic manufacture and implications for emerging therapies

(2020) Paul W. Barone et al.   NATURE BIOTECHNOLOGY

Horizontal Gene Transfer as a Source of Conflict and Cooperation in Prokaryotes

(2020) Rebecca J. Hall et al.   Frontiers in Microbiology

How To Quantify a Genetic Firewall? A Polarity‐Based Metric for Genetic Code Engineering

(2020) Markus Schmidt et al.   CHEMBIOCHEM

Reprogramming the genetic code

(2020) Daniel de la Torre et al.   NATURE REVIEWS GENETICS

Total synthesis of Escherichia coli with a recoded genome

(2019) Julius Fredens et al.   NATURE

Fail-safe genetic codes designed to intrinsically contain engineered organisms

(2019) Jonathan Calles et al.   NUCLEIC ACIDS RESEARCH

On universal coding events in protein biogenesis

(2018) Vladimir Kubyshkin et al.   BIOSYSTEMS

Next-generation biocontainment systems for engineered organisms

(2018) Jeong Wook Lee et al.   Nature Chemical Biology

Refactoring the Genetic Code for Increased Evolvability

(2017) Gur Pines et al.   mBio

Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads

(2017) Ryan R. Wick et al.   PLoS Computational Biology

Environmental T4-Family Bacteriophages Evolve to Escape Abortive Infection via Multiple Routes in a Bacterial Host Employing “Altruistic Suicide” through Type III Toxin-Antitoxin Systems

(2017) Bihe Chen et al.   Frontiers in Microbiology

Attenuation of RNA viruses by redirecting their evolution in sequence space

(2017) Gonzalo Moratorio et al.   Nature Microbiology

Defining synonymous codon compression schemes by genome recoding

(2016) Kaihang Wang et al.   NATURE

Erratum: Corrigendum: Biocontainment of genetically modified organisms by synthetic protein design

(2015) Daniel J. Mandell et al.   NATURE

Erratum: Corrigendum: Recoded organisms engineered to depend on synthetic amino acids

(2015) Alexis J. Rovner et al.   NATURE

Horizontal gene transfer: building the web of life

(2015) Shannon M. Soucy et al.   NATURE REVIEWS GENETICS

Engineering reduced evolutionary potential for synthetic biology

(2014) Brian A. Renda et al.   Molecular BioSystems

Natural reassignment of CUU and CUA sense codons to alanine in Ashbya mitochondria

(2013) Jiqiang Ling et al.   NUCLEIC ACIDS RESEARCH

Genomically Recoded Organisms Expand Biological Functions

(2013) M. J. Lajoie et al.   SCIENCE

Virus-host co-evolution under a modified nuclear genetic code

(2013) Derek J. Taylor et al.   PeerJ

Chemical Evolution of a Bacterium’s Genome

(2011) Philippe Marlière et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The genetic code of the fungal CTG clade

(2011) Manuel A.S. Santos et al.   COMPTES RENDUS BIOLOGIES

Origin and evolution of the genetic code: The universal enigma

(2009) Eugene V. Koonin et al.   IUBMB LIFE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Virus Attenuation by Genome-Scale Changes in Codon Pair Bias

(2008) J. R. Coleman et al.   SCIENCE

Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome

(2008) D. G. Gibson et al.   SCIENCE