Sense codon reassignment enables viral resistance and encoded polymer synthesis

Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase–tRNA pairs

(2020) Daniele Cervettini et al.   NATURE BIOTECHNOLOGY

New codons for efficient production of unnatural proteins in a semisynthetic organism

(2020) Emil C. Fischer et al.   Nature Chemical Biology

Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids

(2020) Daniel L. Dunkelmann et al.   Nature Chemistry

Overcoming Near-Cognate Suppression in a Release Factor 1-Deficient Host with an Improved Nitro-Tyrosine tRNA Synthetase

(2020) Jenna N. Beyer et al.   JOURNAL OF MOLECULAR BIOLOGY

Noncanonical Roles of tRNAs: tRNA Fragments and Beyond

(2020) Zhangli Su et al.   Annual Review of Genetics

Reprogramming the genetic code

(2020) Daniel de la Torre et al.   NATURE REVIEWS GENETICS

Retapamulin-Assisted Ribosome Profiling Reveals the Alternative Bacterial Proteome

(2019) Sezen Meydan et al.   MOLECULAR CELL

Mutually orthogonal nonsense-suppression systems and conjugation chemistries for precise protein labeling at up to three distinct sites

(2019) James S Italia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis of Escherichia coli with a recoded genome

(2019) Julius Fredens et al.   NATURE

Playing with the Molecules of Life

(2018) Douglas D. Young et al.   ACS Chemical Biology

Controlling orthogonal ribosome subunit interactions enables evolution of new function

(2018) Wolfgang H. Schmied et al.   NATURE

Expanding and reprogramming the genetic code

(2017) Jason W. Chin   NATURE

A semi-synthetic organism that stores and retrieves increased genetic information

(2017) Yorke Zhang et al.   NATURE

Non-canonical roles of tRNAs and tRNA mimics in bacterial cell biology

(2016) Assaf Katz et al.   MOLECULAR MICROBIOLOGY

Defining synonymous codon compression schemes by genome recoding

(2016) Kaihang Wang et al.   NATURE

Genomic Recoding Broadly Obstructs the Propagation of Horizontally Transferred Genetic Elements

(2016) Natalie Jing Ma et al.   Cell Systems

Rationally evolving tRNAPylfor efficient incorporation of noncanonical amino acids

(2015) Chenguang Fan et al.   NUCLEIC ACIDS RESEARCH

Development of potent in vivo mutagenesis plasmids with broad mutational spectra

(2015) Ahmed H. Badran et al.   Nature Communications

Comprehensive Analysis of Stop Codon Usage in Bacteria and Its Correlation with Release Factor Abundance

(2014) Gürkan Korkmaz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal

(2014) Thomas S Elliott et al.   NATURE BIOTECHNOLOGY

Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET

(2014) Kaihang Wang et al.   Nature Chemistry

Reprogramming the genetic code in vitro

(2014) Toby Passioura et al.   TRENDS IN BIOCHEMICAL SCIENCES

Genomically Recoded Organisms Expand Biological Functions

(2013) M. J. Lajoie et al.   SCIENCE

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Adding New Chemistries to the Genetic Code

(2010) Chang C. Liu et al.   Annual Review of Biochemistry

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

(2010) Heinz Neumann et al.   NATURE

Biopython: freely available Python tools for computational molecular biology and bioinformatics

(2009) P. J. A. Cock et al.   BIOINFORMATICS

Small Stress Response Proteins in Escherichia coli: Proteins Missed by Classical Proteomic Studies

(2009) M. R. Hemm et al.   JOURNAL OF BACTERIOLOGY

Virus stalls Genzyme plant

(2009) Victor Bethencourt   NATURE BIOTECHNOLOGY

Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode Nɛ-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification

(2008) Tatsuo Yanagisawa et al.   CHEMISTRY & BIOLOGY