Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB

microRNAs and Their Roles in Plant Development

(2022) Qingkun Dong et al.   Frontiers in Plant Science

Functional specialization of monocot DCL3 and DCL5 proteins through the evolution of the PAZ domain

(2022) Shirui Chen et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of MicroRNA Biogenesis and Stability Control in Plants

(2022) Lu Zhang et al.   Frontiers in Plant Science

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

RNA structure probing reveals the structural basis of Dicer binding and cleavage

(2021) Qing-Jun Luo et al.   Nature Communications

Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation

(2021) Qian Wang et al.   SCIENCE

Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA

(2020) Alexander C. Partin et al.   MOLECULAR CELL

FARFAR2: Improved De Novo Rosetta Prediction of Complex Global RNA Folds

(2020) Andrew Martin Watkins et al.   STRUCTURE

UCSF ChimeraX : Structure visualization for researchers, educators, and developers

(2020) Eric F. Pettersen et al.   PROTEIN SCIENCE

Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction

(2020) Ali Punjani et al.   NATURE METHODS

Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate

(2018) Zhongmin Liu et al.   CELL

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

Dicer partner protein tunes the length of miRNAs using base-mismatch in the pre-miRNA stem

(2018) Li Zhu et al.   NUCLEIC ACIDS RESEARCH

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Dicer uses distinct modules for recognizing dsRNA termini

(2017) Niladri K. Sinha et al.   SCIENCE

Structure of Human DROSHA

(2016) S. Chul Kwon et al.   CELL

Structural and functional insights into the fly microRNA biogenesis factor Loquacious

(2016) Leonhard Jakob et al.   RNA

TRBP ensures efficient Dicer processing of precursor microRNA in RNA-crowded environments

(2016) Mohamed Fareh et al.   Nature Communications

Revealing a new activity of the human Dicer DUF283 domain in vitro

(2016) Anna Kurzynska-Kokorniak et al.   Scientific Reports

The Drosophila Dicer-1 Partner Loquacious Enhances miRNA Processing from Hairpins with Unstable Structures at the Dicing Site

(2016) Mandy Yu Theng Lim et al.   Cell Reports

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Dicer-TRBP Complex Formation Ensures Accurate Mammalian MicroRNA Biogenesis

(2015) Ross C. Wilson et al.   MOLECULAR CELL

Crystal Structure Studies of RNA Duplexes Containing s2U:A and s2U:U Base Pairs

(2014) Jia Sheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer

(2014) Yuan Tian et al.   MOLECULAR CELL

‘Black sheep’ that don’t leave the double-stranded RNA-binding domain fold

(2014) Michael L. Gleghorn et al.   TRENDS IN BIOCHEMICAL SCIENCES

RNase III: Genetics and Function; Structure and Mechanism

(2013) Donald L. Court et al.   Annual Review of Genetics

ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing

(2013) Hiromitsu Ota et al.   CELL

Substrate-specific structural rearrangements of human Dicer

(2013) David W Taylor et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribonuclease III mechanisms of double-stranded RNA cleavage

(2013) Allen W. Nicholson   Wiley Interdisciplinary Reviews-RNA

The Loop Position of shRNAs and Pre-miRNAs Is Critical for the Accuracy of Dicer Processing In Vivo

(2012) Shuo Gu et al.   CELL

Dicer Partner Proteins Tune the Length of Mature miRNAs in Flies and Mammals

(2012) Ryuya Fukunaga et al.   CELL

The molecular architecture of human Dicer

(2012) Pick-Wei Lau et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs

(2012) A. M. Gurtan et al.   RNA

Phosphate and R2D2 Restrict the Substrate Specificity of Dicer-2, an ATP-Driven Ribonuclease

(2011) Elif Sarinay Cenik et al.   MOLECULAR CELL

Dicer recognizes the 5′ end of RNA for efficient and accurate processing

(2011) Jong-Eun Park et al.   NATURE

Recognition of the pre-miRNA structure by Drosophila Dicer-1

(2011) Akihisa Tsutsumi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

(2010) H. R. Chiang et al.   GENES & DEVELOPMENT

Structure of the Arabidopsis thaliana DCL4 DUF283 domain reveals a noncanonical double-stranded RNA-binding fold for protein-protein interaction

(2010) H. Qin et al.   RNA

Structure of Arabidopsis HYPONASTIC LEAVES1 and Its Molecular Implications for miRNA Processing

(2010) Seong Wook Yang et al.   STRUCTURE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Small RNAs and Their Roles in Plant Development

(2009) Xuemei Chen   Annual Review of Cell and Developmental Biology

Characterization of the TRBP domain required for Dicer interaction and function in RNA interference

(2009) Sylvanne M Daniels et al.   BMC MOLECULAR BIOLOGY

Structural determinants of miRNAs for RISC loading and slicer-independent unwinding

(2009) Tomoko Kawamata et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural insights into RNA processing by the human RISC-loading complex

(2009) Hong-Wei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Human Dicer-TRBP Complex by Electron Microscopy

(2009) Pick-Wei Lau et al.   STRUCTURE

Heterodimer-based analysis of subunit and domain contributions to double-stranded RNA processing byEscherichia coliRNase IIIin vitro

(2008) Wenzhao Meng et al.   BIOCHEMICAL JOURNAL