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Title
Focus on your locus with a massively parallel reporter assay
Authors
Keywords
-
Journal
Journal of Neurodevelopmental Disorders
Volume 14, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-09-10
DOI
10.1186/s11689-022-09461-x
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- (2022) Islam Oguz Tuncay et al. npj Genomic Medicine
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- (2022) Nathan S. Abell et al. SCIENCE
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- (2021) Rachel E. Rodin et al. NATURE NEUROSCIENCE
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- (2021) Julie Jerber et al. NATURE GENETICS
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- (2021) Kazuhiko Sawada et al. PLoS One
- Regulatory role of long non coding RNAs (lncRNAs) in neurological disorders: From novel biomarkers to promising therapeutic strategies
- (2021) Nirjhar Bhattacharyya et al. Asian Journal of Pharmaceutical Sciences
- Genome-wide functional screen of 3′UTR variants uncovers causal variants for human disease and evolution
- (2021) Dustin Griesemer et al. CELL
- Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation
- (2021) Dan Liang et al. NATURE NEUROSCIENCE
- CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis
- (2021) Julian D. Gillmore et al. NEW ENGLAND JOURNAL OF MEDICINE
- Advances in profiling chromatin architecture shed light on the regulatory dynamics underlying brain disorders
- (2021) Brandon M. Pratt et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders
- (2021) Benxia Hu et al. Nature Communications
- Transcriptional-regulatory convergence across functional MDD risk variants identified by massively parallel reporter assays
- (2021) Bernard Mulvey et al. Translational Psychiatry
- Towards a comprehensive catalogue of validated and target-linked human enhancers
- (2020) Molly Gasperini et al. NATURE REVIEWS GENETICS
- Candidate silencer elements for the human and mouse genomes
- (2020) Naresh Doni Jayavelu et al. Nature Communications
- Distinct long non-coding RNA and mRNA expression profiles in the hippocampus of an attention deficit hyperactivity disorder model in spontaneously hypertensive rats and control wistar Kyoto rats
- (2020) SufenZhang et al. BRAIN RESEARCH BULLETIN
- A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles
- (2020) Nancy Y. A. Sey et al. NATURE NEUROSCIENCE
- Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma
- (2020) Jiyeon Choi et al. Nature Communications
- Association study of a single nucleotide polymorphism in brain cytoplasmic 200 long-noncoding RNA and psychiatric disorders
- (2020) Mir Salar Kahaei et al. METABOLIC BRAIN DISEASE
- lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements
- (2020) M. Grace Gordon et al. Nature Protocols
- Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants
- (2020) Siwei Zhang et al. SCIENCE
- Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism
- (2020) Nana Matoba et al. Translational Psychiatry
- Interpreting the impact of noncoding structural variation in neurodevelopmental disorders
- (2020) Eva D’haene et al. GENETICS IN MEDICINE
- Cas9 gene therapy for Angelman syndrome traps Ube3a-ATS long non-coding RNA
- (2020) Justin M. Wolter et al. NATURE
- A systematic evaluation of the design and context dependencies of massively parallel reporter assays
- (2020) Jason C. Klein et al. NATURE METHODS
- Non-coding structural variation differentially impacts attention-deficit hyperactivity disorder (ADHD) gene networks in African American vs Caucasian children
- (2020) Yichuan Liu et al. Scientific Reports
- Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen
- (2020) Hao Zhang et al. eLife
- Regulatory landscape in brain development and disease
- (2020) Keeley Spiess et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders
- (2019) Cheen Euong Ang et al. eLife
- Long Non-coding RNA in Neuronal Development and Neurological Disorders
- (2019) Ling Li et al. Frontiers in Genetics
- Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases
- (2019) Marco Cavalli et al. Scientific Reports
- The three-dimensional landscape of the genome in human brain tissue unveils regulatory mechanisms leading to schizophrenia risk
- (2019) Won Mah et al. SCHIZOPHRENIA RESEARCH
- Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders
- (2019) Patrick F. Sullivan et al. CELL
- Whole genome sequencing and variant discovery in the ASPIRE autism spectrum disorder cohort
- (2019) D. Benjamin Callaghan et al. CLINICAL GENETICS
- Epigenomic Convergence of Neural-Immune Risk Factors in Neurodevelopmental Disorder Cortex
- (2019) A Vogel Ciernia et al. CEREBRAL CORTEX
- Human 5′ UTR design and variant effect prediction from a massively parallel translation assay
- (2019) Paul J. Sample et al. NATURE BIOTECHNOLOGY
- Deciphering regulatory DNA sequences and noncoding genetic variants using neural network models of massively parallel reporter assays
- (2019) Rajiv Movva et al. PLoS One
- A screen of 1,049 schizophrenia and 30 Alzheimer's‐associated variants for regulatory potential
- (2019) Leslie Myint et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks
- (2019) Elizabeth K. Ruzzo et al. CELL
- Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction
- (2019) Fumitaka Inoue et al. Cell Stem Cell
- Neurobiological functions of transcriptional enhancers
- (2019) Alex S. Nord et al. NATURE NEUROSCIENCE
- Brain cell type–specific enhancer–promoter interactome maps and disease-risk association
- (2019) Alexi Nott et al. SCIENCE
- Maternal valproic acid exposure leads to neurogenesis defects and autism-like behaviors in non-human primates
- (2019) Hui Zhao et al. Translational Psychiatry
- The Role of Non-Coding RNAs in Neurodevelopmental Disorders
- (2019) Shuang-Feng Zhang et al. Frontiers in Genetics
- Deciphering eukaryotic gene-regulatory logic with 100 million random promoters
- (2019) Carl G. de Boer et al. NATURE BIOTECHNOLOGY
- Understanding Neurodevelopmental Disorders: The Promise of Regulatory Variation in the 3′UTRome
- (2018) Kai A. Wanke et al. BIOLOGICAL PSYCHIATRY
- Role of non-coding RNAs in non-aging-related neurological disorders
- (2018) A.S. Vieira et al. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
- The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis
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- High‐throughput identification of RNA nuclear enrichment sequences
- (2018) Chinmay J Shukla et al. EMBO JOURNAL
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- (2018) Y. Jung et al. GENES BRAIN AND BEHAVIOR
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- (2018) Eric Courchesne et al. MOLECULAR PSYCHIATRY
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- (2018) Julia di Iulio et al. NATURE GENETICS
- Genetic identification of brain cell types underlying schizophrenia
- (2018) Nathan G. Skene et al. NATURE GENETICS
- An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder
- (2018) Donna M. Werling et al. NATURE GENETICS
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- (2018) Daniel J. Schaid et al. NATURE REVIEWS GENETICS
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- (2018) Palle Duun Rohde et al. G3-Genes Genomes Genetics
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- (2018) Yichuan Liu et al. Translational Psychiatry
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- (2018) Brett B Maricque et al. NATURE BIOTECHNOLOGY
- Widespread RNA editing dysregulation in brains from autistic individuals
- (2018) Stephen S. Tran et al. NATURE NEUROSCIENCE
- Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder
- (2018) Joon-Yong An et al. SCIENCE
- The DGCR5 long noncoding RNA may regulate expression of several schizophrenia-related genes
- (2018) Qingtuan Meng et al. Science Translational Medicine
- The Role of De Novo Noncoding Regulatory Mutations in Neurodevelopmental Disorders
- (2018) Tychele N. Turner et al. TRENDS IN NEUROSCIENCES
- TRUB1 is the predominant pseudouridine synthase acting on mammalian mRNA via a predictable and conserved code
- (2017) Modi Safra et al. GENOME RESEARCH
- Molecular mechanisms underlying noncoding risk variations in psychiatric genetic studies
- (2017) X Xiao et al. MOLECULAR PSYCHIATRY
- Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
- (2017) Julia Joung et al. Nature Protocols
- Integrative genomic analyses for identification and prioritization of long non-coding RNAs associated with autism
- (2017) Brian L. Gudenas et al. PLoS One
- Global analysis of protein folding using massively parallel design, synthesis, and testing
- (2017) Gabriel J. Rocklin et al. SCIENCE
- Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses
- (2017) Amirhossein Modabbernia et al. Molecular Autism
- FINEMAP: efficient variable selection using summary data from genome-wide association studies
- (2016) Christian Benner et al. BIOINFORMATICS
- Sort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relations
- (2016) Neil Peterman et al. BMC GENOMICS
- Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex
- (2016) Xiaochang Zhang et al. CELL
- Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
- (2016) Atray Dixit et al. CELL
- Familial Dysautonomia: Mechanisms and Models
- (2016) Paula Dietrich et al. GENETICS AND MOLECULAR BIOLOGY
- High-throughput functional comparison of promoter and enhancer activities
- (2016) Thomas A. Nguyen et al. GENOME RESEARCH
- In Utero Exposure to Valproic Acid Induces Neocortical Dysgenesis via Dysregulation of Neural Progenitor Cell Proliferation/Differentiation
- (2016) Kimino Fujimura et al. JOURNAL OF NEUROSCIENCE
- Altered proliferation and networks in neural cells derived from idiopathic autistic individuals
- (2016) M C Marchetto et al. MOLECULAR PSYCHIATRY
- Dissecting the genetics of complex traits using summary association statistics
- (2016) Bogdan Pasaniuc et al. NATURE REVIEWS GENETICS
- The Cellular and Molecular Landscapes of the Developing Human Central Nervous System
- (2016) John C. Silbereis et al. NEURON
- STARR-seq — Principles and applications
- (2015) Felix Muerdter et al. GENOMICS
- Decoding enhancers using massively parallel reporter assays
- (2015) Fumitaka Inoue et al. GENOMICS
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- The role of regulatory variation in complex traits and disease
- (2015) Frank W. Albert et al. NATURE REVIEWS GENETICS
- Genome-wide differential expression of synaptic long noncoding RNAs in autism spectrum disorder
- (2015) Y Wang et al. Translational Psychiatry
- Exploring the function of genetic variants in the non-coding genomic regions: approaches for identifying human regulatory variants affecting gene expression
- (2014) M. J. Li et al. BRIEFINGS IN BIOINFORMATICS
- Identifying Causal Variants at Loci with Multiple Signals of Association
- (2014) F. Hormozdiari et al. GENETICS
- Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes
- (2014) Jason D Buenrostro et al. NATURE BIOTECHNOLOGY
- A Role for Noncoding Variation in Schizophrenia
- (2014) Panos Roussos et al. Cell Reports
- Mining the 3′UTR of Autism-implicated Genes for SNPs Perturbing MicroRNA Regulation
- (2014) Varadharajan Vaishnavi et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- Fetal antiepileptic drug exposure: Adaptive and emotional/behavioral functioning at age 6years
- (2013) Morris J. Cohen et al. EPILEPSY & BEHAVIOR
- Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism
- (2013) Jakob Christensen et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- In utero exposure to valproic acid and autism — A current review of clinical and animal studies
- (2013) Florence I. Roullet et al. NEUROTOXICOLOGY AND TERATOLOGY
- Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model
- (2013) Paolo Petazzi et al. RNA Biology
- Aberrant Expression of Long Noncoding RNAs in Autistic Brain
- (2012) Mark N. Ziats et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression
- (2012) Gabsang Lee et al. NATURE BIOTECHNOLOGY
- Use of ADHD drugs in the Nordic countries: a population-based comparison study
- (2010) H. Zoëga et al. ACTA PSYCHIATRICA SCANDINAVICA
- Functions and Regulation of RNA Editing by ADAR Deaminases
- (2010) Kazuko Nishikura Annual Review of Biochemistry
- Valproic Acid Monotherapy in Pregnancy and Major Congenital Malformations
- (2010) Janneke Jentink et al. NEW ENGLAND JOURNAL OF MEDICINE
- Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
- (2009) Gabsang Lee et al. NATURE
- High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis
- (2009) Rupali P Patwardhan et al. NATURE BIOTECHNOLOGY
- ChIP–seq: advantages and challenges of a maturing technology
- (2009) Peter J. Park NATURE REVIEWS GENETICS
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