The role of regulatory variation in complex traits and disease

Identification and Validation of Genetic Variants that Influence Transcription Factor and Cell Signaling Protein Levels

(2014) Ronald J. Hause et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An Enhancer Polymorphism at the Cardiomyocyte Intercalated Disc Protein NOS1AP Locus Is a Major Regulator of the QT Interval

(2014) Ashish Kapoor et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cross-Tissue and Tissue-Specific eQTLs: Partitioning the Heritability of a Complex Trait

(2014) Jason M. Torres et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

(2014) Alexander Gusev et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Joint Analysis of Functional Genomic Data and Genome-wide Association Studies of 18 Human Traits

(2014) Joseph K. Pickrell   AMERICAN JOURNAL OF HUMAN GENETICS

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Genetics of gene expression in immunity to infection

(2014) Benjamin P Fairfax et al.   CURRENT OPINION IN IMMUNOLOGY

Genetic Architecture of Ethanol-Responsive Transcriptome Variation in Saccharomyces cerevisiae Strains

(2014) Jeffrey A. Lewis et al.   GENETICS

Influence of Gene Interaction on Complex Trait Variation with Multilocus Models

(2014) Asko Mäki-Tanila et al.   GENETICS

Genetic Influences on Brain Gene Expression in Rats Selected for Tameness and Aggression

(2014) H. O. Heyne et al.   GENETICS

Heritability and genetic basis of protein level variation in an outbred population

(2014) Leopold Parts et al.   GENOME RESEARCH

Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C

(2014) Nicola H. Dryden et al.   GENOME RESEARCH

Extensive and coordinated control of allele-specific expression by both transcription and translation in Candida albicans

(2014) D. Muzzey et al.   GENOME RESEARCH

Determining causality and consequence of expression quantitative trait loci

(2014) A. Battle et al.   HUMAN GENETICS

Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types

(2014) Qiyuan Li et al.   HUMAN MOLECULAR GENETICS

Natural genetic variation impacts expression levels of coding, non-coding, and antisense transcripts in fission yeast

(2014) M. Clement-Ziza et al.   Molecular Systems Biology

Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs

(2014) V. Adoue et al.   Molecular Systems Biology

Detection and replication of epistasis influencing transcription in humans

(2014) Gibran Hemani et al.   NATURE

Genetics of single-cell protein abundance variation in large yeast populations

(2014) Frank W. Albert et al.   NATURE

Another explanation for apparent epistasis

(2014) Andrew R. Wood et al.   NATURE

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

(2014) Barbara Treutlein et al.   NATURE

Obesity-associated variants within FTO form long-range functional connections with IRX3

(2014) Scott Smemo et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

CRISPR-Cas systems for editing, regulating and targeting genomes

(2014) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins

(2014) Alfonso Buil et al.   NATURE GENETICS

A molecular basis for classic blond hair color in Europeans

(2014) Catherine A Guenther et al.   NATURE GENETICS

Heritability and genomics of gene expression in peripheral blood

(2014) Fred A Wright et al.   NATURE GENETICS

Genetic variability in the regulation of gene expression in ten regions of the human brain

(2014) Adaikalavan Ramasamy et al.   NATURE NEUROSCIENCE

Investigating human disease using stem cell models

(2014) Jared L. Sterneckert et al.   NATURE REVIEWS GENETICS

Evolution of transcription factor binding in metazoans — mechanisms and functional implications

(2014) Diego Villar et al.   NATURE REVIEWS GENETICS

A Bayesian Method to Incorporate Hundreds of Functional Characteristics with Association Evidence to Improve Variant Prioritization

(2014) Sarah A. Gagliano et al.   PLoS One

Genome-Wide Identification of Expression Quantitative Trait Loci (eQTLs) in Human Heart

(2014) Tamara T. Koopmann et al.   PLoS One

Interindividual variation in human T regulatory cells

(2014) A. Ferraro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of regulatory variation from RNA to protein

(2014) A. Battle et al.   SCIENCE

Intersection of population variation and autoimmunity genetics in human T cell activation

(2014) C. J. Ye et al.   SCIENCE

Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes

(2014) T. Raj et al.   SCIENCE

Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells

(2014) M. N. Lee et al.   SCIENCE

Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression

(2014) B. P. Fairfax et al.   SCIENCE

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

(2014) D. A. Jaitin et al.   SCIENCE

Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes

(2014) Sarah Kim et al.   Nature Communications

Harnessing Natural Sequence Variation to Dissect Posttranscriptional Regulatory Networks in Yeast

(2014) Mina Fazlollahi et al.   G3-Genes Genomes Genetics

Quantitative Genetics of CTCF Binding Reveal Local Sequence Effects and Different Modes of X-Chromosome Association

(2014) Zhihao Ding et al.   PLoS Genetics

Single Nucleotide Variants in Transcription Factors Associate More Tightly with Phenotype than with Gene Expression

(2014) Priya Sudarsanam et al.   PLoS Genetics

GPA: A Statistical Approach to Prioritizing GWAS Results by Integrating Pleiotropy and Annotation

(2014) Dongjun Chung et al.   PLoS Genetics

Cis and Trans Effects of Human Genomic Variants on Gene Expression

(2014) Julien Bryois et al.   PLoS Genetics

Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels

(2014) Nicholas E. Banovich et al.   PLoS Genetics

Genetic Dissection of the Drosophila melanogaster Female Head Transcriptome Reveals Widespread Allelic Heterogeneity

(2014) Elizabeth G. King et al.   PLoS Genetics

Genetic Influences on Translation in Yeast

(2014) Frank W. Albert et al.   PLoS Genetics

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

Integrating Functional Data to Prioritize Causal Variants in Statistical Fine-Mapping Studies

(2014) Gleb Kichaev et al.   PLoS Genetics

Genetic Background Drives Transcriptional Variation in Human Induced Pluripotent Stem Cells

(2014) Foad Rouhani et al.   PLoS Genetics

Contribution of genetic variation to transgenerational inheritance of DNA methylation

(2014) Allan F McRae et al.   GENOME BIOLOGY

System wide analyses have underestimated protein abundances and the importance of transcription in mammals

(2014) Jingyi Jessica Li et al.   PeerJ

Genetic and Epigenetic Regulation of Human lincRNA Gene Expression

(2013) Konstantin Popadin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors

(2013) Chuan Gao et al.   BIOINFORMATICS

Accounting for non-genetic factors by low-rank representation and sparse regression for eQTL mapping

(2013) Can Yang et al.   BIOINFORMATICS

Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci

(2013) Qiyuan Li et al.   CELL

Genetic and Nongenetic Variation Revealed for the Principal Components of Human Gene Expression

(2013) Anita Goldinger et al.   GENETICS

DNA methylation contributes to natural human variation

(2013) H. Heyn et al.   GENOME RESEARCH

The genetic basis for individual differences in mRNA splicing and APOBEC1 editing activity in murine macrophages

(2013) M. A. Hassan et al.   GENOME RESEARCH

Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast

(2013) D. A. Skelly et al.   GENOME RESEARCH

Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals

(2013) A. Battle et al.   GENOME RESEARCH

Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits

(2013) Mete Civelek et al.   HUMAN MOLECULAR GENETICS

Effect of natural genetic variation on enhancer selection and function

(2013) S. Heinz et al.   NATURE

The effects of genetic variation on gene expression dynamics during development

(2013) Mirko Francesconi et al.   NATURE

A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis

(2013) Paola Picotti et al.   NATURE

Variation and genetic control of protein abundance in humans

(2013) Linfeng Wu et al.   NATURE

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

(2013) Lara M. Mangravite et al.   NATURE

Transcriptome and genome sequencing uncovers functional variation in humans

(2013) Tuuli Lappalainen et al.   NATURE

Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories

(2013) Peter A C 't Hoen et al.   NATURE BIOTECHNOLOGY

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Systems genetics approaches to understand complex traits

(2013) Mete Civelek et al.   NATURE REVIEWS GENETICS

Expression Quantitative Trait Locus Mapping across Water Availability Environments Reveals Contrasting Associations with Genomic Features in Arabidopsis

(2013) D. B. Lowry et al.   PLANT CELL

Normalizing RNA-Sequencing Data by Modeling Hidden Covariates with Prior Knowledge

(2013) Sara Mostafavi et al.   PLoS One

Identification of genetic variants influencing the human plasma proteome

(2013) A. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensive Variation in Chromatin States Across Humans

(2013) M. Kasowski et al.   SCIENCE

Coordinated Effects of Sequence Variation on DNA Binding, Chromatin Structure, and Transcription

(2013) H. Kilpinen et al.   SCIENCE

Identification of Genetic Variants That Affect Histone Modifications in Human Cells

(2013) G. McVicker et al.   SCIENCE

The Molecular Mechanism of a Cis-Regulatory Adaptation in Yeast

(2013) Jessica Chang et al.   PLoS Genetics

Robust Prediction of Expression Differences among Human Individuals Using Only Genotype Information

(2013) Ohad Manor et al.   PLoS Genetics

A Statistical Framework for Joint eQTL Analysis in Multiple Tissues

(2013) Timothée Flutre et al.   PLoS Genetics

Genetic Landscape of Open Chromatin in Yeast

(2013) Kibaick Lee et al.   PLoS Genetics

Global Properties and Functional Complexity of Human Gene Regulatory Variation

(2013) Daniel J. Gaffney   PLoS Genetics

Integrative Modeling of eQTLs and Cis-Regulatory Elements Suggests Mechanisms Underlying Cell Type Specificity of eQTLs

(2013) Christopher D. Brown et al.   PLoS Genetics

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

(2013) Vinod Kumar et al.   PLoS Genetics

Impact of Natural Genetic Variation on Gene Expression Dynamics

(2013) Marit Ackermann et al.   PLoS Genetics

All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs

(2013) Andrew J. Schork et al.   PLoS Genetics

Genotype-Environment Interactions Reveal Causal Pathways That Mediate Genetic Effects on Phenotype

(2013) Julien Gagneur et al.   PLoS Genetics

Integrative genomic analysis of the human immune response to influenza vaccination

(2013) Luis M Franco et al.   eLife

Expression variation in connected recombinant populations of Arabidopsis thaliana highlights distinct transcriptome architectures

(2012) Francisco A Cubillos et al.   BMC GENOMICS

Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans

(2012) Sarah R. Langley et al.   CARDIOVASCULAR RESEARCH

Unraveling Inflammatory Responses using Systems Genetics and Gene-Environment Interactions in Macrophages

(2012) Luz D. Orozco et al.   CELL

Quantitative Trait Loci Mapping of the Mouse Plasma Proteome (pQTL)

(2012) L. M. Holdt et al.   GENETICS

Functional Genomic Architecture of Predisposition to Voluntary Exercise in Mice: Expression QTL in the Brain

(2012) S. A. Kelly et al.   GENETICS

Effects of sequence variation on differential allelic transcription factor occupancy and gene expression

(2012) T. E. Reddy et al.   GENOME RESEARCH

Linking disease associations with regulatory information in the human genome

(2012) M. A. Schaub et al.   GENOME RESEARCH

Identification of cis-regulatory variation influencing protein abundance levels in human plasma

(2012) Anbarasu Lourdusamy et al.   HUMAN MOLECULAR GENETICS

Nonlinear Fitness Consequences of Variation in Expression Level of a Eukaryotic Gene

(2012) J. S. Rest et al.   MOLECULAR BIOLOGY AND EVOLUTION

The promise of induced pluripotent stem cells in research and therapy

(2012) Daisy A. Robinton et al.   NATURE

DNase I sensitivity QTLs are a major determinant of human expression variation

(2012) Jacob F. Degner et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

The accessible chromatin landscape of the human genome

(2012) Robert E. Thurman et al.   NATURE

Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles

(2012) Benjamin P Fairfax et al.   NATURE GENETICS

Chromatin marks identify critical cell types for fine mapping complex trait variants

(2012) Gosia Trynka et al.   NATURE GENETICS

Mapping cis- and trans-regulatory effects across multiple tissues in twins

(2012) Elin Grundberg et al.   NATURE GENETICS

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

(2012) Oliver Stegle et al.   Nature Protocols

The Brisbane Systems Genetics Study: Genetical Genomics Meets Complex Trait Genetics

(2012) Joseph E. Powell et al.   PLoS One

Using Prior Information from the Medical Literature in GWAS of Oral Cancer Identifies Novel Susceptibility Variant on Chromosome 4 - the AdAPT Method

(2012) Mattias Johansson et al.   PLoS One

Powerful Identification of Cis-regulatory SNPs in Human Primary Monocytes Using Allele-Specific Gene Expression

(2012) Jonas Carlsson Almlöf et al.   PLoS One

Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection

(2012) L. B. Barreiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mice Lacking a Myc Enhancer That Includes Human SNP rs6983267 Are Resistant to Intestinal Tumors

(2012) I. K. Sur et al.   SCIENCE

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

Joint Modelling of Confounding Factors and Prominent Genetic Regulators Provides Increased Accuracy in Genetical Genomics Studies

(2012) Nicoló Fusi et al.   PLoS Computational Biology

Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

(2012) Ke Hao et al.   PLoS Genetics

The Contribution of RNA Decay Quantitative Trait Loci to Inter-Individual Variation in Steady-State Gene Expression Levels

(2012) Athma A. Pai et al.   PLoS Genetics

Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants

(2012) Fanggeng Zou et al.   PLoS Genetics

Genomic Variation and Its Impact on Gene Expression in Drosophila melanogaster

(2012) Andreas Massouras et al.   PLoS Genetics

Extent, Causes, and Consequences of Small RNA Expression Variation in Human Adipose Tissue

(2012) Leopold Parts et al.   PLoS Genetics

Dissecting the regulatory architecture of gene expression QTLs

(2012) Daniel J Gaffney et al.   GENOME BIOLOGY

Genome-wide expression quantitative trait loci (eQTL) analysis in maize

(2011) Beth Holloway et al.   BMC GENOMICS

Genetic analysis of complex traits in the emerging Collaborative Cross

(2011) David L. Aylor et al.   GENOME RESEARCH

Temporal dynamics and genetic control of transcription in the human prefrontal cortex

(2011) Carlo Colantuoni et al.   NATURE

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

(2011) Olivier Harismendy et al.   NATURE

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes

(2011) Kerrin S Small et al.   NATURE GENETICS

Using Functional Annotation for the Empirical Determination of Bayes Factors for Genome-Wide Association Study Analysis

(2011) Jo Knight et al.   PLoS One

Genetic Variation Shapes Protein Networks Mainly through Non-transcriptional Mechanisms

(2011) Eric J. Foss et al.   PLOS BIOLOGY

Global Analysis of the Impact of Environmental Perturbation on cis-Regulation of Gene Expression

(2011) Elin Grundberg et al.   PLoS Genetics

Rare and Common Regulatory Variation in Population-Scale Sequenced Human Genomes

(2011) Stephen B. Montgomery et al.   PLoS Genetics

Single-Tissue and Cross-Tissue Heritability of Gene Expression Via Identity-by-Descent in Related or Unrelated Individuals

(2011) Alkes L. Price et al.   PLoS Genetics

Joint Genetic Analysis of Gene Expression Data with Inferred Cellular Phenotypes

(2011) Leopold Parts et al.   PLoS Genetics

Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue

(2011) Federico Innocenti et al.   PLoS Genetics

Integrating Genome-Wide Genetic Variations and Monocyte Expression Data Reveals Trans-Regulated Gene Modules in Humans

(2011) Maxime Rotival et al.   PLoS Genetics

Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA

(2011) Rudolf S. N. Fehrmann et al.   PLoS Genetics

Comparative Analysis of Proteome and Transcriptome Variation in Mouse

(2011) Anatole Ghazalpour et al.   PLoS Genetics

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

(2011) Jordana T Bell et al.   GENOME BIOLOGY

Differential Contributions of Rare and Common, Coding and Noncoding Ret Mutations to Multifactorial Hirschsprung Disease Liability

(2010) Eileen Sproat Emison et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Expression Quantitative Trait Loci: Replication, Tissue- and Sex-Specificity in Mice

(2010) A. van Nas et al.   GENETICS

Identification of Quantitative Trait Loci Underlying Proteome Variation in Human Lymphoblastoid Cells

(2010) Nikhil Garge et al.   MOLECULAR & CELLULAR PROTEOMICS

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

(2010) Matthias Heinig et al.   NATURE

Transcriptome genetics using second generation sequencing in a Caucasian population

(2010) Stephen B. Montgomery et al.   NATURE

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE

Understanding mechanisms underlying human gene expression variation with RNA sequencing

(2010) Joseph K. Pickrell et al.   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Tackling the widespread and critical impact of batch effects in high-throughput data

(2010) Jeffrey T. Leek et al.   NATURE REVIEWS GENETICS

The genetic basis of evolutionary change in gene expression levels

(2010) J. J. Emerson et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

(2010) Tanja Zeller et al.   PLoS One

Correction for hidden confounders in the genetic analysis of gene expression

(2010) J. Listgarten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variation in Transcription Factor Binding Among Humans

(2010) M. Kasowski et al.   SCIENCE

Selection at Linked Sites Shapes Heritable Phenotypic Variation in C. elegans

(2010) M. V. Rockman et al.   SCIENCE

Heritable Individual-Specific and Allele-Specific Chromatin Signatures in Humans

(2010) R. McDaniell et al.   SCIENCE

A Bayesian Framework to Account for Complex Non-Genetic Factors in Gene Expression Levels Greatly Increases Power in eQTL Studies

(2010) Oliver Stegle et al.   PLoS Computational Biology

Noisy Splicing Drives mRNA Isoform Diversity in Human Cells

(2010) Joseph K. Pickrell et al.   PLoS Genetics

Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations

(2010) Alexandra C. Nica et al.   PLoS Genetics

Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

(2010) J. Raphael Gibbs et al.   PLoS Genetics

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

Inherited Variation in Gene Expression

(2009) Daniel A. Skelly et al.   Annual Review of Genomics and Human Genetics

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

System-wide molecular evidence for phenotypic buffering in Arabidopsis

(2009) Jingyuan Fu et al.   NATURE GENETICS

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

(2009) Mark M Pomerantz et al.   NATURE GENETICS

Mapping complex disease traits with global gene expression

(2009) William Cookson et al.   NATURE REVIEWS GENETICS

Genetic Interactions Between Transcription Factors Cause Natural Variation in Yeast

(2009) J. Gerke et al.   SCIENCE

Paternal Dominance of Trans-eQTL Influences Gene Expression Patterns in Maize Hybrids

(2009) R. A. Swanson-Wagner et al.   SCIENCE

Common Regulatory Variation Impacts Gene Expression in a Cell Type-Dependent Manner

(2009) A. S. Dimas et al.   SCIENCE

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Expression Quantitative Trait Loci Are Highly Sensitive to Cellular Differentiation State

(2009) Alice Gerrits et al.   PLoS Genetics

Learning a Prior on Regulatory Potential from eQTL Data

(2009) Su-In Lee et al.   PLoS Genetics

Accurate Discovery of Expression Quantitative Trait Loci Under Confounding From Spurious and Genuine Regulatory Hotspots

(2008) H. M. Kang et al.   GENETICS

Variations in DNA elucidate molecular networks that cause disease

(2008) Yanqing Chen et al.   NATURE

Genetics of gene expression and its effect on disease

(2008) Valur Emilsson et al.   NATURE

Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

(2008) Jun Zhu et al.   NATURE GENETICS

Gene–Environment Interaction in Yeast Gene Expression

(2008) Erin N Smith et al.   PLOS BIOLOGY

Mapping the Genetic Architecture of Gene Expression in Human Liver

(2008) Eric E Schadt et al.   PLOS BIOLOGY

A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs)

(2008) David Melzer et al.   PLoS Genetics

Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits

(2008) William G. Hill et al.   PLoS Genetics