Long Non-coding RNA in Neuronal Development and Neurological Disorders

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

REST, a master transcriptional regulator in neurodegenerative disease

(2018) Jee-Yeon Hwang et al.   CURRENT OPINION IN NEUROBIOLOGY

Noncoding RNAs in disease

(2018) Evangelia Lekka et al.   FEBS LETTERS

lncRNA PAPAS tethered to the rDNA enhancer recruits hypophosphorylated CHD4/NuRD to repress rRNA synthesis at elevated temperatures

(2018) Zhongliang Zhao et al.   GENES & DEVELOPMENT

Histone demethylase JMJD1A promotes colorectal cancer growth and metastasis by enhancing Wnt/β-catenin signaling

(2018) Kesong Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long non-coding RNA ASBEL promotes osteosarcoma cell proliferation, migration, and invasion by regulating microRNA-21

(2018) Jianhui Zhao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Osmotic stress-responsive promoter upstream transcripts (PROMPTs) act as carriers of MYB transcription factors to induce the expression of target genes in Populus simonii

(2018) Yuepeng Song et al.   PLANT BIOTECHNOLOGY JOURNAL

Strategies to Annotate and Characterize Long Noncoding RNAs: Advantages and Pitfalls

(2018) Huifen Cao et al.   TRENDS IN GENETICS

Silencing of the lncRNA Zeb2-NAT facilitates reprogramming of aged fibroblasts and safeguards stem cell pluripotency

(2018) Bruno Bernardes de Jesus et al.   Nature Communications

The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain

(2018) Ivelisse Cajigas et al.   MOLECULAR CELL

Down-regulation of lncTCF7 inhibits cell migration and invasion in colorectal cancer via inhibiting TCF7 expression

(2018) Baihe Wu et al.   Human Cell

Genomic origin and nuclear localization of TERRA telomeric repeat-containing RNA: from Darkness to Dawn

(2017) Aurélie Diman et al.   FEBS Journal

Histone methylase MLL1 coordinates with HIF and regulate lncRNA HOTAIR expression under hypoxia

(2017) Arunoday Bhan et al.   GENE

Evolving Notions of Schizophrenia as a Developmental Neurocognitive Disorder

(2017) Larry J. Seidman et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

lncRNA HOXD-AS1 Regulates Proliferation and Chemo-Resistance of Castration-Resistant Prostate Cancer via Recruiting WDR5

(2017) Peng Gu et al.   MOLECULAR THERAPY

Long non-coding RNA LINK-A promotes glioma cell growth and invasion via lactate dehydrogenase A

(2017) Dejun Wu et al.   ONCOLOGY REPORTS

The Diversity of Long Noncoding RNAs and Their Generation

(2017) Huang Wu et al.   TRENDS IN GENETICS

Long non-coding RNA PARTICLE bridges histone and DNA methylation

(2017) Valerie Bríd O’Leary et al.   Scientific Reports

Transcriptional and Post-transcriptional Gene Regulation by Long Non-coding RNA

(2017) Iain M. Dykes et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Changes in the level of Long Non-Coding RNA Gomafu gene expression in schizophrenia patients before and after antipsychotic medication

(2017) Yansong Liu et al.   SCHIZOPHRENIA RESEARCH

Upregulation of SNHG6 regulates ZEB1 expression by competitively binding miR-101-3p and interacting with UPF1 in hepatocellular carcinoma

(2016) Lei Chang et al.   CANCER LETTERS

Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins

(2016) Sungyul Lee et al.   CELL

TUG1: a pivotal oncogenic long non-coding RNA of human cancers

(2016) Zheng Li et al.   CELL PROLIFERATION

Investigation of Long Non-coding RNA Expression Profiles in the Substantia Nigra of Parkinson’s Disease

(2016) Yaohui Ni et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The functions of long noncoding RNAs in development and stem cells

(2016) Rotem Ben-Tov Perry et al.   DEVELOPMENT

HOTTIP: a critical oncogenic long non-coding RNA in human cancers

(2016) Yifan Lian et al.   Molecular BioSystems

The Role of Long Noncoding RNAs in Neurodegenerative Diseases

(2016) Peixing Wan et al.   MOLECULAR NEUROBIOLOGY

Altered Long Noncoding RNA Expression Precedes the Course of Parkinson’s Disease—a Preliminary Report

(2016) Theo F. J. Kraus et al.   MOLECULAR NEUROBIOLOGY

Altered Expression of the Long Noncoding RNA NEAT1 in Huntington’s Disease

(2016) Jun-Sang Sunwoo et al.   MOLECULAR NEUROBIOLOGY

Long non-coding RNA SNHG5 suppresses gastric cancer progression by trapping MTA2 in the cytosol

(2016) L Zhao et al.   ONCOGENE

The Trans-Spliced Long Noncoding RNA tsRMST Impedes Human Embryonic Stem Cell Differentiation Through WNT5A-Mediated Inhibition of the Epithelial-to-Mesenchymal Transition

(2016) Chun-Ying Yu et al.   STEM CELLS

Linking Long Noncoding RNA Localization and Function

(2016) Ling-Ling Chen   TRENDS IN BIOCHEMICAL SCIENCES

Aberrant Expression of Long Non-Coding RNAs in Schizophrenia Patients

(2016) Shengdong Chen et al.   MEDICAL SCIENCE MONITOR

Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer

(2016) Yiwen Fang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

The Circular RNA Cdr1as Act as an Oncogene in Hepatocellular Carcinoma through Targeting miR-7 Expression

(2016) Lei Yu et al.   PLoS One

dbEM: A database of epigenetic modifiers curated from cancerous and normal genomes

(2016) Jagpreet Singh Nanda et al.   Scientific Reports

Long Non-coding RNA H19 Inhibits Adipocyte Differentiation of Bone Marrow Mesenchymal Stem Cells through Epigenetic Modulation of Histone Deacetylases

(2016) Yiping Huang et al.   Scientific Reports

A Cytoplasmic NF-κB Interacting Long Noncoding RNA Blocks IκB Phosphorylation and Suppresses Breast Cancer Metastasis

(2015) Bodu Liu et al.   CANCER CELL

LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration

(2015) Lijun Wang et al.   CELL RESEARCH

Opposing Roles for the lncRNA Haunt and Its Genomic Locus in Regulating HOXA Gene Activation during Embryonic Stem Cell Differentiation

(2015) Yafei Yin et al.   Cell Stem Cell

Long Non-Coding RNA Urothelial Carcinoma Associated 1 (UCA1): Insight into Its Role in Human Diseases

(2015) Feng Li et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Long Noncoding RNA MALAT1: Insights into its Biogenesis and Implications in Human Disease

(2015) Yuting Wu et al.   CURRENT PHARMACEUTICAL DESIGN

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

The emerging role of lncRNAs in cancer

(2015) Maite Huarte   NATURE MEDICINE

RNA transcribed from a distal enhancer is required for activating the chromatin at the promoter of the gonadotropin α-subunit gene

(2015) Lilach Pnueli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNAPCA3

(2015) Ahmad Salameh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relationships between PROMPT and gene expression

(2015) Marta Lloret-Llinares et al.   RNA Biology

Control of Chromatin Structure by Long Noncoding RNA

(2015) Gudrun Böhmdorfer et al.   TRENDS IN CELL BIOLOGY

The Landscape of long noncoding RNA classification

(2015) Georges St. Laurent et al.   TRENDS IN GENETICS

Expression analysis of the long non-coding RNA antisense to Uchl1 (AS Uchl1) during dopaminergic cells' differentiation in vitro and in neurochemical models of Parkinson's disease

(2015) Claudia Carrieri et al.   Frontiers in Cellular Neuroscience

Epigenetic modifiers in normal and malignant hematopoiesis

(2015) Jessica N Haladyna et al.   Epigenomics

Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA

(2015) Michele Scarola et al.   Nature Communications

Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition

(2015) Tong-Hong Wang et al.   Oncotarget

The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation

(2015) Fan Yang et al.   GENOME BIOLOGY

Genome-wide differential expression of synaptic long noncoding RNAs in autism spectrum disorder

(2015) Y Wang et al.   Translational Psychiatry

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1

(2015) Andrew E. Tee et al.   Oncotarget

Noncoding RNAs and Epigenetic Mechanisms During X-Chromosome Inactivation

(2014) Anne-Valerie Gendrel et al.   Annual Review of Cell and Developmental Biology

X-marks the spot: X-chromosome identification during dosage compensation

(2014) Jessica Chery et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

lncRNA Directs Cooperative Epigenetic Regulation Downstream of Chemokine Signals

(2014) Zhen Xing et al.   CELL

The long non-coding RNA Paupar regulates the expression of both local and distal genes

(2014) K. W. Vance et al.   EMBO JOURNAL

Identification, stability and expression of Sirt1 antisense long non-coding RNA

(2014) Yu Wang et al.   GENE

LincRNA-p21 Activates p21 In cis to Promote Polycomb Target Gene Expression and to Enforce the G1/S Checkpoint

(2014) Nadya Dimitrova et al.   MOLECULAR CELL

Functional Consequences of Splicing of the Antisense Transcript COOLAIR on FLC Transcription

(2014) Sebastian Marquardt et al.   MOLECULAR CELL

An atlas of active enhancers across human cell types and tissues

(2014) Robin Andersson et al.   NATURE

The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease

(2014) T. C. Roberts et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A New lncRNA, APTR, Associates with and Represses the CDKN1A/p21 Promoter by Recruiting Polycomb Proteins

(2014) Masamitsu Negishi et al.   PLoS One

Genomic Imprinting in Mammals

(2014) D. P. Barlow et al.   Cold Spring Harbor Perspectives in Biology

Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit

(2014) Pavan Kumar Puvvula et al.   Nature Communications

The long non-coding RNA Dali is an epigenetic regulator of neural differentiation

(2014) Vladislava Chalei et al.   eLife

Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease

(2014) Brian S. Clark et al.   Frontiers in Genetics

X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease

(2013) Jeannie T. Lee et al.   CELL

Jpx RNA Activates Xist by Evicting CTCF

(2013) Sha Sun et al.   CELL

Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment

(2013) Carla A. Klattenhoff et al.   CELL

Integration of Genome-wide Approaches Identifies lncRNAs of Adult Neural Stem Cells and Their Progeny In Vivo

(2013) Alexander D. Ramos et al.   Cell Stem Cell

Developmental Changes in the Transcriptome of Human Cerebral Cortex Tissue: Long Noncoding RNA Transcripts

(2013) Leonard Lipovich et al.   CEREBRAL CORTEX

Evf2 (Dlx6as) lncRNA regulates ultraconserved enhancer methylation and the differential transcriptional control of adjacent genes

(2013) E. G. Berghoff et al.   DEVELOPMENT

Endogenous miRNA Sponge lincRNA-RoR Regulates Oct4, Nanog, and Sox2 in Human Embryonic Stem Cell Self-Renewal

(2013) Yue Wang et al.   DEVELOPMENTAL CELL

The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse

(2013) Phillip Grote et al.   DEVELOPMENTAL CELL

ANRIL: Molecular Mechanisms and Implications in Human Health

(2013) Ada Congrains et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MALAT1 — a paradigm for long noncoding RNA function in cancer

(2013) Tony Gutschner et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Circular Intronic Long Noncoding RNAs

(2013) Yang Zhang et al.   MOLECULAR CELL

The Long Noncoding RNA RMST Interacts with SOX2 to Regulate Neurogenesis

(2013) Shi-Yan Ng et al.   MOLECULAR CELL

lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs

(2013) Liuqing Yang et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts

(2013) Sarah Geisler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TINCR, staufen1, and cellular differentiation

(2013) Markus Kretz   RNA Biology

Long Noncoding RNAs: New Players in the Molecular Mechanism for Maintenance and Differentiation of Pluripotent Stem Cells

(2013) Suman Ghosal et al.   STEM CELLS AND DEVELOPMENT

Long noncoding RNAs in development and disease of the central nervous system

(2013) Shi-Yan Ng et al.   TRENDS IN GENETICS

Aberrant Expression of Long Noncoding RNAs in Autistic Brain

(2012) Mark N. Ziats et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat

(2012) Claudia Carrieri et al.   NATURE

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation

(2012) Farzaneh Modarresi et al.   NATURE BIOTECHNOLOGY

The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r

(2012) Andrew Keniry et al.   NATURE CELL BIOLOGY

Airn Transcriptional Overlap, But Not Its lncRNA Products, Induces Imprinted Igf2r Silencing

(2012) P. A. Latos et al.   SCIENCE

No-Nonsense Functions for Long Noncoding RNAs

(2011) Takashi Nagano et al.   CELL

Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors

(2011) Shi-Yan Ng et al.   EMBO JOURNAL

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

The KCNQ1OT1 imprinting control region and non-coding RNA: new properties derived from the study of Beckwith–Wiedemann syndrome and Silver–Russell syndrome cases

(2011) Nicoletta Chiesa et al.   HUMAN MOLECULAR GENETICS

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Functions of Noncoding RNAs in Neural Development and Neurological Diseases

(2011) Shan Bian et al.   MOLECULAR NEUROBIOLOGY

lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3′ UTRs via Alu elements

(2011) Chenguang Gong et al.   NATURE

The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity

(2011) Nicole A Rapicavoli et al.   Neural Development

Long non-coding RNAs in Huntington's disease neurodegeneration

(2011) Rory Johnson   NEUROBIOLOGY OF DISEASE

A Transcriptomic Atlas of Mouse Neocortical Layers

(2011) T. Grant Belgard et al.   NEURON

PROMoter uPstream Transcripts share characteristics with mRNAs and are produced upstream of all three major types of mammalian promoters

(2011) Pascal Preker et al.   NUCLEIC ACIDS RESEARCH

Functional variants ofTSPAN8are associated with bipolar disorder and schizophrenia

(2010) Claus-Jürgen Scholz et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation

(2010) Tim R Mercer et al.   BMC NEUROSCIENCE

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

(2010) Vidisha Tripathi et al.   MOLECULAR CELL

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

(2010) Sabine Loewer et al.   NATURE GENETICS

Human accelerated region 1 noncoding RNA is repressed by REST in Huntington's disease

(2010) Rory Johnson et al.   PHYSIOLOGICAL GENOMICS

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Noncoding RNA Gas5 Is a Growth Arrest- and Starvation-Associated Repressor of the Glucocorticoid Receptor

(2010) T. Kino et al.   Science Signaling

Evidence for natural antisense transcript-mediated inhibition of microRNA function

(2010) Mohammad Ali Faghihi et al.   GENOME BIOLOGY

Evolution and Functions of Long Noncoding RNAs

(2009) Chris P. Ponting et al.   CELL

TERRA: telomeric repeat-containing RNA

(2009) Brian Luke et al.   EMBO JOURNAL

An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles

(2009) Christine M. Clemson et al.   MOLECULAR CELL

Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry

(2009) Allison M Bond et al.   NATURE NEUROSCIENCE

Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells

(2009) J. Sheik Mohamed et al.   RNA

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

(2008) Mohammad Ali Faghihi et al.   NATURE MEDICINE