The Disordered MAX N-terminus Modulates DNA Binding of the Transcription Factor MYC:MAX

Estimation of Effective Concentrations Enforced by Complex Linker Architectures from Conformational Ensembles

(2022) Magnus Kjaergaard   BIOCHEMISTRY

Negatively charged disordered regions are prevalent and functionally important across proteomes

(2022) Lavi S. Bigman et al.   JOURNAL OF MOLECULAR BIOLOGY

FOXO4 Transactivation Domain Interaction with Forkhead DNA Binding Domain and Effect on Selective DNA Recognition for Transcription Initiation

(2021) Jinwoo Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

Dynamic Autoinhibition of the HMGB1 Protein via Electrostatic Fuzzy Interactions of Intrinsically Disordered Regions

(2021) Xi Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

Multiple regulatory intrinsically disordered motifs control FOXO4 transcription factor binding and function

(2021) Benjamin Bourgeois et al.   Cell Reports

Structural and Biophysical Insights into the Function of the Intrinsically Disordered Myc Oncoprotein

(2020) Marie-Eve Beaulieu et al.   Cells

Intrinsically Disordered Regions Direct Transcription Factor In Vivo Binding Specificity

(2020) Sagie Brodsky et al.   MOLECULAR CELL

Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA

(2019) Susan Sammak et al.   BIOCHEMISTRY

Methyl TROSY spectroscopy: A versatile NMR approach to study challenging biological systems

(2019) Stefan Schütz et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Effective concentrations enforced by intrinsically disordered linkers are governed by polymer physics

(2019) Charlotte S. Sørensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-range regulation of p53 DNA binding by its intrinsically disordered N-terminal transactivation domain

(2018) Alexander S. Krois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs

(2017) Michael Allevato et al.   PLoS One

Biophysical characterization of the b-HLH-LZ of ΔMax, an alternatively spliced isoform of Max found in tumor cells: Towards the validation of a tumor suppressor role for the Max homodimers

(2017) Loïka Maltais et al.   PLoS One

CcpNmr AnalysisAssign: a flexible platform for integrated NMR analysis

(2016) Simon P. Skinner et al.   JOURNAL OF BIOMOLECULAR NMR

Miz-1 and Max compete to engage c-Myc: implication for the mechanism of inhibition of c-Myc transcriptional activity by Miz-1

(2016) Mikaël Bédard et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Myc and its interactors take shape

(2015) William B. Tu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis

(2014) Arianna Sabò et al.   NATURE

MYC Phosphorylation at Novel Regulatory Regions Suppresses Transforming Activity

(2013) A. R. Wasylishen et al.   CANCER RESEARCH

Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity

(2013) Q. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using chemical shift perturbation to characterise ligand binding

(2013) Mike P. Williamson   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding

(2012) Cecilia Andresen et al.   NUCLEIC ACIDS RESEARCH

The Max b-HLH-LZ Can Transduce into Cells and Inhibit c-Myc Transcriptional Activities

(2012) Martin Montagne et al.   PLoS One

Kinetic Analysis of the Interaction of b/HLH/Z Transcription Factors Myc, Max, and Mad with Cognate DNA

(2010) Ozgur Ecevit et al.   BIOCHEMISTRY

CCAAT/Enhancer-binding Protein β DNA Binding Is Auto-inhibited by Multiple Elements That Also Mediate Association with p300/CREB-binding Protein (CBP)

(2010) Sook Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA

(2009) T. Sekiya et al.   GENES & DEVELOPMENT

Interaction between the Transactivation Domain of p53 and PC4 Exemplifies Acidic Activation Domains as Single-stranded DNA Mimics

(2009) Sridharan Rajagopalan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prediction of Xaa-Pro peptide bond conformation from sequence and chemical shifts

(2009) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

The Max homodimeric b-HLH-LZ significantly interferes with the specific heterodimerization between the c-Myc and Max b-HLH-LZ in absence of DNA: a quantitative analysis

(2009) François-Olivier McDuff et al.   JOURNAL OF MOLECULAR RECOGNITION

Biochemical and Structural Characterization of an Intramolecular Interaction in FOXO3a and Its Binding with p53

(2008) Feng Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

A One Pot, One Step, Precision Cloning Method with High Throughput Capability

(2008) Carola Engler et al.   PLoS One