Negatively charged disordered regions are prevalent and functionally important across proteomes

Release of linker histone from the nucleosome driven by polyelectrolyte competition with a disordered protein

(2022) Pétur O. Heidarsson et al.   Nature Chemistry

Biophysics of Phase Separation of Disordered Proteins Is Governed by Balance between Short- And Long-Range Interactions

(2021) Milan Kumar Hazra et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Polyampholyte physics: Liquid–liquid phase separation and biological condensates

(2021) Jelena Dinic et al.   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

Intrinsically disordered electronegative clusters improve stability and binding specificity of RNA-binding proteins

(2021) Steve Zaharias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Autoinhibition of the HMGB1 Protein via Electrostatic Fuzzy Interactions of Intrinsically Disordered Regions

(2021) Xi Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

DAXX represents a new type of protein-folding enabler

(2021) Liangqian Huang et al.   NATURE

flDPnn: Accurate intrinsic disorder prediction with putative propensities of disorder functions

(2021) Gang Hu et al.   Nature Communications

Ribosome Elongation Kinetics of Consecutively Charged Residues Are Coupled to Electrostatic Force

(2021) Sarah E. Leininger et al.   BIOCHEMISTRY

Protein Diffusion on Charged Biopolymers: DNA versus Microtubule

(2020) Lavi S. Bigman et al.   BIOPHYSICAL JOURNAL

Tubulin tails and their modifications regulate protein diffusion on microtubules

(2020) Lavi S. Bigman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relevance of Electrostatic Charges in Compactness, Aggregation, and Phase Separation of Intrinsically Disordered Proteins

(2020) Greta Bianchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intramolecular electrostatic interactions contribute to phospholipase Cβ3 autoinhibition

(2019) Candi M. Esquina et al.   CELLULAR SIGNALLING

Binding without folding – the biomolecular function of disordered polyelectrolyte complexes

(2019) Benjamin Schuler et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding

(2018) Bálint Mészáros et al.   NUCLEIC ACIDS RESEARCH

Long-range regulation of p53 DNA binding by its intrinsically disordered N-terminal transactivation domain

(2018) Alexander S. Krois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Internal Associations of the Acidic Region of Upstream Binding Factor Control Its Nucleolar Localization

(2017) Shuhei Ueshima et al.   MOLECULAR AND CELLULAR BIOLOGY

The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease

(2016) M. Madan Babu   BIOCHEMICAL SOCIETY TRANSACTIONS

Disordered nucleiome: Abundance of intrinsic disorder in the DNA- and RNA-binding proteins in 1121 species from Eukaryota, Bacteria and Archaea

(2016) Chen Wang et al.   PROTEOMICS

The Tail That Wags the Dog: How the Disordered C-Terminal Domain Controls the Transcriptional Activities of the p53 Tumor-Suppressor Protein

(2016) Oleg Laptenko et al.   TRENDS IN BIOCHEMICAL SCIENCES

Relating sequence encoded information to form and function of intrinsically disordered proteins

(2015) Rahul K Das et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structural D/E-rich repeats play multiple roles especially in gene regulation through DNA/RNA mimicry

(2015) Chia-Cheng Chou et al.   Molecular BioSystems

Intrinsically Disordered Proteins and Intrinsically Disordered Protein Regions

(2014) Christopher J. Oldfield et al.   Annual Review of Biochemistry

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

The most important thing is the tail: Multitudinous functionalities of intrinsically disordered protein termini

(2013) Vladimir N. Uversky   FEBS LETTERS

Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues

(2013) R. K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy

(2012) H. Hofmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsically disordered regions as affinity tuners in protein–DNA interactions

(2011) Dana Vuzman et al.   Molecular BioSystems

Occurrence of disordered patterns and homorepeats in eukaryotic and bacterial proteomes

(2011) M. Yu. Lobanov et al.   Molecular BioSystems

Net charge per residue modulates conformational ensembles of intrinsically disordered proteins

(2010) A. H. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA search efficiency is modulated by charge composition and distribution in the intrinsically disordered tail

(2010) D. Vuzman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Charge interactions can dominate the dimensions of intrinsically disordered proteins

(2010) S. Muller-Spath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Searching DNA via a “Monkey Bar” Mechanism: The Significance of Disordered Tails

(2009) Dana Vuzman et al.   JOURNAL OF MOLECULAR BIOLOGY

Electrostatics in the Ribosomal Tunnel Modulate Chain Elongation Rates

(2008) Jianli Lu et al.   JOURNAL OF MOLECULAR BIOLOGY