Gut microbiota and myocardial fibrosis

Exploring blood microbial communities and their influence on human cardiovascular disease

(2022) Ikram Khan et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Dynamic modulation of gut microbiota improves post‐myocardial infarct tissue repair in rats via butyric acid‐mediated histone deacetylase inhibition

(2021) Tongtong Song et al.   FASEB JOURNAL

Changes of gut microbiome composition and metabolites associated with hypertensive heart failure rats

(2021) Lin Li et al.   BMC MICROBIOLOGY

Gut microbiota dysbiosis promotes age-related atrial fibrillation by lipopolysaccharide and glucose-induced activation of NLRP3-inflammasome

(2021) Yun Zhang et al.   CARDIOVASCULAR RESEARCH

Dysbiosis of Gut Microbiota in Patients With Acute Myocardial Infarction

(2021) Ying Han et al.   Frontiers in Microbiology

Transmethylamine‐N‐Oxide Is Associated With Diffuse Cardiac Fibrosis in People Living With HIV

(2021) Nalini A. Colaco et al.   Journal of the American Heart Association

Attenuation of Circulating Trimethylamine N-Oxide Prevents the Progression of Cardiac and Renal Dysfunction in a Rat Model of Chronic Cardiorenal Syndrome

(2021) Deling Zou et al.   Frontiers in Pharmacology

Acute Coronary Syndromes and Inflammatory Bowel Disease: The Gut–Heart Connection

(2021) Ayman Jaaouani et al.   Journal of Clinical Medicine

Darm-Herz-Achse

(2020) Hendrik Bartolomaeus et al.   HERZ

Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells

(2020) Qi Yan Ang et al.   CELL

Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease

(2020) David M. Kaye et al.   CIRCULATION

Nonlethal Inhibition of Gut Microbial Trimethylamine N‐oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure

(2020) Chelsea L. Organ et al.   Journal of the American Heart Association

Gut Microbiota‐Dependent Trimethylamine N‐oxide and Cardiovascular Outcomes in Patients With Prior Myocardial Infarction: A Nested Case Control Study From the PEGASUS‐TIMI 54 Trial

(2020) Baris Gencer et al.   Journal of the American Heart Association

Butyrate-producing bacteria and the gut-heart axis in atherosclerosis

(2020) Wujun Chen et al.   CLINICA CHIMICA ACTA

Probiotics Supplementation on Cardiac Remodeling Following Myocardial Infarction: a Single-Center Double-Blind Clinical Study

(2020) Jalal Moludi et al.   Journal of Cardiovascular Translational Research

Gut microbiota remodeling reverses aging-associated inflammation and dysregulation of systemic bile acid homeostasis in mice sex-specifically

(2020) Junli Ma et al.   Gut Microbes

Neuregulin-1 Induces Cardiac Hypertrophy and Impairs Cardiac Performance in Post–Myocardial Infarction Rats

(2020) Magdalena Zurek et al.   CIRCULATION

Ketogenic diet attenuates aging-associated myocardial remodeling and dysfunction in mice

(2020) Yunhua Yu et al.   EXPERIMENTAL GERONTOLOGY

TMAO: how gut microbiota contributes to heart failure

(2020) Yixin Zhang et al.   Translational Research

The Short-Chain Fatty Acid Propionate Protects from Hypertensive Cardiovascular Damage

(2019) Hendrik Bartolomaeus et al.   CIRCULATION

Loss of Gut Microbiota Alters Immune System Composition and Cripples Post-Infarction Cardiac Repair

(2019) Tony WH Tang et al.   CIRCULATION

Trimethylamine N-oxide and risk of heart failure progression: marker or mediator of disease

(2019) Ovidiu Chioncel et al.   EUROPEAN JOURNAL OF HEART FAILURE

Gut microbiota and hypertension

(2019) Jun-ichi Oyama et al.   HYPERTENSION RESEARCH

Gut microbiota regulates cardiac ischemic tolerance and aortic stiffness in obesity

(2019) Micah L. Battson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Transfer of a healthy microbiota reduces amyloid and tau pathology in an Alzheimer’s disease animal model

(2019) Min-Soo Kim et al.   GUT

Gut microbe-derived metabolite trimethylamine N-oxide accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis

(2019) Wenlong Yang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Trimethylamine N-Oxide Exacerbates Cardiac Fibrosis via Activating the NLRP3 Inflammasome

(2019) Xueling Li et al.   Frontiers in Physiology

Luhong Granules Prevent Ventricular Remodelling after Myocardial Infarction by Reducing the Metabolites TMAO and LPS of the Intestinal Flora

(2019) Tianshu Yang et al.   Evidence-based Complementary and Alternative Medicine

Effect of Diet on the Gut Microbiota: Rethinking Intervention Duration

(2019) Emily R Leeming et al.   Nutrients

Harms Reporting in Randomized Controlled Trials of Interventions Aimed at Modifying Microbiota

(2018) Aïda Bafeta et al.   ANNALS OF INTERNAL MEDICINE

Trimethylamine N-oxide promotes atherosclerosis via CD36-dependent MAPK/JNK pathway

(2018) Jin Geng et al.   BIOMEDICINE & PHARMACOTHERAPY

The Fragility of Probiotic Bifidobacterium longum NCC3001 Use for Depression in Patients With Irritable Bowel Syndrome

(2018) Chase Meyer et al.   GASTROENTEROLOGY

Metagenomic and metabolomic analyses unveil dysbiosis of gut microbiota in chronic heart failure patients

(2018) Xiao Cui et al.   Scientific Reports

CHRONIC, LOW-DOSE TMAO TREATMENT REDUCES DIASTOLIC DYSFUNCTION AND HEART FIBROSIS IN HYPERTENSIVE RATS.

(2018) Tomasz Huc et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

With Probiotics, Resistance Is Not Always Futile

(2018) Christopher J. Severyn et al.   Cell Host & Microbe

Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis

(2018) Zehua Li et al.   LABORATORY INVESTIGATION

Human gut bacteria as potent class I histone deacetylase inhibitors in vitro through production of butyric acid and valeric acid

(2018) Samantha Yuille et al.   PLoS One

The gut microbiome and heart failure

(2018) Adilah F. Ahmad et al.   CURRENT OPINION IN CARDIOLOGY

Dietary metabolism, the gut microbiome, and heart failure

(2018) W. H. Wilson Tang et al.   Nature Reviews Cardiology

Fecal microbiota transplantation alleviates myocardial damage in myocarditis by restoring the microbiota composition

(2018) Xiao-Fan Hu et al.   PHARMACOLOGICAL RESEARCH

Probiotics and Child Care Absence Due to Infections: A Randomized Controlled Trial

(2017) Rikke Pilmann Laursen et al.   PEDIATRICS

The gut microbiome in atherosclerotic cardiovascular disease

(2017) Zhuye Jie et al.   Nature Communications

Moderate-Intensity Exercise Affects Gut Microbiome Composition and Influences Cardiac Function in Myocardial Infarction Mice

(2017) Zuheng Liu et al.   Frontiers in Microbiology

Trimethylamine N-oxide Supplementation Abolishes the Cardioprotective Effects of Voluntary Exercise in Mice Fed a Western Diet

(2017) Hongqi Zhang et al.   Frontiers in Physiology

Gut Microbiota-Dependent Metabolite Trimethylamine N-Oxide Contributes to Cardiac Dysfunction in Western Diet-Induced Obese Mice

(2017) Kui Chen et al.   Frontiers in Physiology

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive MiceClinical Perspective

(2016) Francine Z. Marques et al.   CIRCULATION

Multi-Strain Probiotics Inhibit Cardiac Myopathies and Autophagy to Prevent Heart Injury in High-Fat Diet-Fed Rats

(2016) Chao-Hung Lai et al.   International Journal of Medical Sciences

The Human Intestinal Microbiome in Health and Disease

(2016) Susan V. Lynch et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Gut Feeling about Thrombosis

(2016) Herbert Tilg   NEW ENGLAND JOURNAL OF MEDICINE

Effects of the Mediterranean Diet on Cardiovascular Outcomes—A Systematic Review and Meta-Analysis

(2016) Thaminda Liyanage et al.   PLoS One

Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice

(2015) Youfang Chen et al.   Cardiovascular Diabetology

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

(2015) Zeneng Wang et al.   CELL

Choline Diet and Its Gut Microbe–Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload–Induced Heart FailureCLINICAL PERSPECTIVE

(2015) Chelsea L. Organ et al.   Circulation-Heart Failure

Probiotic therapy with Saccharomyces boulardii for heart failure patients: A randomized, double-blind, placebo-controlled pilot trial

(2015) Annelise C. Costanza et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Chronic high fat diet induces cardiac hypertrophy and fibrosis in mice

(2015) Zhi Wang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Probiotic supplementation and trimethylamine-N-oxide production following a high-fat diet

(2015) Nabil E. Boutagy et al.   Obesity

Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine- N -Oxide

(2015) Kymberleigh A. Romano et al.   mBio

Probiotic Administration Attenuates Myocardial Hypertrophy and Heart Failure After Myocardial Infarction in the Rat

(2014) Xiaohong Tracey Gan et al.   Circulation-Heart Failure

Transmission of Atherosclerosis Susceptibility with Gut Microbial Transplantation

(2014) Jill C. Gregory et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure

(2014) W.H. Wilson Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Myocardial Fibrosis Induced by Exposure to Subclinical Lipopolysaccharide Is Associated with Decreased miR-29c and Enhanced NOX2 Expression in Mice

(2014) Wilbur Y. W. Lew et al.   PLoS One

The pathogenesis of cardiac fibrosis

(2013) Ping Kong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Early short-term doxycycline therapy in patients with acute myocardial infarction and left ventricular dysfunction to prevent the ominous progression to adverse remodelling: the TIPTOP trial

(2013) G. Cerisano et al.   EUROPEAN HEART JOURNAL

Western lifestyle: a ‘master’ manipulator of the intestinal microbiota?

(2013) Georgina L Hold   GUT

A decrease of the butyrate-producing speciesRoseburia hominisandFaecalibacterium prausnitziidefines dysbiosis in patients with ulcerative colitis

(2013) Kathleen Machiels et al.   GUT

Recurrent Exposure to Subclinical Lipopolysaccharide Increases Mortality and Induces Cardiac Fibrosis in Mice

(2013) Wilbur Y. W. Lew et al.   PLoS One

Fiber and Prebiotics: Mechanisms and Health Benefits

(2013) Joanne Slavin   Nutrients

Structural Remodeling and Mechanical Function in Heart Failure

(2012) Bridget Louise Leonard et al.   MICROSCOPY AND MICROANALYSIS

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

IBD—what role do Proteobacteria play?

(2012) Indrani Mukhopadhya et al.   Nature Reviews Gastroenterology & Hepatology

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

(2012) S. Craciun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Dynamic interactions between the cellular components of the heart and the extracellular matrix

(2011) Thomas K. Borg et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Doxycycline Attenuates Isoproterenol-Induced Myocardial Fibrosis and Matrix Metalloproteinase Activity in Rats

(2009) Yasutomo Hori et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Cardiac Fibroblast

(2009) Colby A. Souders et al.   CIRCULATION RESEARCH

The myofibroblast: Paradigm for a mechanically active cell

(2009) Boris Hinz   JOURNAL OF BIOMECHANICS

Extracellular matrix profiles in the progression to heart failure

(2008) H. K. Graham et al.   Acta Physiologica