Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis

Gut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis

(2017) Gabriele Giacomo Schiattarella et al.   EUROPEAN HEART JOURNAL

Hypertension in rats is associated with an increased permeability of the colon to TMA, a gut bacteria metabolite

(2017) Kinga Jaworska et al.   PLoS One

Transforming growth factor β and its role in heart disease

(2017) Guangwang Liu et al.   Experimental and Therapeutic Medicine

The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis

(2016) Karolina Skagen et al.   ATHEROSCLEROSIS

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

Hypertension-Linked Pathophysiological Alterations in the GutNovelty and Significance

(2016) Monica M. Santisteban et al.   CIRCULATION RESEARCH

Gut hormones and gut microbiota: implications for kidney function and hypertension

(2016) Baris Afsar et al.   Journal of the American Society of Hypertension

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Theo Vos et al.   LANCET

Gut Microbiota Promote Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction

(2016) Susanne H. Karbach et al.   Journal of the American Heart Association

Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB

(2016) Marcus M. Seldin et al.   Journal of the American Heart Association

Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control

(2015) Daniel M. Mueller et al.   ATHEROSCLEROSIS

Choline Diet and Its Gut Microbe–Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload–Induced Heart FailureCLINICAL PERSPECTIVE

(2015) Chelsea L. Organ et al.   Circulation-Heart Failure

Intersections Between Microbiome and Heart Failure: Revisiting the Gut Hypothesis

(2015) Yuji Nagatomo et al.   JOURNAL OF CARDIAC FAILURE

Intestinal Microbiota-Dependent Phosphatidylcholine Metabolites, Diastolic Dysfunction, and Adverse Clinical Outcomes in Chronic Systolic Heart Failure

(2015) W.H. Wilson Tang et al.   JOURNAL OF CARDIAC FAILURE

Impact of Gut Microbiota on Obesity, Diabetes, and Cardiovascular Disease Risk

(2015) Luca Miele et al.   Current Cardiology Reports

Alteration of Cardiac ACE2/Mas Expression and Cardiac Remodelling in Rats with Aortic Constriction

(2015) Yanling Zhang   CHINESE JOURNAL OF PHYSIOLOGY

Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry

(2014) Zeneng Wang et al.   ANALYTICAL BIOCHEMISTRY

Comparative Genome-Wide Association Studies in Mice and Humans for Trimethylamine N -Oxide, a Proatherogenic Metabolite of Choline and l -Carnitine

(2014) Jaana Hartiala et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure

(2014) W.H. Wilson Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Gut Feelings About Heart Failure∗

(2014) Jane A. Cannon et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Resveratrol ameliorates cardiac dysfunction induced by pressure overload in rats via structural protection and modulation of Ca2+ cycling proteins

(2014) Qi Dong et al.   Journal of Translational Medicine

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE