Aprepitant exerts anti-fibrotic effect via inhibition of TGF-β/Smad3 pathway in bleomycin-induced pulmonary fibrosis in rats

Aprepitant: an antiemetic drug, contributes to the prevention of acute lung injury with its anti-inflammatory and antioxidant properties

(2021) Duygu Kose et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

PM2.5 and water-soluble components induce airway fibrosis through TGF-β1/Smad3 signaling pathway in asthmatic rats

(2021) Hongyan Wu et al.   MOLECULAR IMMUNOLOGY

Carnosol attenuates bleomycin-induced lung damage via suppressing fibrosis, oxidative stress and inflammation in rats

(2021) Hadi Kalantar et al.   LIFE SCIENCES

A Novel Sustained Anti-Inflammatory Effect of Atorvastatin—Calcium PLGA Nanoparticles: In Vitro Optimization and In Vivo Evaluation

(2021) Dalia Abdelkader et al.   Pharmaceutics

TGF-β Signaling

(2020) Kalliopi Tzavlaki et al.   Biomolecules

Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis

(2020) Wei-Chih Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IL-37 Attenuates Lung Fibrosis by Inducing Autophagy and Regulating TGF-β1 Production in Mice

(2019) Mi So Kim et al.   JOURNAL OF IMMUNOLOGY

Cryptotanshinone protects against pulmonary fibrosis through inhibiting Smad and STAT3 signaling pathways

(2019) Yuting Zhang et al.   PHARMACOLOGICAL RESEARCH

Lysine-specific demethylase-1 regulates fibroblast activation in pulmonary fibrosis via TGF-β1/Smad3 pathway

(2019) Xiaohua Pan et al.   PHARMACOLOGICAL RESEARCH

Transcription factor specificity protein 1 modulates TGFβ1/Smad signaling to negatively regulate SIGIRR expression by human M1 macrophages stimulated with substance P

(2018) Rui Yamaguchi et al.   CYTOKINE

Interleukin-37 Attenuates Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice

(2018) Yan Li et al.   INFLAMMATION

A fully automated image analysis method to quantify lung fibrosis in the bleomycin-induced rat model

(2018) Shanon Seger et al.   PLoS One

Doxorubicin-Induced Myocardial Fibrosis Involves the Neurokinin-1 Receptor and Direct Effects on Cardiac Fibroblasts

(2018) Scott P. Levick et al.   Heart Lung and Circulation

Idiopathic pulmonary fibrosis

(2017) Luca Richeldi et al.   LANCET

Longitudinal assessment of bleomycin-induced lung fibrosis by Micro-CT correlates with histological evaluation in mice

(2017) Francesca Ruscitti et al.   MULTIDISCIPLINARY RESPIRATORY MEDICINE

Idiopathic pulmonary fibrosis

(2017) Fernando J. Martinez et al.   Nature Reviews Disease Primers

Pitfalls in the analysis of the physiological antioxidant glutathione (GSH) and its disulfide (GSSG) in biological samples: An elephant in the room

(2016) Daniela Giustarini et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Tumor Necrosis Factor-α Accelerates the Resolution of Established Pulmonary Fibrosis in Mice by Targeting Profibrotic Lung Macrophages

(2014) Elizabeth F. Redente et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IL-37 inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells of patients with systemic lupus erythematosus: its correlation with disease activity

(2014) Liang Ye et al.   Journal of Translational Medicine

Overexpression of Tumor Necrosis Factor-α in the Lungs Alters Immune Response, Matrix Remodeling, and Repair and Maintenance Pathways

(2012) Errol M. Thomson et al.   AMERICAN JOURNAL OF PATHOLOGY

Bleomycin revisited: towards a more representative model of IPF?

(2010) Chris J. Scotton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TGF-  regulates T-cell neurokinin-1 receptor internalization and function

(2010) M. Beinborn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNF-α induces TGF-β1expression in lung fibroblasts at the transcriptional levelviaAP-1 activation

(2009) Deborah E. Sullivan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE