Aprepitant: an antiemetic drug, contributes to the prevention of acute lung injury with its anti-inflammatory and antioxidant properties

Protective Effects of Idebenone against Sepsis Induced Acute Lung Damage

(2021) Erol Akpinar et al.   JOURNAL OF INVESTIGATIVE SURGERY

Protective effect of febuxostat in sepsis-induced liver and kidney injuries after cecal ligation and puncture with the impact of xanthine oxidase, interleukin 1β, and c-Jun N-terminal kinases

(2020) YF Ibrahim et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

The expression of thioredoxin-1 and inflammatory cytokines in patients with sepsis

(2020) Ruifei Shao et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

The NK-1R Antagonist Aprepitant Prevents LPS-Induced Oxidative Stress and Inflammation in RAW264.7 Macrophages

(2020) Xiao-nan Zhao et al.   Drug Design Development and Therapy

Effects of umbelliferone isolated from the Ferulago pauciradiata Boiss. & Heldr. Plant on cecal ligation and puncture-induced sepsis model in rats

(2020) Z. Kutlu et al.   BIOMEDICINE & PHARMACOTHERAPY

A novel effect of Aprepitant: Protection for cisplatin-induced nephrotoxicity and hepatotoxicity

(2020) Harun Un et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Can aprepitant used for nausea and vomiting be good gastrointestinal complaints?

(2020) Rustem Anil Ugan et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Ameliorative effect of gossypin against acute lung injury in experimental sepsis model of rats

(2019) Irfan Cinar et al.   LIFE SCIENCES

Antagonism of NK-1R using aprepitant suppresses inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes

(2019) Xiaoping Liu et al.   Artificial Cells Nanomedicine and Biotechnology

The role of urotensin-II and its receptors in sepsis-induced lung injury under diabetic conditions

(2018) Rustem Anil Ugan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Evaluation of oxidative stress and antioxidant status: Correlation with the severity of sepsis

(2018) S. Kumar et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Neurokinin-1 Receptor Deficiency Improves Survival in Murine Polymicrobial Sepsis Through Multiple Mechanisms in Aged Mice

(2018) Juan R. Mella et al.   SHOCK

Urotensin receptors as a new target for CLP induced septic lung injury in mice

(2018) Elif Cadirci et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Nephroprotective potential of carnitine against glycerol and contrast-induced kidney injury in rats through modulation of oxidative stress, proinflammatory cytokines, and apoptosis

(2016) Celalettin S Kunak et al.   BRITISH JOURNAL OF RADIOLOGY

Immunomodulatory and Antimicrobial Activity of Babassu Mesocarp Improves the Survival in Lethal Sepsis

(2016) Elizabeth S. B. Barroqueiro et al.   Evidence-based Complementary and Alternative Medicine

Tnf-α inhibition by infliximab as a new target for the prevention of glycerol-contrast-induced nephropathy

(2015) Murat Saritemur et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Protective effect of Et-1 receptor antagonist bosentan on paracetamol induced acute liver toxicity in rats

(2014) Muhammed Yayla et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Renoprotective effect of aliskiren on renal ischemia/reperfusion injury in rats: electron microscopy and molecular study

(2014) Tevfik Ziypak et al.   RENAL FAILURE

Effect of Monotherapy and Combination Therapy of Pantoprazole and Aprepitant in Gastric Esophageal Reflux Disease in Albino Rats

(2014) Kamleshwar Shukla et al.   TheScientificWorldJOURNAL

Peripheral 5-HT7 receptors as a new target for prevention of lung injury and mortality in septic rats

(2013) Elif Cadirci et al.   IMMUNOBIOLOGY

Protective effects of lithium: A new look at an old drug with potential antioxidative and anti-inflammatory effects in an animal model of sepsis

(2013) Abdulmecit Albayrak et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Salivary Antigen-5/CAP Family Members Are Cu2+-dependent Antioxidant Enzymes That Scavenge O2⨪and Inhibit Collagen-induced Platelet Aggregation and Neutrophil Oxidative Burst

(2013) Teresa C. F. Assumpção et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sildenafil treatment attenuates lung and kidney injury due to overproduction of oxidant activity in a rat model of sepsis: a biochemical and histopathological study

(2011) E. Cadirci et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Neurokinin-1 receptor antagonists: a comprehensive patent survey

(2010) Shih-Chung Huang et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

The Effects of Diabetes and/or Polymicrobial Sepsis on the Status of Antioxidant Enzymes and Pro-Inflammatory Cytokines on Heart, Liver, and Lung of Ovariectomized Rats

(2009) Ayse Albayrak et al.   JOURNAL OF SURGICAL RESEARCH

Substance P acts via the neurokinin receptor 1 to elicit bronchoconstriction, oxidative stress, and upregulated ICAM-1 expression after oil smoke exposure

(2008) Ping-Chia Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Activation of Neurokinin-1 Receptors during Ozone Inhalation Contributes to Epithelial Injury and Repair

(2008) Karen L. Oslund et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Regional heterogeneity of substance P-induced endothelium-dependent contraction, relaxation, and -independent contraction in rabbit pulmonary arteries

(2008) Tomohiro Miike et al.   LIFE SCIENCES