IL-37 Attenuates Lung Fibrosis by Inducing Autophagy and Regulating TGF-β1 Production in Mice

Suppression of innate inflammation and immunity by interleukin-37

(2016) Charles A. Dinarello et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interactions between Autophagy and Inhibitory Cytokines

(2016) Tian-tian Wu et al.   International Journal of Biological Sciences

Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF

(2016) Paul F Mercer et al.   THORAX

IL-37b gene transfer enhances the therapeutic efficacy of mesenchumal stromal cells in DSS-induced colitis mice

(2015) Wei-qiang Wang et al.   ACTA PHARMACOLOGICA SINICA

IL-37 requires IL-18Rα and SIGIRR/IL-1R8 to diminish allergic airway inflammation in mice

(2015) L. Lunding et al.   ALLERGY

IL-37 Alleviates Rheumatoid Arthritis by Suppressing IL-17 and IL-17–Triggering Cytokine Production and Limiting Th17 Cell Proliferation

(2015) Liang Ye et al.   JOURNAL OF IMMUNOLOGY

Regulation of TGF-β receptor hetero-oligomerization and signaling by endoglin

(2015) Leslie Pomeraniec et al.   MOLECULAR BIOLOGY OF THE CELL

IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction

(2015) Claudia A Nold-Petry et al.   NATURE IMMUNOLOGY

Immunobiology of IL-37: mechanism of action and clinical perspectives

(2014) Shannon Quirk et al.   Expert Review of Clinical Immunology

Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling

(2014) Xiwu Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

The IL-1 Family Member 7b Translocates to the Nucleus and Down-Regulates Proinflammatory Cytokines

(2014) S. Sharma et al.   JOURNAL OF IMMUNOLOGY

IL-37 Ameliorates the Inflammatory Process in Psoriasis by Suppressing Proinflammatory Cytokine Production

(2014) X. Teng et al.   JOURNAL OF IMMUNOLOGY

Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells

(2014) Yuchun Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenesis of Idiopathic Pulmonary Fibrosis

(2013) Paul J. Wolters et al.   Annual Review of Pathology-Mechanisms of Disease

Age-related disruption of autophagy in dermal fibroblasts modulates extracellular matrix components

(2013) Kanae Tashiro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transforming growth factor-β signalling: Role and consequences of Smad linker region phosphorylation

(2013) Danielle Kamato et al.   CELLULAR SIGNALLING

Overexpression of Apolipoprotein A1 in the Lung Abrogates Fibrosis in Experimental Silicosis

(2013) Eun hee Lee et al.   PLoS One

Insufficient autophagy in idiopathic pulmonary fibrosis

(2012) Jun Araya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Autophagy in Idiopathic Pulmonary Fibrosis

(2012) Avignat S. Patel et al.   PLoS One

H-Ras isoform modulates extracellular matrix synthesis, proliferation, and migration in fibroblasts

(2011) Isabel Fuentes-Calvo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

(2011) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MEK-ERK Pathway Modulation Ameliorates Pulmonary Fibrosis Associated with Epidermal Growth Factor Receptor Activation

(2011) Satish K. Madala et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Non-Smad signaling pathways

(2011) Yabing Mu et al.   CELL AND TISSUE RESEARCH

Autophagy and cytokines

(2011) James Harris   CYTOKINE

Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF- 1-Dependent and -Independent Mechanisms

(2011) S. Mi et al.   JOURNAL OF IMMUNOLOGY

Canonical and non-canonical autophagy: variations on a common theme of self-eating?

(2011) Patrice Codogno et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Interleukin 37 expression protects mice from colitis

(2011) E. N. McNamee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Expression of Interleukin-37 Reduces Local and Systemic Inflammation in Concanavalin A-Induced Hepatitis

(2011) Ana-Maria Bulau et al.   TheScientificWorldJOURNAL

Role of Lung Apolipoprotein A-I in Idiopathic Pulmonary Fibrosis

(2010) Tae Hoon Kim et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

IL-37 is a fundamental inhibitor of innate immunity

(2010) Marcel F Nold et al.   NATURE IMMUNOLOGY

TGF-β receptor levels regulate the specificity of signaling pathway activation and biological effects of TGF-β

(2009) Andres Rojas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Standardized quantification of pulmonary fibrosis in histological samples

(2008) Ralf-Harto Hübner et al.   BIOTECHNIQUES

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism