Longitudinal assessment of bleomycin-induced lung fibrosis by Micro-CT correlates with histological evaluation in mice

Heterologous Matrix Metalloproteinase Gene Promoter Activity Allows In Vivo Real-time Imaging of Bleomycin-Induced Lung Fibrosis in Transiently Transgenized Mice

(2017) Fabio Franco Stellari et al.   Frontiers in Immunology

Assessment of asthmatic inflammation using hybrid fluorescence molecular tomography–x-ray computed tomography

(2016) Xiaopeng Ma et al.   JOURNAL OF BIOMEDICAL OPTICS

Idiopathic Pulmonary Fibrosis

(2016) Maria D. Martin et al.   JOURNAL OF THORACIC IMAGING

Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory changes in lung volume

(2015) Greetje Vande Velde et al.   Disease Models & Mechanisms

The Effects of Extrafine Beclometasone/Formoterol (BDP/F) on Lung Function, Dyspnea, Hyperinflation, and Airway Geometry in COPD Patients: Novel Insight Using Functional Respiratory Imaging

(2015) Jan De Backer et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Monitoring inflammation and airway remodeling by fluorescence molecular tomography in a chronic asthma model

(2015) Fabio Stellari et al.   Journal of Translational Medicine

In vivo imaging of the lung inflammatory response to Pseudomonas aeruginosa and its modulation by azithromycin

(2015) Fabio Stellari et al.   Journal of Translational Medicine

Structural and functional correlations in a large animal model of bleomycin-induced pulmonary fibrosis

(2015) Louise Organ et al.   BMC Pulmonary Medicine

Azithromycin analogue CSY0073 attenuates lung inflammation induced by LPS challenge

(2014) V Balloy et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

(2014) David Cook et al.   NATURE REVIEWS DRUG DISCOVERY

Ultrashort-TE MRI longitudinal study and characterization of a chronic model of asthma in mice: inflammation and bronchial remodeling assessment

(2013) Andrea Bianchi et al.   NMR IN BIOMEDICINE

Bleomycin Induces Molecular Changes Directly Relevant to Idiopathic Pulmonary Fibrosis: A Model for “Active” Disease

(2013) Ruoqi Peng et al.   PLoS One

Novel Functional Imaging of Changes in Small Airways of Patients Treated with Extrafine Beclomethasone/Formoterol

(2013) Wim Vos et al.   RESPIRATION

Functional Respiratory Imaging as a Tool to Personalize Respiratory Treatment in Patients With Unilateral Diaphragmatic Paralysis

(2013) C. S. Van Holsbeke et al.   Respiratory Care

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Quantification of Lung Fibrosis and Emphysema in Mice Using Automated Micro-Computed Tomography

(2012) Ellen De Langhe et al.   PLoS One

In Vivo Micro-CT Assessment of Airway Remodeling in a Flexible OVA-Sensitized Murine Model of Asthma

(2012) Mathieu Lederlin et al.   PLoS One

Altered lung function relates to inflammation in an acute LPS mouse model

(2012) Hanna Falk Håkansson et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Effectiveness of rosiglitazone on bleomycin-induced lung fibrosis: Assessed by micro-computed tomography and pathologic scores

(2011) Gong Yong Jin et al.   EUROPEAN JOURNAL OF RADIOLOGY

Integrating mechanisms of pulmonary fibrosis

(2011) Thomas A. Wynn   JOURNAL OF EXPERIMENTAL MEDICINE

Idiopathic pulmonary fibrosis

(2011) Talmadge E King et al.   LANCET

The productivity crisis in pharmaceutical R&D

(2011) Fabio Pammolli et al.   NATURE REVIEWS DRUG DISCOVERY

Bleomycin revisited: towards a more representative model of IPF?

(2010) Chris J. Scotton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

How to improve R&D productivity: the pharmaceutical industry's grand challenge

(2010) Steven M. Paul et al.   NATURE REVIEWS DRUG DISCOVERY

Study of the Variability in Upper and Lower Airway Morphology in Sprague-Dawley Rats Using Modern Micro-CT Scan-Based Segmentation Techniques

(2009) Jan W. De Backer et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Semiquantitative Measurement of Murine Bleomycin-Induced Lung Fibrosis in In Vivo and Postmortem Conditions Using Microcomputed Tomography: Correlation With Pathologic Scores???Initial Results

(2008) Hyun Ju Lee et al.   INVESTIGATIVE RADIOLOGY

Comparison between conventional and "clinical" assessment of experimental lung fibrosis

(2008) Kjetil Ask et al.   Journal of Translational Medicine

Murine models of pulmonary fibrosis

(2007) Bethany B. Moore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY