Synthesis, characterization, evaluation of metabolic enzyme inhibitors and in silico studies of thymol based 2-amino thiol and sulfonic acid compounds

Inhibition effects of some pesticides and heavy metals on carbonic anhydrase enzyme activity purified from horse mackerel (Trachurus trachurus) gill tissues

(2020) Cuneyt Caglayan et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

A Novel Ag-N-heterocyclic Carbene Complex Bearing the Hydroxyethyl Ligand: Synthesis, Characterization, Crystal and Spectral Structures and Bioactivity Properties

(2020) Aydin Aktas et al.   Crystals

Cholinesterases, α-glycosidase, and carbonic anhydrase inhibition properties of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives: Synthetic analogues for the treatment of Alzheimer's disease and diabetes mellitus

(2020) Parham Taslimi et al.   BIOORGANIC CHEMISTRY

Novel amine-functionalized benzimidazolium salts: Synthesis, characterization, bioactivity, and molecular docking studies

(2020) Murat Yiğit et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis of novel organohalogen chalcone derivatives and screening of their molecular docking study and some enzymes inhibition effects

(2020) Serdar Burmaoglu et al.   JOURNAL OF MOLECULAR STRUCTURE

Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II As Potential Lead Enzyme Inhibitors

(2020) Cem Yamali et al.   Letters in Drug Design & Discovery

Synthesis and antioxidant activities of phenol derivatives from 1,6-bis(dimethoxyphenyl)hexane-1,6-dione

(2020) Tekin Artunc et al.   BIOORGANIC CHEMISTRY

Novel propanolamine derivatives attached to 2-metoxifenol moiety: Synthesis, characterization, biological properties, and molecular docking studies

(2020) Hayriye Genc Bilgicli et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs

(2020) Nebih Lolak et al.   BIOORGANIC CHEMISTRY

Novel functionally substituted esters based on sodium diethyldithiocarbamate derivatives: Synthesis, characterization, biological activity and molecular docking studies

(2020) Alverdi Karimov et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization, photo-physicochemical and biological properties of water-soluble tetra-substituted phthalocyanines: Antidiabetic, anticancer and anticholinergic potentials

(2020) Armağan Günsel et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

Intracellular Binding/Unbinding Kinetics of Approved Drugs to Carbonic Anhydrase II Observed by in-Cell NMR

(2020) Enrico Luchinat et al.   ACS Chemical Biology

The Effect of Nanoparticles on the Structure and Enzymatic Activity of Human Carbonic Anhydrase I and II

(2020) Celia Cabaleiro-Lago et al.   MOLECULES

Analogues of 2′-hydroxychalcone with modified C4-substituents as the inhibitors against human acetylcholinesterase

(2020) Sri Devi Sukumaran et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis, characterization and bioactivities of dative donor ligand N-heterocyclic carbene (NHC) precursors and their Ag(I)NHC coordination compounds

(2020) Ali Kazancı et al.   POLYHEDRON

Synthesis of Oxazolidinone from Enantiomerically Enriched Allylic Alcohols and Determination of Their Molecular Docking and Biologic Activities

(2019) Ufuk Atmaca et al.   BIOORGANIC CHEMISTRY

Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors

(2019) Fikret Turkan et al.   BIOORGANIC CHEMISTRY

Synthesis and biological evaluation of bromophenol derivatives with cyclopropyl moiety: Ring opening of cyclopropane with monoester

(2019) Murat Boztas et al.   BIOORGANIC CHEMISTRY

Preliminary phytochemical analysis and evaluation of in vitro antioxidant, antiproliferative, antidiabetic, and anticholinergics effects of endemic Gypsophila taxa from Turkey

(2019) Ahmet Altay et al.   JOURNAL OF FOOD BIOCHEMISTRY

Sage (Salvia pilifera): determination of its polyphenol contents, anticholinergic, antidiabetic and antioxidant activities

(2019) İlhami Gülçin et al.   Journal of Food Measurement and Characterization

Synthesis and characterization of novel bromophenols: Determination of their anticholinergic, antidiabetic and antioxidant activities

(2019) Necla Öztaşkın et al.   BIOORGANIC CHEMISTRY

Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors

(2019) Mehtap Tugrak et al.   BIOORGANIC CHEMISTRY

The green synthesis and molecular docking of novel N-substituted rhodanines as effective inhibitors for carbonic anhydrase and acetylcholinesterase enzymes

(2019) Sinan Bayindir et al.   BIOORGANIC CHEMISTRY

Novel 2-methylimidazolium salts: Synthesis, characterization, molecular docking, and carbonic anhydrase and acetylcholinesterase inhibitory properties

(2019) Selma Bal et al.   BIOORGANIC CHEMISTRY

Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties

(2019) Fatoş Erdemir et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization and biological evaluation of N ‐substituted triazinane‐2‐thiones and theoretical–experimental mechanism of condensation reaction

(2019) Afsun Sujayev et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Novel tribenzylaminobenzolsulphonylimine based on their pyrazine and pyridazines: Synthesis, characterization, antidiabetic, anticancer, anticholinergic, and molecular docking studies

(2019) Gulnar Mamedova et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization and crystal structure of 2-(4-hydroxyphenyl)ethyl and 2-(4-nitrophenyl)ethyl Substituted Benzimidazole Bromide Salts: Their inhibitory properties against carbonic anhydrase and acetylcholinesterase

(2018) Ayten Behçet et al.   JOURNAL OF MOLECULAR STRUCTURE

Novel Benzylic Substituted Imidazolinium, Tetrahydropyrimidinium and Tetrahydrodiazepinium Salts: Potent Carbonic Anhydrase and Acetylcholinesterase Inhibitors

(2018) Beyhan Yiğit et al.   ChemistrySelect

Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors – Their antidiabetic, anticholinergic and antibacterial potentials

(2018) Mustafa Zengin et al.   BIOORGANIC CHEMISTRY

Diarylmethanon, bromophenol and diarylmethane compounds: Discovery of potent aldose reductase, α-amylase and α-glycosidase inhibitors as new therapeutic approach in diabetes and functional hyperglycemia

(2018) Parham Taslimi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synthesis, characterization, crystal structure, electrochemical studies and biological evaluation of metal complexes with thiosemicarbazone of glyoxylic acid

(2018) Mansura Huseynova et al.   POLYHEDRON

Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract

(2018) N. Eruygur et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Identification of novel acetylcholinesterase inhibitors designed by pharmacophore-based virtual screening, molecular docking and bioassay

(2018) Cheongyun Jang et al.   Scientific Reports

Novel morpholine liganded Pd-based N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure, antidiabetic and anticholinergic properties

(2018) Aydın Aktaş et al.   POLYHEDRON

Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity

(2018) Dilan Ozmen Ozgun et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization, crystal structure of novel bis-thiomethylcyclohexanone derivatives and their inhibitory properties against some metabolic enzymes

(2018) Abdullah Biçer et al.   BIOORGANIC CHEMISTRY

Recent progress in the identification of selective butyrylcholinesterase inhibitors for Alzheimer's disease

(2017) Qi Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The Idiopathic Intracranial Hypertension Treatment Trial: A Review of the Outcomes

(2017) Stacy V. Smith et al.   HEADACHE

Secondary Sulfonamides as Effective Lactoperoxidase Inhibitors

(2017) Zeynep Köksal et al.   MOLECULES

Antibacterial and antifungal activities of thymol: A brief review of the literature

(2016) Anna Marchese et al.   FOOD CHEMISTRY

Ribosomal Synthesis of Macrocyclic Peptides in Vitro and in Vivo Mediated by Genetically Encoded Aminothiol Unnatural Amino Acids

(2015) John R. Frost et al.   ACS Chemical Biology

Sulfonamides and their isosters as carbonic anhydrase inhibitors

(2014) Fabrizio Carta et al.   Future Medicinal Chemistry

A review on cholinesterase inhibitors for Alzheimer’s disease

(2013) Preet Anand et al.   ARCHIVES OF PHARMACAL RESEARCH

Synthetic Methodologies for the Preparation of β-Amino Thiols

(2012) Guillaume Mercey et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Versatile synthesis of α-substituted taurines from nitroolefins

(2010) Chuanxiang Xu et al.   AMINO ACIDS

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY

Bromoethylsulfonium SaltA More Effective Annulation Agent for the Synthesis of 6- and 7-Membered 1,4-Heterocyclic Compounds

(2008) Muhammad Yar et al.   ORGANIC LETTERS

Efficient synthesis of primary 2-aminothiols from 2-aminoalcohols and methyldithioacetate

(2008) Guillaume Mercey et al.   TETRAHEDRON LETTERS