Journal
ORGANIC LETTERS
Volume 11, Issue 2, Pages 257-260Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol8023727
Keywords
-
Categories
Funding
- Higher Education Commission of Pakistan
- Royal Society for a Wolfson Research
- EPSRC
Ask authors/readers for more resources
Reaction of bromoethylsulfonium salt with 1,2-/1,3-aminoalcohols gave six- and seven-membered rings in good-to-excel lent yields. The reactions proceed through generation of a vinyl sulfonium salt followed by annulation to give 1,4-heterocyclic compounds such as morpholines and benzoxazepines in a simple procedure. The method accommodates a range of nitrogen substituents and the amino alcohol can be substituted by amino thiols and diamines to give thiomorpholines, piperazines and benzodiazepines.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available