Cellular mechanisms of oligoclonal vascular smooth muscle cell expansion in cardiovascular disease

Mechanisms of vascular smooth muscle cell investment and phenotypic diversification in vascular diseases

(2021) Matthew D. Worssam et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

TET2 Protects Against Vascular Smooth Muscle Cell Apoptosis and Intimal Thickening in Transplant Vasculopathy

(2021) Allison C. Ostriker et al.   CIRCULATION

Antagonistic relationship between the unfolded protein response and myocardin‐driven transcription in smooth muscle

(2020) Baoyi Zhu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Smooth Muscle Cell Reprogramming in Aortic Aneurysms

(2020) Pei-Yu Chen et al.   Cell Stem Cell

Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm

(2020) Albert J. Pedroza et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis

(2020) Gabriel F. Alencar et al.   CIRCULATION

Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade

(2020) Ying Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human

(2020) Huize Pan et al.   CIRCULATION

A Notch3-Marked Subpopulation of Vascular Smooth Muscle Cells Is the Cell of Origin for Occlusive Pulmonary Vascular Lesions

(2020) Lea C. Steffes et al.   CIRCULATION

Sca1 + Cells Minimally Contribute to Smooth Muscle Cells in Atherosclerosis

(2020) Haixiao Wang et al.   CIRCULATION RESEARCH

Promoters to Study Vascular Smooth Muscle

(2019) Raja Chakraborty et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Smooth Muscle Cell Phenotypic Diversity

(2019) Mingjun Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms

(2019) Marc Clément et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The role of smooth muscle cells in plaque stability: Therapeutic targeting potential

(2019) Jennifer L. Harman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis

(2019) Robert C. Wirka et al.   NATURE MEDICINE

Vascular smooth muscle cells in atherosclerosis

(2019) Gemma L. Basatemur et al.   Nature Reviews Cardiology

Arterial Sca1+ Vascular Stem Cells Generate De Novo Smooth Muscle for Artery Repair and Regeneration

(2019) Juan Tang et al.   Cell Stem Cell

Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

(2018) Kelly Street et al.   BMC GENOMICS

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells

(2018) Ashish Misra et al.   Nature Communications

Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels

(2018) Lina Dobnikar et al.   Nature Communications

Reconciling Smooth Muscle Cell Oligoclonality and Proliferative Capacity in Experimental Atherosclerosis

(2016) Delphine Gomez et al.   CIRCULATION RESEARCH

Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis ModelsNovelty and Significance

(2016) Joel Chappell et al.   CIRCULATION RESEARCH

Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective

(2016) Olga A Cherepanova et al.   NATURE MEDICINE

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

(2015) Laura S Shankman et al.   NATURE MEDICINE

Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis

(2014) Susanne Feil et al.   CIRCULATION RESEARCH

Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele

(2014) O. Basak et al.   EMBO JOURNAL

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Detection of histone modifications at specific gene loci in single cells in histological sections

(2013) Delphine Gomez et al.   NATURE METHODS

Unravelling stem cell dynamics by lineage tracing

(2013) Cédric Blanpain et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dynamic Immune Cell Accumulation During Flow-Induced Atherogenesis in Mouse Carotid Artery

(2012) Noah Alberts-Grill et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Radial Construction of an Arterial Wall

(2012) Daniel M. Greif et al.   DEVELOPMENTAL CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Smooth Muscle Cell Apoptosis Promotes Vessel Remodeling and Repair via Activation of Cell Migration, Proliferation, and Collagen Synthesis

(2011) Haixiang Yu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

SDF-1α Induction in Mature Smooth Muscle Cells by Inactivation of PTEN Is a Critical Mediator of Exacerbated Injury-Induced Neointima Formation

(2011) Raphael A. Nemenoff et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Smooth Muscle Notch1 Mediates Neointimal Formation After Vascular Injury

(2009) Yuxin Li et al.   CIRCULATION