Early posttraumatic CSF1R inhibition via PLX3397 leads to time- and sex-dependent effects on inflammation and neuronal maintenance after traumatic brain injury in mice
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Title
Early posttraumatic CSF1R inhibition via PLX3397 leads to time- and sex-dependent effects on inflammation and neuronal maintenance after traumatic brain injury in mice
Authors
Keywords
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Journal
BRAIN BEHAVIOR AND IMMUNITY
Volume 106, Issue -, Pages 49-66
Publisher
Elsevier BV
Online
2022-08-03
DOI
10.1016/j.bbi.2022.07.164
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Note: Only part of the references are listed.- Acute minocycline administration reduces brain injury and improves long-term functional outcomes after delayed hypoxemia following traumatic brain injury
- (2022) Marta Celorrio et al. Acta Neuropathologica Communications
- Chronic Cortical Inflammation, Cognitive Impairment, and Immune Reactivity Associated with Diffuse Brain Injury Are Ameliorated by Forced Turnover of Microglia
- (2022) Chelsea E. Bray et al. JOURNAL OF NEUROSCIENCE
- Traumatic brain injury causes chronic cortical inflammation and neuronal dysfunction mediated by microglia
- (2021) Kristina G. Witcher et al. JOURNAL OF NEUROSCIENCE
- Early Reciprocal Effects in a Murine Model of Traumatic Brain Injury and Femoral Fracture
- (2021) Katharina Ritter et al. MEDIATORS OF INFLAMMATION
- Photoactivatable CaMKII induces synaptic plasticity in single synapses
- (2021) Akihiro C. E. Shibata et al. Nature Communications
- Considering Biological Sex in Traumatic Brain Injury
- (2021) Anat Biegon Frontiers in Neurology
- Single intracerebroventricular progranulin injection adversely affects the blood–brain barrier in experimental traumatic brain injury
- (2021) Regina Hummel et al. JOURNAL OF NEUROCHEMISTRY
- Uncovering sex differences of rodent microglia
- (2021) Jinming Han et al. Journal of Neuroinflammation
- Neuroimmune cleanup crews in brain injury
- (2021) Ashley C. Bolte et al. TRENDS IN IMMUNOLOGY
- Sex and age differences in isolated traumatic brain injury: a retrospective observational study
- (2021) Sanae Hosomi et al. BMC Neurology
- Pyk2 in dorsal hippocampus plays a selective role in spatial memory and synaptic plasticity
- (2021) Vincenzo Mastrolia et al. Scientific Reports
- Inflammatory Regulation of CNS Barriers After Traumatic Brain Injury: A Tale Directed by Interleukin-1
- (2021) Colleen N. Bodnar et al. Frontiers in Immunology
- Microglial depletion with CSF1R inhibitor during chronic phase of experimental traumatic brain injury reduces neurodegeneration and neurological deficits
- (2020) Rebecca J. Henry et al. JOURNAL OF NEUROSCIENCE
- Cell Death and Recovery in Traumatic Brain Injury
- (2020) Yosuke Akamatsu et al. Neurotherapeutics
- Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner
- (2020) Emily F. Willis et al. CELL
- To Kill a Microglia: A Case for CSF1R Inhibitors
- (2020) Kim N. Green et al. TRENDS IN IMMUNOLOGY
- Administration of all‐ trans retinoic acid after experimental traumatic brain injury is brain protective
- (2020) Regina Hummel et al. BRITISH JOURNAL OF PHARMACOLOGY
- Proton extrusion during oxidative burst in microglia exacerbates pathological acidosis following traumatic brain injury
- (2020) Rodney M. Ritzel et al. GLIA
- Attenuated CSF‐1R signalling drives cerebrovascular pathology
- (2020) Conor Delaney et al. EMBO Molecular Medicine
- Rapid clearance of cellular debris by microglia limits secondary neuronal cell death after brain injury in vivo
- (2019) Chiara Herzog et al. DEVELOPMENT
- Depletion of microglia immediately following traumatic brain injury in the pediatric rat: Implications for cellular and behavioral pathology
- (2019) Lauren A. Hanlon et al. EXPERIMENTAL NEUROLOGY
- Depletion of Microglia Attenuates Dendritic Spine Loss and Neuronal Apoptosis in the Acute Stage of Moderate Traumatic Brain Injury in Mice
- (2019) Chuan-fang Wang et al. JOURNAL OF NEUROTRAUMA
- CSF1R Ligands IL-34 and CSF1 Are Differentially Required for Microglia Development and Maintenance in White and Gray Matter Brain Regions
- (2019) Courtney Easley-Neal et al. Frontiers in Immunology
- A Mouse Model for Juvenile, Lateral Fluid Percussion Brain Injury Reveals Sex-Dependent Differences in Neuroinflammation and Functional Recovery
- (2019) Elizabeth A. Newell et al. JOURNAL OF NEUROTRAUMA
- Dual microglia effects on blood brain barrier permeability induced by systemic inflammation
- (2019) Koichiro Haruwaka et al. Nature Communications
- Sex-related responses after traumatic brain injury: Considerations for preclinical modeling
- (2018) Claudia B. Späni et al. FRONTIERS IN NEUROENDOCRINOLOGY
- NG2/CSPG4 and progranulin in the posttraumatic glial scar
- (2018) Michael K.E. Schäfer et al. MATRIX BIOLOGY
- The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms
- (2018) Salvatore Incontro et al. Nature Communications
- NGL-2 Deletion Leads to Autistic-like Behaviors Responsive to NMDAR Modulation
- (2018) Seung Min Um et al. Cell Reports
- The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments
- (2018) Maria Cristina Morganti-Kossmann et al. ACTA NEUROPATHOLOGICA
- Traumatic brain injury-induced neuronal damage in the somatosensory cortex causes formation of rod-shaped microglia that promote astrogliosis and persistent neuroinflammation
- (2018) Kristina G. Witcher et al. GLIA
- Enforced microglial depletion and repopulation as a promising strategy for the treatment of neurological disorders
- (2018) Jinming Han et al. GLIA
- Chronic Upregulation of Cleaved-Caspase-3 Associated with Chronic Myelin Pathology and Microvascular Reorganization in the Thalamus after Traumatic Brain Injury in Rats
- (2018) Andriy Glushakov et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Alzheimer's Disease Risk Factor Pyk2 Mediates Amyloid-β Induced Synaptic Dysfunction and Loss
- (2018) Santiago V. Salazar et al. JOURNAL OF NEUROSCIENCE
- Sexual dimorphism in the inflammatory response to traumatic brain injury
- (2017) Sonia Villapol et al. GLIA
- Microglia Are Irrelevant for Neuronal Degeneration and Axon Regeneration after Acute Injury
- (2017) Alexander M. Hilla et al. JOURNAL OF NEUROSCIENCE
- Modulators of microglial activation and polarization after intracerebral haemorrhage
- (2017) Xi Lan et al. Nature Reviews Neurology
- The far-reaching scope of neuroinflammation after traumatic brain injury
- (2017) Dennis W. Simon et al. Nature Reviews Neurology
- Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift
- (2017) Yasir N. Jassam et al. NEURON
- Microglial Activation in Traumatic Brain Injury
- (2017) Cornelius K. Donat et al. Frontiers in Aging Neuroscience
- Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation
- (2016) Hansen Lui et al. CELL
- Microglia in the TBI brain: The good, the bad, and the dysregulated
- (2016) David J. Loane et al. EXPERIMENTAL NEUROLOGY
- Do microglia play a role in sex differences in TBI?
- (2016) Henry W. Caplan et al. JOURNAL OF NEUROSCIENCE RESEARCH
- A polarizing question: do M1 and M2 microglia exist?
- (2016) Richard M Ransohoff NATURE NEUROSCIENCE
- Changes in Binding of [123I]CLINDE, a High-Affinity Translocator Protein 18 kDa (TSPO) Selective Radioligand in a Rat Model of Traumatic Brain Injury
- (2016) Cornelius K. Donat et al. NEUROMOLECULAR MEDICINE
- The contribution of astrocytes and microglia to traumatic brain injury
- (2015) Ila P Karve et al. BRITISH JOURNAL OF PHARMACOLOGY
- Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus
- (2015) R. A. Rice et al. JOURNAL OF NEUROSCIENCE
- Homeostasis of Microglia in the Adult Brain: Review of Novel Microglia Depletion Systems
- (2015) Ari Waisman et al. TRENDS IN IMMUNOLOGY
- Perivascular microglia promote blood vessel disintegration in the ischemic penumbra
- (2014) Valérie Jolivel et al. ACTA NEUROPATHOLOGICA
- Regulators of mitochondrial Ca2+ homeostasis in cerebral ischemia
- (2014) Michael K. E. Schäfer et al. CELL AND TISSUE RESEARCH
- CSF1 overexpression has pleiotropic effects on microgliain vivo
- (2014) Ishani De et al. GLIA
- Interactions of Oxidative Stress and Neurovascular Inflammation in the Pathogenesis of Traumatic Brain Injury
- (2014) P. M. Abdul-Muneer et al. MOLECULAR NEUROBIOLOGY
- Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
- (2014) Monica R.P. Elmore et al. NEURON
- IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase
- (2013) Ling Ye et al. JOURNAL OF NEUROCHEMISTRY
- Phagocytosis executes delayed neuronal death after focal brain ischemia
- (2013) J. J. Neher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neural circuit mechanisms of post–traumatic epilepsy
- (2013) Robert F. Hunt et al. Frontiers in Cellular Neuroscience
- Microglia-derived TNFα induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma
- (2013) J Guadagno et al. Cell Death & Disease
- A Review of Neuroprotection Pharmacology and Therapies in Patients with Acute Traumatic Brain Injury
- (2012) Kevin W. McConeghy et al. CNS DRUGS
- Candesartan, an Angiotensin II AT1-Receptor Blocker and PPAR-γ Agonist, Reduces Lesion Volume and Improves Motor and Memory Function After Traumatic Brain Injury in Mice
- (2012) Sonia Villapol et al. NEUROPSYCHOPHARMACOLOGY
- Inflammation after trauma: Microglial activation and traumatic brain injury
- (2011) Anil F. Ramlackhansingh et al. ANNALS OF NEUROLOGY
- GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
- (2009) Eran Eden et al. BMC BIOINFORMATICS
- Neutralization of interleukin-1β modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice
- (2009) Fredrik Clausen et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals
- (2009) H. Wake et al. JOURNAL OF NEUROSCIENCE
- Recovery of Afferent Function and Synaptic Strength in Hippocampal CA1 following Traumatic Brain Injury
- (2009) Christopher M. Norris et al. JOURNAL OF NEUROTRAUMA
- Debris clearance by microglia: an essential link between degeneration and regeneration
- (2008) H. Neumann et al. BRAIN
- Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury
- (2008) Mubeen A. Ansari et al. FREE RADICAL BIOLOGY AND MEDICINE
- Selection of Endogenous Control Genes for Normalization of Gene Expression Analysis after Experimental Brain Trauma in Mice
- (2008) Serge C. Thal et al. JOURNAL OF NEUROTRAUMA
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