Candesartan, an Angiotensin II AT1-Receptor Blocker and PPAR-γ Agonist, Reduces Lesion Volume and Improves Motor and Memory Function After Traumatic Brain Injury in Mice
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Candesartan, an Angiotensin II AT1-Receptor Blocker and PPAR-γ Agonist, Reduces Lesion Volume and Improves Motor and Memory Function After Traumatic Brain Injury in Mice
Authors
Keywords
-
Journal
NEUROPSYCHOPHARMACOLOGY
Volume 37, Issue 13, Pages 2817-2829
Publisher
Springer Nature
Online
2012-08-15
DOI
10.1038/npp.2012.152
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- ARE ACE-INHIBITORS OR ARB’S STILL NEEDED FOR CARDIOVASCULAR PREVENTION IN HIGH RISK PATIENTS? INSIGHTS FROM PROFESS AND TRANSCEND
- (2014) W. Van Mieghem et al. ACTA CLINICA BELGICA
- Renin-angiotensin System Blockers and Modulation of Radiation-Induced Brain Injury
- (2012) M. E. Robbins et al. CURRENT DRUG TARGETS
- Delayed inhibition of angiotensin II receptor type 1 reduces secondary brain damage and improves functional recovery after experimental brain trauma*
- (2011) Ralph Timaru-Kast et al. CRITICAL CARE MEDICINE
- Telmisartan ameliorates lipopolysaccharide-induced innate immune response through peroxisome proliferator-activated receptor-γ activation in human monocytes
- (2011) Tao Pang et al. JOURNAL OF HYPERTENSION
- Smad proteins differentially regulate transforming growth factor-β-mediated induction of chondroitin sulfate proteoglycans
- (2011) Bala T. S. Susarla et al. JOURNAL OF NEUROCHEMISTRY
- Activation of cerebral peroxisome proliferator-activated receptors γ (PPARγ) reduces neuronal damage in the substantia nigra after transient focal cerebral ischaemia in the rat
- (2011) M. Zuhayra et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Animal models of traumatic brain injury: A critical evaluation
- (2011) William T. O'Connor et al. PHARMACOLOGY & THERAPEUTICS
- Valsartan attenuated oxidative stress, decreased MCP-1 and TGF-β1 expression in glomerular mesangial and epithelial cells induced by high-glucose levels
- (2011) Bo Jiao et al. BioScience Trends
- Acute Treatment with Candesartan Reduces Early Injury After Permanent Middle Cerebral Artery Occlusion
- (2011) Weihua Guan et al. Translational Stroke Research
- The Association between Hypertension and Dementia in the Elderly
- (2011) Michiya Igase et al. International Journal of Hypertension
- Telmisartan suppresses cerebral injury in a murine model of transient focal ischemia
- (2010) Yukiko Kasahara et al. BRAIN RESEARCH
- Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here?
- (2010) Niklas Marklund et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Molecular Pathophysiology of Concussive Brain Injury
- (2010) Garni Barkhoudarian et al. CLINICS IN SPORTS MEDICINE
- Angiotensin II revisited: new roles in inflammation, immunology and aging
- (2010) Ariela Benigni et al. EMBO Molecular Medicine
- Losartan inhibits LPS-induced inflammatory signaling through a PPARγ-dependent mechanism in human THP-1 macrophages
- (2010) Jianbo An et al. HYPERTENSION RESEARCH
- Angiotensin II sustains brain inflammation in mice via TGF-β
- (2010) Tobias V. Lanz et al. JOURNAL OF CLINICAL INVESTIGATION
- Amlodipine suppressed cardiac gene expression of brain natriuretic peptide, transforming growth factor-β1and fibronectin mediated by aldosterone in male stroke-prone spontaneously hypertensive rats
- (2010) Shinsuke Harasawa et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Effect of Combined Treatment With Curcumin and Candesartan on Ischemic Brain Damage in Mice
- (2010) Azza S. Awad Journal of Stroke & Cerebrovascular Diseases
- Vasopressor Use and Effect on Blood Pressure After Severe Adult Traumatic Brain Injury
- (2010) Pimwan Sookplung et al. Neurocritical Care
- Angiotensin II AT1 Receptor Blockade Ameliorates Brain Inflammation
- (2010) Julius Benicky et al. NEUROPSYCHOPHARMACOLOGY
- Melatonin Promotes Myelination by Decreasing White Matter Inflammation After Neonatal Stroke
- (2010) Sonia Villapol et al. PEDIATRIC RESEARCH
- PPAR Modulation of Kinase-Linked Receptor Signaling in Physiology and Disease
- (2010) Nicolas Rotman et al. PHYSIOLOGY
- Blockade of brain angiotensin II AT1 receptors ameliorates stress, anxiety, brain inflammation and ischemia: Therapeutic implications
- (2010) Juan M. Saavedra et al. PSYCHONEUROENDOCRINOLOGY
- Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies
- (2010) David J. Loane et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Crosstalk between peroxisome proliferator-activated receptor-γ and angiotensin II in renal tubular epithelial cells in IgA nephropathy
- (2009) Jing Xiao et al. CLINICAL IMMUNOLOGY
- Postischemic administration of angiotensin II type 1 receptor blocker reduces cerebral infarction size in hypertensive rats
- (2009) Emi Omura-Matsuoka et al. HYPERTENSION RESEARCH
- Immunosuppressive effect of angiotensin receptor blocker on stimulation of mice CTLs by angiotensin II
- (2009) Akihiko Maeda et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Candesartan reduces the innate immune response to lipopolysaccharide in human monocytes
- (2009) Ignacio M Larrayoz et al. JOURNAL OF HYPERTENSION
- PPARγ agonist, rosiglitazone, regulates angiotensin II-induced vascular inflammation through the TLR4-dependent signaling pathway
- (2009) Yuanyuan Ji et al. LABORATORY INVESTIGATION
- PPARγ agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms
- (2008) Jae-Hyuk Yi et al. BRAIN RESEARCH
- Prevention and reduction of scarring in the skin by Transforming Growth Factor beta 3 (TGFβ3): from laboratory discovery to clinical pharmaceutical
- (2008) Nick L. Occleston et al. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
- Protective mechanisms of the angiotensin II type 1 receptor blocker candesartan against cerebral ischemia: in-vivo and in-vitro studies
- (2008) Hao Liu et al. JOURNAL OF HYPERTENSION
- Brain angiotensin enhances dopaminergic cell death via microglial activation and NADPH-derived ROS
- (2008) J. Rodriguez-Pallares et al. NEUROBIOLOGY OF DISEASE
- Effects of Antihypertensive Drug Treatment on the Risk of Dementia and Cognitive Impairment
- (2008) Ivy O Poon PHARMACOTHERAPY
- Temporary Pretreatment With the Angiotensin II Type 1 Receptor Blocker, Valsartan, Prevents Ischemic Brain Damage Through an Increase in Capillary Density
- (2008) Jian-Mei Li et al. STROKE
- PPAR-, Microglial Cells, and Ocular Inflammation: New Venues for Potential Therapeutic Approaches
- (2008) Fiorella Malchiodi-Albedi et al. PPAR Research
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now