IL1RAP expression and the enrichment of IL ‐33 activation signatures in severe neutrophilic asthma

Neutrophilic asthma: misconception or misnomer?

(2021) Parameswaran Nair et al.   Lancet Respiratory Medicine

Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: a randomized clinical trial

(2021) Steven G. Kelsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Current and future status of JAK inhibitors

(2021) Donal P McLornan et al.   LANCET

Reframing Immune-Mediated Inflammatory Diseases through Signature Cytokine Hubs

(2021) Georg Schett et al.   NEW ENGLAND JOURNAL OF MEDICINE

The central role of IL-33/IL-1RL1 pathway in asthma: From pathogenesis to intervention

(2021) A.K. Saikumar Jayalatha et al.   PHARMACOLOGY & THERAPEUTICS

Efficacy and Safety of Itepekimab in Patients with Moderate-to-Severe Asthma

(2021) Michael E. Wechsler et al.   NEW ENGLAND JOURNAL OF MEDICINE

TSLP Inhibitors for Asthma: Current Status and Future Prospects

(2020) Maria Gabriella Matera et al.   DRUGS

Phenotypic and functional translation of IL33 genetics in asthma

(2020) Maria E. Ketelaar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL‐1 signaling pathway molecules as key markers in childhood asthma

(2020) Wenping Wei et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

IL-33 Alarmin and Its Active Proinflammatory Fragments Are Released in Small Intestine in Celiac Disease

(2020) Federico Perez et al.   Frontiers in Immunology

Innate Control of Tissue-Reparative Human Regulatory T Cells

(2019) Avery J. Lam et al.   JOURNAL OF IMMUNOLOGY

A cellular census of human lungs identifies novel cell states in health and in asthma

(2019) Felipe A. Vieira Braga et al.   NATURE MEDICINE

Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma

(2019) Leena George et al.   ALLERGY

Tezepelumab: a novel biological therapy for the treatment of severe uncontrolled asthma

(2019) Giancarlo Marone et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease

(2019) Jesper Falkesgaard Højen et al.   NATURE IMMUNOLOGY

Mast cell activation test in the diagnosis of allergic disease and anaphylaxis

(2018) Rajia Bahri et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-33 drives influenza-induced asthma exacerbations by halting innate and adaptive antiviral immunity

(2018) Lara Ravanetti et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED

(2017) Chih-Hsi Scott Kuo et al.   EUROPEAN RESPIRATORY JOURNAL

Sputum cell IL-1 receptor expression level is a marker of airway neutrophilia and airflow obstruction in asthmatic patients

(2017) Michael D. Evans et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma

(2017) Dirk Smith et al.   PLoS Genetics

The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases

(2017) Brad Griesenauer et al.   Frontiers in Immunology

Dysregulation of Vascular Endothelial Progenitor Cells Lung-Homing in Subjects with COPD

(2016) Brittany M. Salter et al.   Canadian Respiratory Journal

The challenge of measuring IL-33 in serum using commercial ELISA: lessons from asthma

(2016) M. E. Ketelaar et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Severe asthma exists despite suppressed tissue inflammation: findings of the U-BIOPRED study

(2016) Susan J. Wilson et al.   EUROPEAN RESPIRATORY JOURNAL

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Microparticles in sputum of COPD patients: a potential biomarker of the disease?

(2016) Chiara Porro et al.   International Journal of Chronic Obstructive Pulmonary Disease

T-bet– and STAT4–dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses

(2015) Claudia Baumann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation

(2015) E. Suzanne Cohen et al.   Nature Communications

Expression Profiling of Human Basophils: Modulation by Cytokines and Secretagogues

(2015) Donald MacGlashan   PLoS One

IL-33–Dependent Type 2 Inflammation during Rhinovirus-induced Asthma ExacerbationsIn Vivo

(2014) David J. Jackson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Association of IL33–IL-1 receptor–like 1 (IL1RL1) pathway polymorphisms with wheezing phenotypes and asthma in childhood

(2014) Olga E. Savenije et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-33/ST2 axis promotes mast cell survival via BCLXL

(2014) J.-X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Increased Expression of IL-33 in Severe Asthma: Evidence of Expression by Airway Smooth Muscle Cells

(2009) D. Prefontaine et al.   JOURNAL OF IMMUNOLOGY

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One