Article
Chemistry, Physical
Vidmantas Bieliunas, Sigitas Stoncius
Summary: The design and synthesis of second generation C-2-symmetric ligands with additional substituents was reported. These substituents provide a further element for fine-tuning the ligand structure by enforcing conformational rigidity. The tetrasubstituted bicyclo[3.3.1]nona-2,6-dienes were successfully employed in the rhodium-catalyzed arylation reaction with good to excellent yields and enantioselectivities up to 99% ee.
Article
Chemistry, Multidisciplinary
Enrika Celitan, Albinas Zilinskas, Jolanta Sereikaite
Summary: In this study, vegetables were screened as biocatalysts for the stereoselective biotransformation of racemic bicyclo[3.3.1]nonane-2,6-diol diacetate. Carrot, parsnip, and ginger roots and rootstocks were found to be the most effective in the enzymatic hydrolysis of the substrate. Different reaction conditions and plant materials resulted in the formation of different enantiomers.
GREEN CHEMISTRY LETTERS AND REVIEWS
(2022)
Article
Chemistry, Organic
Showkat Rashid, Bilal Bhat, Goverdhan Mehta
Summary: An efficient trimerization of ynals to form diversely substituted 4H-pyran constructs has been achieved in water under ambient conditions using micellar catalysis. The reaction site of the micelles was probed through proton NMR studies, and a downstream acid-mediated rearrangement to 2,8-dioxabicyclo[3.3.1]nona-3,6-dienes was observed.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
A. K. Fazlur Rahman, Martin A. Bennett
Summary: The activation of C-C bond in coordinated M (eta(4) bicyclo [2.2.1]-hepta-diene) or 2,5-NBD via protonation for 3d,4d and 5d transition metals has been investigated, leading to the formation of transient agostic metal hydrides and stable vinyl eta(3) cyclopentenyl cations under specific conditions. Protonation reactions with different acids resulted in variable stability of the hydride complexes and subsequent ligand migration for stable products.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
A. K. Fazlur-Rahman, Martin A. Bennett
Summary: This study presents the synthesis, protonation reactions, and skeletal rearrangements of a series of complexes. Protonation of these complexes can lead to the formation of agostic M-H-C structures. The resulting cationic salts can undergo hydride migration and carbon-carbon bond cleavage to generate various cyclohexenyl cations.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Gabriele Pupo, Anna Chiara Vicini, David M. H. Ascough, Francesco Ibba, Kirsten E. Christensen, Amber L. Thompson, John M. Brown, Robert S. Paton, Veronique Gouverneur
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2019)
Article
Multidisciplinary Sciences
Abimael Cruz-Migoni, Peter Canning, Camilo E. Quevedo, Carole J. R. Bataille, Nicolas Bery, Ami Miller, Angela J. Russell, Simon E. V. Phillips, Stephen B. Carr, Terence H. Rabbitts
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2019)
Article
Biochemistry & Molecular Biology
Daniel Lucy, Gareth S. D. Purvis, Lynda Zeboudj, Maria Chatzopoulou, Carlota Recio, Carole J. R. Bataille, Graham M. Wynne, David R. Greaves, Angela J. Russell
ACS CHEMICAL BIOLOGY
(2019)
Review
Chemistry, Organic
Frederick A. Partridge, Ruth A. Forman, Carole J. R. Bataille, Graham M. Wynne, Marina Nick, Angela J. Russell, Kathryn J. Else, David B. Sattelle
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Hematology
Peng Hua, Joanna Hester, George Adigbli, Rong Li, Bethan Psaila, Anindita Roy, Carole J. R. Bataille, Graham M. Wynne, Thomas Jackson, Thomas A. Milne, Angela J. Russell, James Davies, Irene Roberts, Fadi Issa, Suzanne M. Watt
Article
Biochemistry & Molecular Biology
Camilo E. Quevedo, Carole J. R. Bataille, Simon Byrne, Matthew Durbin, Jon Elkins, Abigail Guillermo, Alan M. Jones, Stefan Knapp, Anna Nadali, Roderick G. Walker, Isabel V. L. Wilkinson, Graham M. Wynne, Stephen G. Davies, Angela J. Russell
BIOORGANIC & MEDICINAL CHEMISTRY
(2020)
Article
Biochemistry & Molecular Biology
Vincent B. Luscombe, Daniel Lucy, Carole J. R. Bataille, Angela J. Russell, David R. Greaves
DNA AND CELL BIOLOGY
(2020)
Review
Chemistry, Applied
Christiane Schotten, Richard A. Bourne, Nikil Kapur, Bao N. Nguyen, Charlotte E. Willans
Summary: The electrochemical generation of N-heterocyclic carbenes (NHCs) provides a mild and selective alternative to traditional synthetic methods, which usually rely on strong bases and air-sensitive materials. The use of electrons as reagents results in an efficient and clean synthesis, enabling the direct application of NHCs in various fields such as organocatalysis, synthesis, and organometallic chemistry.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Chemistry, Inorganic & Nuclear
Thomas P. Nicholls, Richard A. Bourne, Bao N. Nguyen, Nikil Kapur, Charlotte E. Willans
Summary: An on-demand electrochemical synthesis of copper(I) triflate has been developed, with the only byproduct being hydrogen gas, eliminating the need for workup and purification. Water is also not incorporated into the product, allowing for direct transfer into reaction mixtures for catalytic oxidation.
INORGANIC CHEMISTRY
(2021)
Article
Multidisciplinary Sciences
Nicolas Bery, Carole J. R. Bataille, Angela Russell, Angela Hayes, Florence Raynaud, Sabine Milhas, Sneha Anand, Hanna Tulmin, Ami Miller, Terence H. Rabbitts
Summary: Intracellular antibodies can be used for target validation or developing small-molecule surrogates, such as through Abd technology. Researchers have identified a series of anti-LMO2 Abd compounds that bind to the same location as an inhibitory anti-LMO2 intracellular antibody, demonstrating potential applications in challenging protein research.
Article
Chemistry, Multidisciplinary
Christiane Schotten, Connor J. Taylor, Richard A. Bourne, Thomas W. Chamberlain, Bao N. Nguyen, Nik Kapur, Charlotte E. Willans
Summary: Synthetic electrochemistry has become an exciting technology for chemical synthesis, with alternating polarity frequency having a crucial impact on the observed reaction rate of Cu(i)-NHC complex formation, allowing for enhanced yield that is stable over extended reaction times.
REACTION CHEMISTRY & ENGINEERING
(2021)
Article
Nanoscience & Nanotechnology
Arvind K. Jain, Carole J. R. Bataille, Sabine Milhas, Ami Miller, Jing Zhang, Terry H. Rabbitts
ACS APPLIED BIO MATERIALS
(2020)
Article
Multidisciplinary Sciences
Samuel Boobier, David R. J. Hose, A. John Blacker, Bao N. Nguyen
NATURE COMMUNICATIONS
(2020)
Article
Chemistry, Inorganic & Nuclear
Natalie Fey, Alexander Koumi, Andrei V. Malkov, Jonathan D. Moseley, Bao N. Nguyen, Simon N. G. Tyler, Charlotte E. Willans
DALTON TRANSACTIONS
(2020)
Review
Chemistry, Multidisciplinary
Christiane Schotten, Thomas P. Nicholls, Richard A. Bourne, Nikil Kapur, Bao N. Nguyen, Charlotte E. Willans
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
