G-CSF maintains controlled neutrophil mobilization during acute inflammation by negatively regulating CXCR2 signaling

Autophagy is required for stem cell mobilization by G-CSF

(2015) L. Leveque-El Mouttie et al.   BLOOD

Myeloid Cell-Derived Reactive Oxygen Species Externally Regulate the Proliferation of Myeloid Progenitors in Emergency Granulopoiesis

(2015) Hyun-Jeong Kwak et al.   IMMUNITY

Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injury

(2015) Philipp Kruger et al.   PLoS Pathogens

A phase 1 clinical trial of long-term, low-dose treatment of WHIM syndrome with the CXCR4 antagonist plerixafor

(2014) D. H. McDermott et al.   BLOOD

The Balancing Act of Neutrophils

(2014) Bart W. Bardoel et al.   Cell Host & Microbe

G-CSF: From granulopoietic stimulant to bone marrow stem cell mobilizing agent

(2014) Linda J. Bendall et al.   CYTOKINE & GROWTH FACTOR REVIEWS

CD47 Deficiency Protects Mice from Lipopolysaccharide-Induced Acute Lung Injury and Escherichia coli Pneumonia

(2014) X. Su et al.   JOURNAL OF IMMUNOLOGY

Crosstalk between CXCR4/Stromal Derived Factor-1 and VLA-4/VCAM-1 Pathways Regulates Neutrophil Retention in the Bone Marrow

(2014) J. M. Petty et al.   JOURNAL OF IMMUNOLOGY

Homeostatic Regulation of Blood Neutrophil Counts

(2014) S. von Vietinghoff et al.   JOURNAL OF IMMUNOLOGY

Neutrophils at work

(2014) William M Nauseef et al.   NATURE IMMUNOLOGY

Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow

(2013) Sapna Devi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of Circulating Neutrophil Numbers under Homeostasis and in Disease

(2013) Natasha Strydom et al.   Journal of Innate Immunity

Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice

(2012) Junjie Mei et al.   JOURNAL OF CLINICAL INVESTIGATION

Leukocyte integrin activation mediates transient neutropenia after G-CSF administration

(2011) R. E. Donahue et al.   BLOOD

The CXCR4 antagonist plerixafor is a potential therapy for myelokathexis, WHIM syndrome

(2011) D. C. Dale et al.   BLOOD

The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome

(2011) D. H. McDermott et al.   BLOOD

Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model

(2011) Y. Li et al.   BLOOD

G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands

(2011) A. Kohler et al.   BLOOD

Regulation of neutrophil trafficking from the bone marrow

(2011) Ryan B. Day et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Twenty years of the colony-stimulating factors

(2011) David C. Dale   CURRENT OPINION IN HEMATOLOGY

G-CSF enhances the proliferation and mobilization, but not the maturation rate, of murine myeloid cells

(2011) Eirunn Knudsen et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Neutrophils cascading their way to inflammation

(2011) Christian D. Sadik et al.   TRENDS IN IMMUNOLOGY

Neutrophil clearance: when the party is over, clean-up begins

(2011) Donna L. Bratton et al.   TRENDS IN IMMUNOLOGY

Neutralizing Granulocyte/Macrophage Colony–Stimulating Factor Inhibits Cigarette Smoke–induced Lung Inflammation

(2010) Ross Vlahos et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Transient neutropenia after granulocyte-colony stimulating factor administration is associated with neutrophil accumulation in pulmonary vasculature

(2010) Catherine E. DeJesus et al.   EXPERIMENTAL HEMATOLOGY

CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow

(2010) Kyle J. Eash et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms of G-CSF-mediated hematopoietic stem and progenitor mobilization

(2010) A M Greenbaum et al.   LEUKEMIA

Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia

(2009) Y. Li et al.   BLOOD

CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions

(2009) Kyle J. Eash et al.   BLOOD

Chemokines in hematopoiesis

(2009) Hal E Broxmeyer   CURRENT OPINION IN HEMATOLOGY

G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis

(2009) Ann L. Cornish et al.   Nature Reviews Rheumatology

A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis

(2008) J. L. Eyles et al.   BLOOD

Dynamics of Neutrophil Migration in Lymph Nodes during Infection

(2008) Tatyana Chtanova et al.   IMMUNITY

Neutrophil mobilization and clearance in the bone marrow

(2008) Rebecca C. Furze et al.   IMMUNOLOGY

PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils

(2008) Bryan Heit et al.   NATURE IMMUNOLOGY

In Vivo Imaging Reveals an Essential Role for Neutrophils in Leishmaniasis Transmitted by Sand Flies

(2008) N. C. Peters et al.   SCIENCE