Regulation of neutrophil trafficking from the bone marrow

G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands

(2011) A. Kohler et al.   BLOOD

SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans

(2011) Aili L. Lazaar et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice

(2011) Matthew J. Christopher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil Mobilization from the Bone Marrow during Polymicrobial Sepsis Is Dependent on CXCL12 Signaling

(2011) M. J. Delano et al.   JOURNAL OF IMMUNOLOGY

Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression

(2010) Y.-S. Tzeng et al.   BLOOD

Live imaging of neutrophil motility in a zebrafish model of WHIM syndrome

(2010) K. B. Walters et al.   BLOOD

Site-specific Phosphorylation of CXCR4 Is Dynamically Regulated by Multiple Kinases and Results in Differential Modulation of CXCR4 Signaling

(2010) John M. Busillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow

(2010) Kyle J. Eash et al.   JOURNAL OF CLINICAL INVESTIGATION

CXCR7 Protein Is Not Expressed on Human or Mouse Leukocytes

(2010) R. D. Berahovich et al.   JOURNAL OF IMMUNOLOGY

The bone marrow: a site of neutrophil clearance

(2010) S. M. Rankin   JOURNAL OF LEUKOCYTE BIOLOGY

Chemokines and chemokine receptors: new insights into cancer-related inflammation

(2010) Gwendal Lazennec et al.   TRENDS IN MOLECULAR MEDICINE

CXCR4 antagonist AMD3100 attenuates colonic damage in mice with experimental colitis

(2010) Xian-Ming Xia   WORLD JOURNAL OF GASTROENTEROLOGY

Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization

(2009) M. J. Christopher et al.   BLOOD

CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions

(2009) Kyle J. Eash et al.   BLOOD

SB265610 is an allosteric, inverse agonist at the human CXCR2 receptor

(2009) ME Bradley et al.   BRITISH JOURNAL OF PHARMACOLOGY

Genetic etiologies of leukocyte adhesion defects

(2009) Amos Etzioni   CURRENT OPINION IN IMMUNOLOGY

SCH527123, a novel CXCR2 antagonist, inhibits ozone-induced neutrophilia in healthy subjects

(2009) O. Holz et al.   EUROPEAN RESPIRATORY JOURNAL

Impaired Recruitment of Grk6 and β-Arrestin2 Causes Delayed Internalization and Desensitization of a WHIM Syndrome-Associated CXCR4 Mutant Receptor

(2009) Peter J. McCormick et al.   PLoS One

CXCR4 dimerization and  -arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome

(2008) B. Lagane et al.   BLOOD

Migration across the sinusoidal endothelium regulates neutrophil mobilization in response to ELR + CXC chemokines

(2008) Peter C. E. Burdon et al.   BRITISH JOURNAL OF HAEMATOLOGY

WHIM syndrome: congenital immune deficiency disease

(2008) Toshinao Kawai et al.   CURRENT OPINION IN HEMATOLOGY

Neutrophil mobilization and clearance in the bone marrow

(2008) Rebecca C. Furze et al.   IMMUNOLOGY

CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers

(2008) J A Burger et al.   LEUKEMIA