Mechanisms of G-CSF-mediated hematopoietic stem and progenitor mobilization

Kit Regulates Maintenance of Quiescent Hematopoietic Stem Cells

(2014) L. A. Thoren et al.   JOURNAL OF IMMUNOLOGY

Higher incidence of relapse in patients with acute myelocytic leukemia infused with higher doses of CD34+ cells from leukapheresis products autografted during the first remission

(2010) N.-C. Gorin et al.   BLOOD

Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF-1/CXCR4 axis: Further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells

(2010) Ali Jalili et al.   EXPERIMENTAL HEMATOLOGY

CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow

(2010) Kyle J. Eash et al.   JOURNAL OF CLINICAL INVESTIGATION

Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex

(2010) M Z Ratajczak et al.   LEUKEMIA

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells

(2009) P. Ramirez et al.   BLOOD

Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization

(2009) M. J. Christopher et al.   BLOOD

Higher Incidence of Relapse With Peripheral Blood Rather Than Marrow As a Source of Stem Cells in Adults With Acute Myelocytic Leukemia Autografted During the First Remission

(2009) Norbert-Claude Gorin et al.   JOURNAL OF CLINICAL ONCOLOGY

Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow

(2009) Satoru Morikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes

(2009) H M Lee et al.   LEUKEMIA

The monoclonal anti-VLA-4 antibody natalizumab mobilizes CD34+ hematopoietic progenitor cells in humans

(2008) F. Zohren et al.   BLOOD

Plasmin therapy enhances mobilization of HPCs after G-CSF

(2008) M. Tjwa et al.   BLOOD

Control of Chemokine-Guided Cell Migration by Ligand Sequestration

(2008) Bijan Boldajipour et al.   CELL

Secreted Trefoil Factor 2 Activates the CXCR4 Receptor in Epithelial and Lymphocytic Cancer Cell Lines

(2008) Zinaida Dubeykovskaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Granulocyte Colony-Stimulating Factor Induces Osteoblast Apoptosis and Inhibits Osteoblast Differentiation

(2008) Matthew J Christopher et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells

(2008) Tanja Nicole Hartmann et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

(2008) Cristina Lo Celso et al.   NATURE

Detection of functional haematopoietic stem cell niche using real-time imaging

(2008) Yucai Xie et al.   NATURE

Haematopoietic stem cell release is regulated by circadian oscillations

(2008) Simón Méndez-Ferrer et al.   NATURE

A Novel Role for PECAM-1 (CD31) in Regulating Haematopoietic Progenitor Cell Compartmentalization between the Peripheral Blood and Bone Marrow

(2008) Ewan A. Ross et al.   PLoS One

Carboxypeptidase M Expressed by Human Bone Marrow Cells Cleaves the C-Terminal Lysine of Stromal Cell-Derived Factor-1α: Another Player in Hematopoietic Stem/Progenitor Cell Mobilization?

(2008) Leah Marquez-Curtis et al.   STEM CELLS