Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis

Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases

(2020) Sylvia T. Nurnberg et al.   PLoS Genetics

The mutational constraint spectrum quantified from variation in 141,456 humans

(2020) Konrad J. Karczewski et al.   NATURE

CARMAL Is a Long Non-coding RNA Locus That Regulates MFGE8 Expression

(2020) Sébastien Soubeyrand et al.   Frontiers in Genetics

2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

(2020) Jean-Philippe Collet et al.   EUROPEAN HEART JOURNAL

MFG-E8 overexpression is associated with poor prognosis in breast cancer patients

(2019) Lifeng Yu et al.   PATHOLOGY RESEARCH AND PRACTICE

Regulation of MFGE8 by the intergenic coronary artery disease locus on 15q26.1

(2019) Sébastien Soubeyrand et al.   ATHEROSCLEROSIS

AlphaFold at CASP13

(2019) Mohammed AlQuraishi   BIOINFORMATICS

Atherosclerosis

(2019) Peter Libby et al.   Nature Reviews Disease Primers

Immunoregulatory influence of abundant MFG-E8 expression by esophageal cancer treated with chemotherapy

(2018) Takashi Kanemura et al.   CANCER SCIENCE

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

(2018) Wei Zhou et al.   NATURE GENETICS

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

(2018) Evangelos Evangelou et al.   NATURE GENETICS

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel

(2017) Mario Mitt et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Overview of the BioBank Japan Project: Study design and profile

(2017) Akiko Nagai et al.   JOURNAL OF EPIDEMIOLOGY

Control for Population Structure and Relatedness for Binary Traits in Genetic Association Studies via Logistic Mixed Models

(2016) Han Chen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

FINEMAP: efficient variable selection using summary data from genome-wide association studies

(2016) Christian Benner et al.   BIOINFORMATICS

Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation

(2016) Thomas J Hoffmann et al.   NATURE GENETICS

Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease

(2016) Frederick E. Dewey et al.   NEW ENGLAND JOURNAL OF MEDICINE

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Forty-year trends in cardiovascular risk factors in Finland

(2014) K. Borodulin et al.   EUROPEAN JOURNAL OF PUBLIC HEALTH

Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu

(2014) Liis Leitsalu et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Lipid lowering with PCSK9 inhibitors

(2014) Razvan T. Dadu et al.   Nature Reviews Cardiology

Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

Milk Fat Globule Epidermal Growth Factor VIII Signaling in Arterial Wall Remodeling

(2013) Mingyi Wang et al.   Current Vascular Pharmacology

MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

(2013) Nicolas Deroide et al.   JOURNAL OF CLINICAL INVESTIGATION

Meta-analysis methods for genome-wide association studies and beyond

(2013) Evangelos Evangelou et al.   NATURE REVIEWS GENETICS

Genetics of Coronary Artery Disease and Myocardial Infarction - 2013

(2013) Thorsten Kessler et al.   Current Cardiology Reports

Mortality and Cardiovascular Events Are Best Predicted by Low Central/Peripheral Pulse Pressure Amplification But Not by High Blood Pressure Levels in Elderly Nursing Home Subjects

(2012) Athanase Benetos et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cohort Profile: The Corogene study

(2011) Satu Vaara et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Clinical usefulness of novel prognostic biomarkers in patients on hemodialysis

(2011) Alberto Ortiz et al.   Nature Reviews Nephrology

Recombinant human MFG-E8 attenuates cerebral ischemic injury: Its role in anti-inflammation and anti-apoptosis

(2011) Cletus Cheyuo et al.   NEUROPHARMACOLOGY

Genomics of Cardiovascular Disease

(2011) Christopher J. O'Donnell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Arterial aging: a journey into subclinical arterial disease

(2010) Mingyi Wang et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Milk fat globule—epidermal growth factor—factor VIII (MFGE8)/lactadherin promotes bladder tumor development

(2010) G Sugano et al.   ONCOGENE

Comparative proteomic analysis of rat aorta in a subtotal nephrectomy model

(2010) Yao-Ping Lin et al.   PROTEOMICS

Milk Fat Globule Protein Epidermal Growth Factor-8

(2009) Zongming Fu et al.   CIRCULATION RESEARCH

SED1/MFG-E8: A Bi-Motif protein that orchestrates diverse cellular interactions

(2009) Adam Raymond et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Quantification of Protein Expression Changes in the Aging Left Ventricle ofRattus norvegicus

(2009) Jennifer E. Grant et al.   JOURNAL OF PROTEOME RESEARCH

Emerging concepts in biomarker discovery; The US-Japan workshop on immunological molecular markers in oncology

(2009) Hideaki Tahara et al.   Journal of Translational Medicine

Milk Fat Globule EGF-8 Promotes Melanoma Progression through Coordinated Akt and Twist Signaling in the Tumor Microenvironment

(2008) Masahisa Jinushi et al.   CANCER RESEARCH

Cohort Profile: The Cardiovascular Risk in Young Finns Study

(2008) O. T Raitakari et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry

(2008) Gianluca Picariello et al.   PROTEOMICS