Beyond antibacterials – exploring bacteriophages as antivirulence agents

Fitness trade-offs resulting from bacteriophage resistance potentiate synergistic antibacterial strategies

(2020) Mihnea R. Mangalea et al.   INFECTION AND IMMUNITY

The arms race between bacteria and their phage foes

(2020) Hannah G. Hampton et al.   NATURE

Diversity and Function of Phage Encoded Depolymerases

(2020) Leandra E. Knecht et al.   Frontiers in Microbiology

Glycotyping and specific separation of Listeria monocytogenes with a novel bacteriophage protein toolkit

(2020) Eric T. Sumrall et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Tailspike with EPS-depolymerase activity, encoded by a phage belonging to a new genus, makes Providencia stuartii susceptible to serum-mediated killing

(2020) Hugo Oliveira et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Galactosylated wall teichoic acid, but not lipoteichoic acid, retains InlB on the surface of serovar 4b Listeria monocytogenes

(2020) Eric T. Sumrall et al.   MOLECULAR MICROBIOLOGY

Pleiotropy complicates a trade-off between phage resistance and antibiotic resistance

(2020) Alita R. Burmeister et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phase-variable capsular polysaccharides and lipoproteins modify bacteriophage susceptibility in Bacteroides thetaiotaomicron

(2020) Nathan T. Porter et al.   Nature Microbiology

Phage Therapy in the Postantibiotic Era

(2019) Fernando L. Gordillo Altamirano et al.   CLINICAL MICROBIOLOGY REVIEWS

Structure and transformation of bacteriophage A511 baseplate and tail upon infection of Listeria cells

(2019) Ricardo C Guerrero‐Ferreira et al.   EMBO JOURNAL

Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection

(2019) Johanna M. Sweere et al.   SCIENCE

Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis

(2019) Lasha Gogokhia et al.   Cell Host & Microbe

Bacteriophage Resistance Alters Antibiotic-Mediated Intestinal Expansion of Enterococci

(2019) Anushila Chatterjee et al.   INFECTION AND IMMUNITY

Three Capsular Polysaccharide Synthesis-Related Glucosyltransferases, GT-1, GT-2 and WcaJ, Are Associated With Virulence and Phage Sensitivity of Klebsiella pneumoniae

(2019) Ruopeng Cai et al.   Frontiers in Microbiology

A specific sugar moiety in the Lactococcus lactis cell wall pellicle is required for infection by CHPC971, a member of the rare 1706 phage species.

(2019) Barbara Marcelli et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Structural Basis for Cell-Wall Recognition by Bacteriophage PBC5 Endolysin

(2019) Ko On Lee et al.   STRUCTURE

Structure and tailspike glycosidase machinery of ORF212 from E. coli O157:H7 phage CBA120 (TSP3)

(2019) Julia Greenfield et al.   Scientific Reports

Stronger together? Perspectives on phage-antibiotic synergy in clinical applications of phage therapy

(2019) Anca M Segall et al.   CURRENT OPINION IN MICROBIOLOGY

The Vibrio cholerae minor pilin TcpB mediates uptake of the cholera toxin phage CTXφ

(2019) Miguel Gutierrez-Rodarte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Steering Phages to Combat Bacterial Pathogens

(2019) James Gurney et al.   TRENDS IN MICROBIOLOGY

Capsular Polysaccharide Is a Receptor of a Clostridium perfringens Bacteriophage CPS1

(2019) Eunsu Ha et al.   Viruses-Basel

Reprogramming Bacteriophage Host Range through Structure-Guided Design of Chimeric Receptor Binding Proteins

(2019) Matthew Dunne et al.   Cell Reports

Phage resistance at the cost of virulence: Listeria monocytogenes serovar 4b requires galactosylated teichoic acids for InlB-mediated invasion

(2019) Eric T. Sumrall et al.   PLoS Pathogens

A Novel Polysaccharide Depolymerase Encoded by the Phage SH-KP152226 Confers Specific Activity Against Multidrug-Resistant Klebsiella pneumoniae via Biofilm Degradation

(2019) Yunqiang Wu et al.   Frontiers in Microbiology

More than rotating flagella: LPS as a secondary receptor for flagellotropic phage 7-7-1

(2018) Floricel Gonzalez et al.   JOURNAL OF BACTERIOLOGY

Glycointeractions in bacterial pathogenesis

(2018) Jessica Poole et al.   NATURE REVIEWS MICROBIOLOGY

Cross-genus rebooting of custom-made, synthetic bacteriophage genomes in L-form bacteria

(2018) Samuel Kilcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and Characterization of Type IV Pili as the Cellular Receptor of Broad Host Range Stenotrophomonas maltophilia Bacteriophages DLP1 and DLP2

(2018) Jaclyn McCutcheon et al.   Viruses-Basel

Resistance Development to Bacteriophages Occurring during Bacteriophage Therapy

(2018) Frank Oechslin   Viruses-Basel

Phase Variable Expression of a Single Phage Receptor in Campylobacter jejuni NCTC12662 Influences Sensitivity Toward Several Diverse CPS-Dependent Phages

(2018) Yilmaz Emre Gencay et al.   Frontiers in Microbiology

Loss-of-Function Mutations in epaR Confer Resistance to ϕNPV1 Infection in Enterococcus faecalis OG1RF

(2018) Khang Ho et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cell wall glycans mediate recognition of the dairy bacterium Streptococcus thermophilus by bacteriophages

(2018) Paula Szymczak et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Targeting mechanisms of tailed bacteriophages

(2018) Franklin L. Nobrega et al.   NATURE REVIEWS MICROBIOLOGY

Molecular Basis of Bacterial Host Interactions by Gram-Positive Targeting Bacteriophages

(2018) Matthew Dunne et al.   Viruses-Basel

Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System

(2018) Jonas Van Belleghem et al.   Viruses-Basel

Phage-Borne Depolymerases Decrease Klebsiella pneumoniae Resistance to Innate Defense Mechanisms

(2018) Grazyna Majkowska-Skrobek et al.   Frontiers in Microbiology

Lysogeny in nature: mechanisms, impact and ecology of temperate phages

(2017) Cristina Howard-Varona et al.   ISME Journal

The outer-membrane protein TolC ofVibrio choleraeserves as a second cell-surface receptor for the VP3 phage

(2017) Fenxia Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and functional diversity inListeriacell wall teichoic acids

(2017) Yang Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fine structure analysis of lipopolysaccharides in bacteriophage-resistant Pseudomonas aeruginosa PAO1 mutants

(2017) Libera Latino et al.   MICROBIOLOGY-SGM

Pseudomonas aeruginosa defends against phages through type IV pilus glycosylation

(2017) Hanjeong Harvey et al.   Nature Microbiology

Wall teichoic acids mediate increased virulence in Staphylococcus aureus

(2017) Stefanie Wanner et al.   Nature Microbiology

The O-specific polysaccharide lyase from the phage LKA1 tailspike reduces Pseudomonas virulence

(2017) Tomasz Olszak et al.   Scientific Reports

Phage selection restores antibiotic sensitivity in MDR Pseudomonas aeruginosa

(2016) Benjamin K. Chan et al.   Scientific Reports

Characterization of Wall Teichoic Acid Degradation by the Bacteriophage ϕ29 Appendage Protein GP12 Using Synthetic Substrate Analogs

(2015) Cullen L. Myers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the Pre-neck Appendage Protein (Dpo7) from Phage vB_SepiS-phiIPLA7 as an Anti-biofilm Agent in Staphylococcal Species

(2015) Diana Gutiérrez et al.   Frontiers in Microbiology

The tail-associated depolymerase ofErwinia amylovoraphage L1 mediates host cell adsorption and enzymatic capsule removal, which can enhance infection by other phage

(2013) Yannick Born et al.   ENVIRONMENTAL MICROBIOLOGY