Mapping phenotypic heterogeneity in melanoma onto the epithelial-hybrid-mesenchymal axis
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mapping phenotypic heterogeneity in melanoma onto the epithelial-hybrid-mesenchymal axis
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2022-08-08
DOI
10.3389/fonc.2022.913803
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Interconnected high-dimensional landscapes of epithelial–mesenchymal plasticity and stemness in cancer
- (2022) Sarthak Sahoo et al. CLINICAL & EXPERIMENTAL METASTASIS
- Quantifying the Patterns of Metabolic Plasticity and Heterogeneity along the Epithelial–Hybrid–Mesenchymal Spectrum in Cancer
- (2022) Srinath Muralidharan et al. Biomolecules
- Intermittent treatment of BRAF V600E melanoma cells delays resistance by adaptive resensitization to drug rechallenge
- (2022) Andrew J. Kavran et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrin-linked kinase tunes cell-cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1
- (2021) Ayse Nihan Kilinc et al. MOLECULAR BIOLOGY OF THE CELL
- MITF reprograms the extracellular matrix and focal adhesion in melanoma
- (2021) Ramile Dilshat et al. eLife
- A Computational Systems Biology Approach Identifies SLUG as a Mediator of Partial Epithelial-Mesenchymal Transition (EMT)
- (2021) Ayalur R. Subbalakshmi et al. CELLS TISSUES ORGANS
- Measuring and Modelling the Epithelial- Mesenchymal Hybrid State in Cancer: Clinical Implications
- (2021) Mohit Kumar Jolly et al. CELLS TISSUES ORGANS
- A Theoretical Approach to Coupling the Epithelial-Mesenchymal Transition (EMT) to Extracellular Matrix (ECM) Stiffness via LOXL2
- (2021) Youyuan Deng et al. Cancers
- Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation
- (2021) Nathaniel R. Campbell et al. DEVELOPMENTAL CELL
- Calcium signaling induces a partial EMT
- (2021) Robert J Norgard et al. EMBO REPORTS
- How Neural Crest Transcription Factors Contribute to Melanoma Heterogeneity, Cellular Plasticity, and Treatment Resistance
- (2021) Anja Wessely et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Phenotypic plasticity of melanocytes derived from human adult skin
- (2021) Dániel László Vidács et al. Pigment Cell & Melanoma Research
- KLF4 Induces Mesenchymal–Epithelial Transition (MET) by Suppressing Multiple EMT-Inducing Transcription Factors
- (2021) Ayalur Raghu Subbalakshmi et al. Cancers
- Systems-level network modeling deciphers the master regulators of phenotypic plasticity and heterogeneity in melanoma
- (2021) Maalavika Pillai et al. iScience
- Glucose Metabolism Takes Center Stage in Epithelial-Mesenchymal Plasticity
- (2020) Khalil Kass Youssef et al. DEVELOPMENTAL CELL
- Context specificity of the EMT transcriptional response
- (2020) David P. Cook et al. Nature Communications
- Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line
- (2020) Yapeng Su et al. Nature Communications
- The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype
- (2020) Niels Vandamme et al. CANCER RESEARCH
- Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex
- (2020) Laurent Fattet et al. DEVELOPMENTAL CELL
- Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma
- (2020) Jasper Wouters et al. NATURE CELL BIOLOGY
- Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy
- (2020) Charles P. Couturier et al. Nature Communications
- EMT-Inducing Transcription Factors, Drivers of Melanoma Phenotype Switching, and Resistance to Treatment
- (2020) Yaqi Tang et al. Cancers
- An Unsupervised Strategy for Identifying Epithelial-Mesenchymal Transition State Metrics in Breast Cancer and Melanoma
- (2020) David J. Klinke et al. iScience
- The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
- (2020) Christina Jessen et al. ONCOGENE
- NFATc Acts as a Non-Canonical Phenotypic Stability Factor for a Hybrid Epithelial/Mesenchymal Phenotype
- (2020) Ayalur Raghu Subbalakshmi et al. Frontiers in Oncology
- Drug-Tolerant Idling Melanoma Cells Exhibit Theory-Predicted Metabolic Low-Low Phenotype
- (2020) Dongya Jia et al. Frontiers in Oncology
- Hybrid E/M Phenotype(s) and Stemness: A Mechanistic Connection Embedded in Network Topology
- (2020) Satwik Pasani et al. Journal of Clinical Medicine
- Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells
- (2019) Cornelia Kröger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An actionable axis linking NFATc2 to EZH2 controls the EMT-like program of melanoma cells
- (2019) Valentina Perotti et al. ONCOGENE
- E-cadherin represses anchorage-independent growth in sarcomas through both signaling and mechanical mechanisms
- (2019) Mohit Kumar Jolly et al. MOLECULAR CANCER RESEARCH
- Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation
- (2019) Jason E. Long et al. CELL DEATH AND DIFFERENTIATION
- Proneural-Mesenchymal Transition: Phenotypic Plasticity to Acquire Multitherapy Resistance in Glioblastoma
- (2019) Monica Fedele et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities
- (2019) Florian Rambow et al. GENES & DEVELOPMENT
- The phenotypes of proliferating glioblastoma cells reside on a single axis of variation
- (2019) Lin Wang et al. Cancer Discovery
- Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity
- (2019) Yurena Vivas-García et al. MOLECULAR CELL
- Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress
- (2018) Jennifer Tsoi et al. CANCER CELL
- Toward Minimal Residual Disease-Directed Therapy in Melanoma
- (2018) Florian Rambow et al. CELL
- Collagen abundance controls melanoma phenotypes through lineage-specific microenvironment sensing
- (2018) Zsofia Miskolczi et al. ONCOGENE
- Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression
- (2018) Dongmei Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility
- (2018) Amanpreet Kaur et al. Cancer Discovery
- uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells
- (2017) Anna Laurenzana et al. INTERNATIONAL JOURNAL OF CANCER
- EMT- and MET-related processes in nonepithelial tumors: importance for disease progression, prognosis, and therapeutic opportunities
- (2017) Ulf D. Kahlert et al. Molecular Oncology
- EMT and inflammation: inseparable actors of cancer progression
- (2017) Meggy Suarez-Carmona et al. Molecular Oncology
- Super-enhancers define a proliferative PGC-1α-expressing melanoma subgroup sensitive to BET inhibition
- (2017) K A Gelato et al. ONCOGENE
- Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance
- (2017) Yapeng Su et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome
- (2016) Vaia Stavropoulou et al. CANCER CELL
- Mesenchymal-Epithelial Transition in Sarcomas Is Controlled by the Combinatorial Expression of MicroRNA 200s and GRHL2
- (2016) Jason A. Somarelli et al. MOLECULAR AND CELLULAR BIOLOGY
- Stability of the hybrid epithelial/mesenchymal phenotype
- (2016) Mohit Kumar Jolly et al. Oncotarget
- Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation
- (2016) Xinde Zheng et al. eLife
- Metabolic reprogramming supports the invasive phenotype in malignant melanoma
- (2015) Ingrid J. Bettum et al. CANCER LETTERS
- Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP/TAZ activation
- (2015) M. H. Kim et al. EMBO JOURNAL
- Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival
- (2015) Anne Grosse-Wilde et al. PLoS One
- Molecular drivers of cellular metabolic reprogramming in melanoma
- (2015) Cecilie Abildgaard et al. TRENDS IN MOLECULAR MEDICINE
- Temporally sequenced anticancer drugs overcome adaptive resistance by targeting a vulnerable chemotherapy-induced phenotypic transition
- (2015) Aaron Goldman et al. Nature Communications
- Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state
- (2015) Annelien Verfaillie et al. Nature Communications
- CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation
- (2015) Aldo M. Roccaro et al. Cell Reports
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression
- (2014) G Denecker et al. CELL DEATH AND DIFFERENTIATION
- Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients
- (2014) T. Z. Tan et al. EMBO Molecular Medicine
- Extracellular matrix density promotes EMT by weakening cell–cell adhesions
- (2014) Sandeep Kumar et al. Molecular BioSystems
- Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts
- (2014) Suling Liu et al. Stem Cell Reports
- A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma
- (2013) Julie Caramel et al. CANCER CELL
- PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress
- (2013) Francisca Vazquez et al. CANCER CELL
- Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
- (2013) Rizwan Haq et al. CANCER CELL
- The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma
- (2013) E Sánchez-Tilló et al. CELL DEATH AND DIFFERENTIATION
- The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance
- (2013) Florian A. Siebzehnrubl et al. EMBO Molecular Medicine
- Human Melanoma Cells Over-Express Extracellular Matrix 1 (ECM1) Which Is Regulated by TFAP2C
- (2013) Geeta Lal et al. PLoS One
- An Epithelial-Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
- (2012) L. A. Byers et al. CLINICAL CANCER RESEARCH
- Biological roles and prognostic values of the epithelial-mesenchymal transition-mediating transcription factors Twist, ZEB1 and Slug in diffuse large B-cell lymphoma
- (2012) Siria Lemma et al. HISTOPATHOLOGY
- N-cadherin expression level modulates integrin-mediated polarity and strongly impacts on the speed and directionality of glial cell migration
- (2012) Emeline Camand et al. JOURNAL OF CELL SCIENCE
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
- (2012) Jordi Barretina et al. NATURE
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Role of β5-integrin in epithelial-mesenchymal transition in response to TGF-β
- (2011) Anna Bianchi et al. CELL CYCLE
- Matrix Metalloproteinase-Induced Epithelial-Mesenchymal Transition in Breast Cancer
- (2010) Evette S. Radisky et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
- (2009) David A. Barbie et al. NATURE
- In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States
- (2008) K. S. Hoek et al. CANCER RESEARCH
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started