Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6

Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPAR -driven enhancers

(2014) S. E. Step et al.   GENES & DEVELOPMENT

Enhancer RNA Facilitates NELF Release from Immediate Early Genes

(2014) Katie Schaukowitch et al.   MOLECULAR CELL

BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones

(2014) Tomohiko Kanno et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Jumonji domain containing protein 6 (Jmjd6) modulates splicing and specifically interacts with arginine–serine-rich (RS) domains of SR- and SR-like proteins

(2014) Astrid Heim et al.   NUCLEIC ACIDS RESEARCH

JMJD6 Regulates ERα Methylation on Arginine

(2014) Coralie Poulard et al.   PLoS One

Enhancer RNAs and regulated transcriptional programs

(2014) Michael T.Y. Lam et al.   TRENDS IN BIOCHEMICAL SCIENCES

The roles of Jumonji-type oxygenases in human disease

(2014) Catrine Johansson et al.   Epigenomics

Transcription Factor Cooperativity in Early Adipogenic Hotspots and Super-Enhancers

(2014) Rasmus Siersbæk et al.   Cell Reports

Rictor/mTORC2 Loss in the Myf5 Lineage Reprograms Brown Fat Metabolism and Protects Mice against Obesity and Metabolic Disease

(2014) Chien-Min Hung et al.   Cell Reports

JMJD6 Promotes Colon Carcinogenesis through Negative Regulation of p53 by Hydroxylation

(2014) Feng Wang et al.   PLOS BIOLOGY

The polyserine domain of the lysyl-5 hydroxylase Jmjd6 mediates subnuclear localization

(2013) Alexander Wolf et al.   BIOCHEMICAL JOURNAL

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

(2013) Jakob Lovén et al.   CELL

Brd4 and JMJD6-Associated Anti-Pause Enhancers in Regulation of Transcriptional Pause Release

(2013) Wen Liu et al.   CELL

Lysyl 5-Hydroxylation, a Novel Histone Modification, by Jumonji Domain Containing 6 (JMJD6)

(2013) Motoko Unoki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity, adiposity, and dyslipidemia: A consensus statement from the National Lipid Association

(2013) Harold E. Bays et al.   Journal of Clinical Lipidology

BRD4 Coordinates Recruitment of Pause Release Factor P-TEFb and the Pausing Complex NELF/DSIF To Regulate Transcription Elongation of Interferon-Stimulated Genes

(2013) M. C. Patel et al.   MOLECULAR AND CELLULAR BIOLOGY

Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting

(2013) Shwu-Yuan Wu et al.   MOLECULAR CELL

eRNAs Promote Transcription by Establishing Chromatin Accessibility at Defined Genomic Loci

(2013) Kambiz Mousavi et al.   MOLECULAR CELL

Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation

(2013) Wenbo Li et al.   NATURE

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

(2013) Qiong A Wang et al.   NATURE MEDICINE

The Scaffold attachment factor b1 (Safb1) regulates myogenic differentiation by facilitating the transition of myogenic gene chromatin from a repressed to an activated state

(2013) J. M. Hernandez-Hernandez et al.   NUCLEIC ACIDS RESEARCH

Brd2 Inhibits Adipogenesis via the ERK1/2 Signaling Pathway in 3T3-L1 Adipocytes

(2013) Kun Zang et al.   PLoS One

Extensive chromatin remodelling and establishment of transcription factor ‘hotspots’ during early adipogenesis

(2011) Rasmus Siersbaek et al.   EMBO JOURNAL

The Brd4 Extraterminal Domain Confers Transcription Activation Independent of pTEFb by Recruiting Multiple Proteins, Including NSD3

(2011) S. Rahman et al.   MOLECULAR AND CELLULAR BIOLOGY

Forming functional fat: a growing understanding of adipocyte differentiation

(2011) Ana G. Cristancho et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1

(2011) J.-N. Boeckel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6

(2011) Monica Mantri et al.   MedChemComm

Propagation of adipogenic signals through an epigenomic transition state

(2010) D. J. Steger et al.   GENES & DEVELOPMENT

Selective inhibition of BET bromodomains

(2010) Panagis Filippakopoulos et al.   NATURE

Analysis of Jmjd6 Cellular Localization and Testing for Its Involvement in Histone Demethylation

(2010) Phillip Hahn et al.   PLoS One

Interaction of JMJD6 with single-stranded RNA

(2010) X. Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases

(2010) Christoph Loenarz et al.   TRENDS IN BIOCHEMICAL SCIENCES

Inflammation and impaired adipogenesis in hypertrophic obesity in man

(2009) Birgit Gustafson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Brd2disruption in mice causes severe obesity without Type 2 diabetes

(2009) Fangnian Wang et al.   BIOCHEMICAL JOURNAL

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

(2009) Eric Campeau et al.   PLoS One

Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing

(2009) Celia J. Webby et al.   SCIENCE

Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins

(2008) Phillip Hahn et al.   BMC GENOMICS

Genome-wide profiling of PPAR :RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis

(2008) R. Nielsen et al.   GENES & DEVELOPMENT

PPAR  and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

(2008) M. I. Lefterova et al.   GENES & DEVELOPMENT

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

(2008) P. A.C. Cloos et al.   GENES & DEVELOPMENT

The Double Bromodomain Proteins Brd2 and Brd3 Couple Histone Acetylation to Transcription

(2008) Gary LeRoy et al.   MOLECULAR CELL

Dynamics of fat cell turnover in humans

(2008) Kirsty L. Spalding et al.   NATURE