Cough hypersensitivity and chronic cough

Prevalence of chronic cough in China: a systematic review and meta-analysis

(2022) Hanwen Liang et al.   BMC Pulmonary Medicine

Efficacy and safety of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials

(2022) Lorcan P McGarvey et al.   LANCET

Cough Hypersensitivity and Suppression in Chronic Obstructive Pulmonary Disease

(2021) Peter S P Cho et al.   EUROPEAN RESPIRATORY JOURNAL

Intra-Arterial, but Not Intrathecal, Baclofen and Codeine Attenuates Cough in the Cat

(2021) Wendy L. Olsen et al.   Frontiers in Physiology

Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker

(2021) Ivan Tochitsky et al.   BRITISH JOURNAL OF PHARMACOLOGY

Glial activation and inflammation in the NTS in a rat model after exposure to diesel exhaust particles

(2021) Zhe Chen et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The spectrum, clinical features and diagnosis of chronic cough due to rare causes

(2021) Kefang Lai et al.   Journal of Thoracic Disease

Confronting COVID-19-associated cough and the post-COVID syndrome: role of viral neurotropism, neuroinflammation, and neuroimmune responses

(2021) Woo-Jung Song et al.   Lancet Respiratory Medicine

Advances in TRP channel drug discovery: from target validation to clinical studies

(2021) Ari-Pekka Koivisto et al.   NATURE REVIEWS DRUG DISCOVERY

Modulation of Vagal Sensory Neurons via High Mobility Group Box-1 and Receptor for Advanced Glycation End Products: Implications for Respiratory Viral Infections

(2021) Stuart B. Mazzone et al.   Frontiers in Physiology

Prevalence and Burden of Chronic Cough in the United States

(2021) Eli O. Meltzer et al.   Journal of Allergy and Clinical Immunology-In Practice

Children’s Acute Cough-Specific Quality of Life: Revalidation and Development of a Short Form

(2021) Sophie Anderson-James et al.   LUNG

Heartburn as a Marker of the Success of Acid Suppression Therapy in Chronic Cough

(2021) H. Badri et al.   LUNG

Effect of centrally and peripherally acting GABAB agonism on the healthy human cough reflex

(2021) Huda Badri et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Risk factors for chronic cough in adults: A systematic review and meta‐analysis

(2021) Jingwen Zhang et al.   RESPIROLOGY

A descending pathway emanating from the periaqueductal gray mediates the development of cough-like hypersensitivity

(2021) Zhe Chen et al.   iScience

Cerebellar ataxia, neuropathy, vestibular areflexia syndrome due to RFC1 repeat expansion

(2020) Andrea Cortese et al.   BRAIN

Managing Chronic Cough due to Asthma and NAEB in Adults and Adolescents

(2020) Andreanne Côté et al.   CHEST

Activation of a nerve injury transcriptional signature in airway-innervating sensory neurons after lipopolysaccharide-induced lung inflammation

(2020) Melanie Maya Kaelberer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Managing Chronic Cough as a Symptom in Children and Management Algorithms

(2020) Anne B. Chang et al.   CHEST

A role for neurokinin 1 receptor expressing neurons in the paratrigeminal nucleus in bradykinin‐evoked cough in guinea‐pigs

(2020) Alexandria K. Driessen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cough in hypereosinophilic syndrome: case report and literature review

(2020) Jiaxing Xie et al.   BMC Pulmonary Medicine

Cough persistence in adults with chronic cough: A 4-year retrospective cohort study

(2020) Sung-Yoon Kang et al.   ALLERGOLOGY INTERNATIONAL

Life-Threatening and Non-Life-Threatening Complications Associated With Coughing

(2020) Richard S. Irwin et al.   CHEST

Mechanisms and Rationale for Targeted Therapies in Refractory and Unexplained Chronic Cough

(2020) Stuart Mazzone et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Back to the future: re-establishing guinea pig in vivo asthma models

(2020) Mikael Adner et al.   CLINICAL SCIENCE

The Effect of Pain Conditioning on Experimentally Evoked Cough: Evidence of Impaired Endogenous Inhibitory Control Mechanisms in Refractory Chronic Cough

(2020) Emma Hilton et al.   EUROPEAN RESPIRATORY JOURNAL

Airway Sensory Nerve Density is Increased in Chronic Cough

(2020) Clare O. Shapiro et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Aprepitant For Cough in Lung Cancer: A Randomised Placebo-Controlled Trial and Mechanistic Insights

(2020) Jaclyn A Smith et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

RFC1 expansions can mimic hereditary sensory neuropathy with cough and Sjögren syndrome

(2020) Kishore R Kumar et al.   BRAIN

Global physiology and pathophysiology of cough: Part 1. Cough phenomenology: CHEST Guideline and Expert Panel report

(2020) Kai K. Lee et al.   CHEST

Behavioral and regional brain responses to inhalation of capsaicin modified by painful conditioning in humans

(2020) Abubakar B. Abubakar et al.   CHEST

Aspiration in lethal drug abuse—a consequence of opioid intoxication

(2020) Johannes Nicolakis et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Evidence for multiple bulbar and higher brain circuits processing sensory inputs from the respiratory system in humans

(2020) Michael J. Farrell et al.   JOURNAL OF PHYSIOLOGY-LONDON

The present and future of cough counting tools

(2020) Jocelin Isabel Hall et al.   Journal of Thoracic Disease

Characterization of Occupational Eosinophilic Bronchitis in a Multicenter Cohort of Subjects with Work-Related Asthma Symptoms

(2020) Marta Wiszniewska et al.   Journal of Allergy and Clinical Immunology-In Practice

Inflammatory Subtypes in Classic Asthma and Cough Variant Asthma

(2020) Jie Gao et al.   Journal of Inflammation Research

Small Airways Dysfunction and Bronchial Hyper-Responsiveness in Cough Variant Asthma

(2020) Jie Gao et al.   International Journal of General Medicine

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: The GOLD Science Committee Report 2019

(2019) Dave Singh et al.   EUROPEAN RESPIRATORY JOURNAL

Cardiovascular autonomic effects of transcutaneous auricular nerve stimulation via the tragus in the rat involve spinal cervical sensory afferent pathways

(2019) K.M. Mahadi et al.   Brain Stimulation

Chronic Cough and Gastroesophageal Reflux in Children

(2019) Anne B. Chang et al.   CHEST

The Effect of Gefapixant, a P2X3 antagonist, on Cough Reflex Sensitivity: A randomised placebo-controlled study

(2019) Alyn H. Morice et al.   EUROPEAN RESPIRATORY JOURNAL

Chronic cough: a disorder of response inhibition?

(2019) Stuart B. Mazzone   EUROPEAN RESPIRATORY JOURNAL

What Is Chronic Cough? Terminology

(2019) Lorcan McGarvey et al.   Journal of Allergy and Clinical Immunology-In Practice

An Update on Speech Pathology Management of Chronic Refractory Cough

(2019) Anne E. Vertigan et al.   Journal of Allergy and Clinical Immunology-In Practice

Why chronic cough in children is different

(2019) Ahmad Kantar et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

ERS guidelines on the diagnosis and treatment of chronic cough in adults and children

(2019) Alyn H. Morice et al.   EUROPEAN RESPIRATORY JOURNAL

Lung health and exposure to air pollution in Malawian children (CAPS): a cross-sectional study

(2019) Sarah Rylance et al.   THORAX

Transcriptional Profiling of Individual Airway Projecting Vagal Sensory Neurons

(2019) Stuart B. Mazzone et al.   MOLECULAR NEUROBIOLOGY

Opposing effects of bronchopulmonary C-fiber subtypes on cough in guinea pigs

(2018) Yang-Ling Chou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Classification of Cough as a Symptom in Adults and Management Algorithms

(2018) Richard S. Irwin et al.   CHEST

Treatment of Interstitial Lung Disease associated cough: CHEST guideline and expert panel report

(2018) Surinder S. Birring et al.   CHEST

Ambient Air Pollution and Chronic Bronchitis in a Cohort of U.S. Women

(2018) Laura G. Hooper et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The heterogeneity of chronic cough: a case for endotypes of cough hypersensitivity

(2018) Stuart B Mazzone et al.   Lancet Respiratory Medicine

Laryngeal Dysfunction in Cough Hypersensitivity Syndrome: A Cross-Sectional Observational Study

(2018) Anne E. Vertigan et al.   Journal of Allergy and Clinical Immunology-In Practice

Reflex regulation of breathing by the paratrigeminal nucleus via multiple bulbar circuits

(2018) Alexandria K. Driessen et al.   Brain Structure & Function

Eosinophils increase airway sensory nerve density in mice and in human asthma

(2018) Matthew G. Drake et al.   Science Translational Medicine

Clinically Diagnosing Pertussis-associated Cough in Adults and Children

(2018) Abigail Moore et al.   CHEST

Traffic-related air pollution induces non-allergic eosinophilic airway inflammation and cough hypersensitivity in guinea-pigs

(2018) Zhangfu Fang et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Translational review: Neuroimmune mechanisms in cough and emerging therapeutic targets

(2018) Alice E. McGovern et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Prevalence of Arnold nerve reflex in subjects with and without chronic cough: Relevance to Cough Hypersensitivity Syndrome

(2018) Peter V. Dicpinigaitis et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Capsaicin-evoked cough responses in asthmatic patients: Evidence for airway neuronal dysfunction

(2017) Imran Satia et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cough and bronchiectasis

(2017) Paul McCallion et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

The interaction between bronchoconstriction and cough in asthma

(2017) Imran Satia et al.   THORAX

Long-term prognosis of chronic cough: a prospective, observational cohort study

(2017) Heikki O. Koskela et al.   BMC Pulmonary Medicine

Time to review the provision of addiction treatment for codeine dependence

(2017) Michelle Foley et al.   BMJ-British Medical Journal

Time to review the provision of addiction treatment for codeine dependence

(2017) Michelle Foley et al.   BMJ-British Medical Journal

A neuroanatomical framework for the central modulation of respiratory sensory processing and cough by the periaqueductal grey

(2017) Alice E. McGovern et al.   Journal of Thoracic Disease

Laryngeal Dysfunction: Assessment and Management for the Clinician

(2016) James H. Hull et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Use of Management Pathways or Algorithms in Children With Chronic Cough

(2016) Anne B. Chang et al.   CHEST

The Effects of Azithromycin in Treatment-Resistant Cough

(2016) David Hodgson et al.   CHEST

Objective Cough Frequency, Airway Inflammation, and Disease Control in Asthma

(2016) Paul A. Marsden et al.   CHEST

Treatment of Unexplained Chronic Cough

(2016) Peter Gibson et al.   CHEST

Pregabalin and Speech Pathology Combination Therapy for Refractory Chronic Cough

(2016) Anne E. Vertigan et al.   CHEST

Chronic Cough Due to Gastroesophageal Reflux in Adults

(2016) Peter J. Kahrilas et al.   CHEST

Long-term follow-up of amitriptyline treatment for idiopathic cough

(2016) Marisa A. Ryan et al.   LARYNGOSCOPE

Respiratory disease and the oesophagus: reflux, reflexes and microaspiration

(2016) Lesley A. Houghton et al.   Nature Reviews Gastroenterology & Hepatology

Vagal Afferent Innervation of the Airways in Health and Disease

(2016) Stuart B. Mazzone et al.   PHYSIOLOGICAL REVIEWS

A child chronic cough-specific quality of life measure: development and validation

(2016) Peter A Newcombe et al.   THORAX

Physiotherapy, and speech and language therapy intervention for patients with refractory chronic cough: a multicentre randomised control trial

(2016) Sarah A F Chamberlain Mitchell et al.   THORAX

Neural correlates of cough hypersensitivity in humans: evidence for central sensitisation and dysfunctional inhibitory control

(2016) Ayaka Ando et al.   THORAX

Defining Chronic Cough: A Systematic Review of the Epidemiological Literature

(2016) Woo-Jung Song et al.   Allergy Asthma & Immunology Research

Dysphagia, dystussia, and aspiration pneumonia in elderly people

(2016) Satoru Ebihara et al.   Journal of Thoracic Disease

Morphologic Characterization of Nerves in Whole-Mount Airway Biopsies

(2015) Peter W. West et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effects of Morphine and Midazolam on Pharyngeal Function, Airway Protection, and Coordination of Breathing and Swallowing in Healthy Adults

(2015) Anna I. Hårdemark Cedborg et al.   ANESTHESIOLOGY

Children With Chronic Cough

(2015) Anne B. Chang et al.   CHEST

Somatic Cough Syndrome (Previously Referred to as Psychogenic Cough) and Tic Cough (Previously Referred to as Habit Cough) in Adults and Children

(2015) Anne E. Vertigan et al.   CHEST

The duration of cough in patients with H1N1 influenza

(2015) Ling Lin et al.   Clinical Respiratory Journal

The global epidemiology of chronic cough in adults: a systematic review and meta-analysis

(2015) Woo-Jung Song et al.   EUROPEAN RESPIRATORY JOURNAL

Distinct Brainstem and Forebrain Circuits Receiving Tracheal Sensory Neuron Inputs Revealed Using a Novel Conditional Anterograde Transsynaptic Viral Tracing System

(2015) A. E. McGovern et al.   JOURNAL OF NEUROSCIENCE

Cough and environmental air pollution in China

(2015) Qingling Zhang et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Cough reflex sensitization from esophagus and nose

(2015) Michal Hennel et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS

(2015) Giuseppe Spaziano et al.   Biomed Research International

EAACI Position Paper on assessment of cough in the workplace

(2014) G. Moscato et al.   ALLERGY

A worldwide survey of chronic cough: a manifestation of enhanced somatosensory response

(2014) A. H. Morice et al.   EUROPEAN RESPIRATORY JOURNAL

Expert opinion on the cough hypersensitivity syndrome in respiratory medicine

(2014) A. H. Morice et al.   EUROPEAN RESPIRATORY JOURNAL

Functionally connected brain regions in the network activated during capsaicin inhalation

(2014) Michael J. Farrell et al.   HUMAN BRAIN MAPPING

Is opiate action in cough due to sedation?

(2014) Rebecca S. Dickinson et al.   Therapeutic Advances in Chronic Disease

Brain Activity Associated with Placebo Suppression of the Urge-to-Cough in Humans

(2013) Jennifer Leech et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Longitudinal Assessment of Acute Cough

(2013) Kai K. Lee et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Response of Chronic Cough to Acid-Suppressive Therapy in Patients With Gastroesophageal Reflux Disease

(2013) Peter J. Kahrilas et al.   CHEST

Pharmacodynamic modeling of cough responses to capsaicin inhalation calls into question the utility of the C5 end point

(2013) Emma C.Y. Hilton et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The role of trigeminal nasal TRPM8-expressing afferent neurons in the antitussive effects of menthol

(2013) J. Plevkova et al.   JOURNAL OF APPLIED PHYSIOLOGY

Nonpharmacological Interventions for Refractory Chronic Cough Patients: Systematic Review

(2013) Sarah Chamberlain et al.   LUNG

Monoamine neurocircuitry in depression and strategies for new treatments

(2013) Michel Hamon et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The difficult-to-treat, therapy-resistant cough: Why are current cough treatments not working and what can we do?

(2013) Lorcan McGarvey   PULMONARY PHARMACOLOGY & THERAPEUTICS

Laryngeal sensory dysfunction in laryngeal hypersensitivity syndrome

(2013) Anne E. Vertigan et al.   RESPIROLOGY

Understanding cough and its management in lung cancer

(2013) Amelie S.M. Harle et al.   Current Opinion in Supportive and Palliative Care

Chronic cough as a neuropathic disorder

(2013) Kian Fan Chung et al.   Lancet Respiratory Medicine

The Effect of Placebo Conditioning on Capsaicin-Evoked Urge to Cough

(2012) Jennifer Leech et al.   CHEST

Chronic Cough

(2012) Samantha Decalmer et al.   CHEST

A Prospective, Multicenter Survey on Causes of Chronic Cough in China

(2012) Kefang Lai et al.   CHEST

Respiratory symptoms in children living near busy roads and their relationship to vehicular traffic: results of an Italian multicenter study (SIDRIA 2)

(2012) Enrica Migliore et al.   Environmental Health

Parent cough-specific quality of life: Development and validation of a short form

(2012) Peter A. Newcombe et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Volitional control of reflex cough

(2012) Karen W. Hegland et al.   JOURNAL OF APPLIED PHYSIOLOGY

Reflux aspiration in children with neurodisability—a significant problem, but can we measure it?

(2012) Ruth Trinick et al.   JOURNAL OF PEDIATRIC SURGERY

Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial

(2012) Nicole M Ryan et al.   LANCET

The long term outcome of patients with unexplained chronic cough

(2012) Nadia Yousaf et al.   RESPIRATORY MEDICINE

Transient receptor potential genes, smoking, occupational exposures and cough in adults

(2012) Lidwien AM Smit et al.   RESPIRATORY RESEARCH

Do Sex and Atopy Influence Cough Outcome Measurements in Children?

(2011) Anne B. Chang et al.   CHEST

Antitussive Effects of Memantine in Guinea Pigs

(2011) Jaclyn A. Smith et al.   CHEST

Investigation of the Neural Control of Cough and Cough Suppression in Humans Using Functional Brain Imaging

(2011) S. B. Mazzone et al.   JOURNAL OF NEUROSCIENCE

Pepsin and bile acids in induced sputum of chronic cough patients

(2011) Marcin Grabowski et al.   RESPIRATORY MEDICINE

Clinical and physiological features of postinfectious chronic cough associated with H1N1 infection

(2011) Nicole M. Ryan et al.   RESPIRATORY MEDICINE

Encoding of the cough reflex in anesthetized guinea pigs

(2010) Brendan J. Canning et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Chronic cough in patients with sleep-disordered breathing

(2010) K. K. Y. Chan et al.   EUROPEAN RESPIRATORY JOURNAL

Symptom variability in patients with severe COPD: a pan-European cross-sectional study

(2010) R. Kessler et al.   EUROPEAN RESPIRATORY JOURNAL

An essential component to brainstem cough gating identified in anesthetized guinea pigs

(2010) Brendan J. Canning et al.   FASEB JOURNAL

Acoustic Cough—Reflux Associations in Chronic Cough: Potential Triggers and Mechanisms

(2010) Jaclyn A. Smith et al.   GASTROENTEROLOGY

Chronic cough and irritable larynx

(2010) Caterina B. Bucca et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Microinjection of codeine into the region of the caudal ventral respiratory column suppresses cough in anesthetized cats

(2010) Ivan Poliacek et al.   JOURNAL OF APPLIED PHYSIOLOGY

A prospective global measure, the Punum Ladder, provides more valid assessments of quality of life than a retrospective transition measure

(2010) Kenneth E. Fletcher et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Chronic Refractory Cough as a Sensory Neuropathy: Evidence From a Reinterpretation of Cough Triggers

(2010) Anne E. Vertigan et al.   JOURNAL OF VOICE

Cough Hypersensitivity Syndrome: A Distinct Clinical Entity

(2010) A. H. Morice et al.   LUNG

Cough in the elderly: A novel strategy for preventing aspiration pneumonia

(2010) Satoru Ebihara et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Air pollution and children's respiratory symptoms in six cities of Northern China

(2010) Guowei Pan et al.   RESPIRATORY MEDICINE

Long-term low-dose erythromycin in patients with unexplained chronic cough: a double-blind placebo controlled trial

(2010) N. Yousaf et al.   THORAX

Measuring cough severity: development and pilot testing of a new seven-item cough severity patient-reported outcome measure

(2010) Margaret Vernon et al.   Therapeutic Advances in Respiratory Disease

Improvements in PM10Exposure and Reduced Rates of Respiratory Symptoms in a Cohort of Swiss Adults (SAPALDIA)

(2009) Christian Schindler et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Diagnosis and Management of Premature Ventricular Complexes-Associated Chronic Cough

(2009) Sebastian M. Stec et al.   CHEST

Selective Expression of a Sodium Pump Isozyme by Cough Receptors and Evidence for Its Essential Role in Regulating Cough

(2009) S. B. Mazzone et al.   JOURNAL OF NEUROSCIENCE

Characterization of laryngeal dysfunction in chronic persistent cough

(2009) Nicole M. Ryan et al.   LARYNGOSCOPE

What Is the Burden of Chronic Cough for Families?

(2008) Julie M. Marchant et al.   CHEST

Cough and Sputum Production Are Associated With Frequent Exacerbations and Hospitalizations in COPD Subjects

(2008) Pierre-Régis Burgel et al.   CHEST

Extended secondhand tobacco smoke exposure induces plasticity in nucleus tractus solitarius second-order lung afferent neurons in young guinea pigs

(2008) Shin-Ichi Sekizawa et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Prevalence, pathogenesis, and causes of chronic cough

(2008) Kian Fan Chung et al.   LANCET

Pharmacological disruption of calcium channel trafficking by the  2  ligand gabapentin

(2008) J. Hendrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of Cough Across Different Chronic Respiratory Diseases

(2007) Liam Polley et al.   CHEST