Efficacy and safety of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials

Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study

(2021) Alyn Morice et al.   EUROPEAN RESPIRATORY JOURNAL

Performance of a digital signal processing algorithm for the accurate quantification of cough frequency

(2021) Jaclyn A. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

Gefapixant, a P2X3 receptor antagonist, for the treatment of refractory or unexplained chronic cough: a randomised, double-blind, controlled, parallel-group, phase 2b trial

(2020) Jaclyn A Smith et al.   Lancet Respiratory Medicine

Evidence for multiple bulbar and higher brain circuits processing sensory inputs from the respiratory system in humans

(2020) Michael J. Farrell et al.   JOURNAL OF PHYSIOLOGY-LONDON

Defining Minimal Clinically Important Differences (MCID) in Chronic Cough: Analyses of Objective Cough Counts from a Phase 2 Randomized Controlled Trial

(2019) Allison M. Nguyen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Effect of Gefapixant, a P2X3 antagonist, on Cough Reflex Sensitivity: A randomised placebo-controlled study

(2019) Alyn H. Morice et al.   EUROPEAN RESPIRATORY JOURNAL

What Is Chronic Cough? Terminology

(2019) Lorcan McGarvey et al.   Journal of Allergy and Clinical Immunology-In Practice

BLU-5937: A selective P2X3 antagonist with potent anti-tussive effect and no taste alteration

(2019) Denis Garceau et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

ERS guidelines on the diagnosis and treatment of chronic cough in adults and children

(2019) Alyn H. Morice et al.   EUROPEAN RESPIRATORY JOURNAL

The Powerful Placebo Effect in Cough: Relevance to Treatment and Clinical Trials

(2019) Ron Eccles   LUNG

Treatment of Unexplained Chronic Cough

(2016) Peter Gibson et al.   CHEST

Chronic Cough

(2016) Jaclyn A. Smith et al.   NEW ENGLAND JOURNAL OF MEDICINE

How best to measure cough clinically

(2015) Surinder S Birring et al.   CURRENT OPINION IN PHARMACOLOGY

The global epidemiology of chronic cough in adults: a systematic review and meta-analysis

(2015) Woo-Jung Song et al.   EUROPEAN RESPIRATORY JOURNAL

P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study

(2015) Rayid Abdulqawi et al.   LANCET

The Impact of Chronic Cough: A Cross-Sectional European Survey

(2015) Sarah A. F. Chamberlain et al.   LUNG

Overview of the Management of Cough

(2014) Richard S. Irwin et al.   CHEST

A worldwide survey of chronic cough: a manifestation of enhanced somatosensory response

(2014) A. H. Morice et al.   EUROPEAN RESPIRATORY JOURNAL

Expert opinion on the cough hypersensitivity syndrome in respiratory medicine

(2014) A. H. Morice et al.   EUROPEAN RESPIRATORY JOURNAL

Nucleotide signalling during inflammation

(2014) Marco Idzko et al.   NATURE

Brain Activity Associated with Placebo Suppression of the Urge-to-Cough in Humans

(2013) Jennifer Leech et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cough frequency in health and disease

(2013) N. Yousaf et al.   EUROPEAN RESPIRATORY JOURNAL

Chronic cough as a neuropathic disorder

(2013) Kian Fan Chung et al.   Lancet Respiratory Medicine

Investigation of the Neural Control of Cough and Cough Suppression in Humans Using Functional Brain Imaging

(2011) S. B. Mazzone et al.   JOURNAL OF NEUROSCIENCE

Unexplained Cough in the Adult

(2010) Richard S. Irwin   OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA

Management of chronic cough

(2008) Ian D Pavord et al.   LANCET