Myelosuppression Alleviation and Hematopoietic Regeneration by Tetrahedral‐Framework Nucleic‐Acid Nanostructures Functionalized with Osteogenic Growth Peptide

Facilitating In Situ Tumor Imaging with a Tetrahedral DNA Framework‐Enhanced Hybridization Chain Reaction Probe

(2022) Bowen Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Biomimetic Nanoerythrosome‐Coated Aptamer–DNA Tetrahedron/Maytansine Conjugates: pH‐Responsive and Targeted Cytotoxicity for HER2‐Positive Breast Cancer

(2022) Wenjuan Ma et al.   ADVANCED MATERIALS

Sugemalimab versus placebo, in combination with platinum-based chemotherapy, as first-line treatment of metastatic non-small-cell lung cancer (GEMSTONE-302): interim and final analyses of a double-blind, randomised, phase 3 clinical trial

(2022) Caicun Zhou et al.   LANCET ONCOLOGY

Tetrahedral Framework Nucleic Acids Can Alleviate Taurocholate-Induced Severe Acute Pancreatitis and Its Subsequent Multiorgan Injury in Mice

(2022) Yun Wang et al.   NANO LETTERS

Platinum-based drugs for cancer therapy and anti-tumor strategies

(2022) Chunyu Zhang et al.   Theranostics

Repair of infected bone defect with Clindamycin-Tetrahedral DNA nanostructure Complex-loaded 3D bioprinted hybrid scaffold

(2022) Jun Li et al.   CHEMICAL ENGINEERING JOURNAL

Mechanisms of Uptake and Membrane Curvature Generation for the Internalization of Silica Nanoparticles by Cells

(2022) Valentina Francia et al.   NANO LETTERS

Approaches and materials for endocytosis-independent intracellular delivery of proteins

(2022) Nanxi Chen et al.   BIOMATERIALS

Traditional Chinese medicine on treating myelosuppression after chemotherapy

(2021) Sihang Yang et al.   MEDICINE

A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis

(2021) Bo Shen et al.   NATURE

C-Kit, a Double-Edged Sword in Liver Regeneration and Diseases

(2021) Weina Wang et al.   Frontiers in Genetics

Rebuilding the hematopoietic stem cell niche: Recent developments and future prospects

(2021) Chandralekha Chatterjee et al.   Acta Biomaterialia

Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells

(2021) Pia Sommerkamp et al.   BLOOD

Biological effects of formation of protein corona onto nanoparticles

(2021) Rakesh Kumar Mishra et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Advanced nanomedicine and cancer: Challenges and opportunities in clinical translation

(2021) Juan Gonzalez-Valdivieso et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The protein corona and its effects on nanoparticle-based drug delivery systems

(2021) Hanmei Li et al.   Acta Biomaterialia

Niches that regulate stem cells and hematopoiesis in adult bone marrow

(2021) Stefano Comazzetto et al.   DEVELOPMENTAL CELL

Hematopoietic Recovery using Multi-Cytokine Therapy in 8 Patients Presenting Radiation-Induced Myelosuppression after Radiological Accidents

(2021) Marc Benderitter et al.   RADIATION RESEARCH

Tetrahedral framework nucleic acids promote the biological functions and related mechanism of synovium-derived mesenchymal stem cells and show improved articular cartilage regeneration activity in situ

(2021) Liwei Fu et al.   Bioactive Materials

Biological Effect of Differently Sized Tetrahedral Framework Nucleic Acids: Endocytosis, Proliferation, Migration, and Biodistribution

(2021) Sirong Shi et al.   ACS Applied Materials & Interfaces

A DNA Nanostructure-Based Neuroprotectant against Neuronal Apoptosis via Inhibiting Toll-like Receptor 2 Signaling Pathway in Acute Ischemic Stroke

(2021) Mi Zhou et al.   ACS Nano

The extracellular matrix of hematopoietic stem cell niches

(2021) Cornelia Lee-Thedieck et al.   ADVANCED DRUG DELIVERY REVIEWS

Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution

(2021) Christina M. Termini et al.   Nature Communications

Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling

(2021) In-Chi Young et al.   Cell Reports

Real-world burden of chemotherapy-induced myelosuppression in patients with small cell lung cancer: a retrospective analysis of electronic medical data from community cancer care providers

(2021) Robert S. Epstein et al.   JOURNAL OF MEDICAL ECONOMICS

Recent Advances in Developmental Hematopoiesis: Diving Deeper With New Technologies

(2021) Bart Weijts et al.   Frontiers in Immunology

Tetrahedral framework nucleic acids-based delivery of microRNA-155 inhibits choroidal neovascularization by regulating the polarization of macrophages

(2021) Xin Qin et al.   Bioactive Materials

Trends in Use of Granulocyte Colony-Stimulating Factor Following Introduction of Biosimilars Among Adults With Cancer and Commercial or Medicare Insurance From 2014 to 2019

(2021) Ching-Yu Wang et al.   JAMA Network Open

Role of growth factors in hematopoietic stem cell niche

(2020) Dabin Lee et al.   CELL BIOLOGY AND TOXICOLOGY

Erythropoietin and its derivatives: from tissue protection to immune regulation

(2020) Bo Peng et al.   Cell Death & Disease

Functional Applications of Nucleic Acid–Protein Hybrid Nanostructures

(2020) Joshua B. McCluskey et al.   TRENDS IN BIOTECHNOLOGY

Patient Burden and Real-World Management of Chemotherapy-Induced Myelosuppression: Results from an Online Survey of Patients with Solid Tumors

(2020) Robert S. Epstein et al.   ADVANCES IN THERAPY

Intravital Imaging Reveals Motility of Adult Hematopoietic Stem Cells in the Bone Marrow Niche

(2020) Samik Upadhaya et al.   Cell Stem Cell

Nucleic acid-based drug delivery strategies

(2020) Xuyu Tan et al.   JOURNAL OF CONTROLLED RELEASE

Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment

(2020) Tao Zhang et al.   Nature Protocols

Induction of blood-circulating bile acids supports recovery from myelosuppressive chemotherapy

(2020) Valgardur Sigurdsson et al.   Blood Advances

Development and characterization of a fully human antibody targeting SCF/c-kit signaling

(2020) Jin-Ock Kim et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Hematopoietic stem and progenitor cell signaling in the niche

(2020) Stephanie N. Hurwitz et al.   LEUKEMIA

Nanoparticles in the Biological Context: Surface Morphology and Protein Corona Formation

(2020) Walter Richtering et al.   Small

G-CSF and G-CSFR Induce a Pro-Tumorigenic Macrophage Phenotype to Promote Colon and Pancreas Tumor Growth

(2020) Ioannis Karagiannidis et al.   Cancers

Restricted Hematopoietic Progenitors and Erythropoiesis Require SCF from Leptin Receptor+ Niche Cells in the Bone Marrow

(2019) Stefano Comazzetto et al.   Cell Stem Cell

Molecular Engineering of Functional Nucleic Acid Nanomaterials toward In Vivo Applications

(2019) JingJing Zhang et al.   Advanced Healthcare Materials

Evaluation of Pharmacodynamic Responses to Cancer Therapeutic Agents Using DNA Damage Markers

(2019) Deborah F. Wilsker et al.   CLINICAL CANCER RESEARCH

Multifaceted roles of thrombopoietin in hematopoietic stem cell regulation

(2019) Ayako Nakamura‐Ishizu et al.   Annals of the New York Academy of Sciences

Functional Nucleic Acids-Nanomaterials: Development, Properties, and Applications

(2019) Wentao Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tailoring the component of protein corona via simple chemistry

(2019) Xiang Lu et al.   Nature Communications

Enhanced Neural Regeneration with a Concomitant Treatment of Framework Nucleic Acid and Stem Cells in Spinal Cord Injury

(2019) Wenjuan Ma et al.   ACS Applied Materials & Interfaces

Bone Marrow Micro-Environment in Normal and Deranged Hematopoiesis: Opportunities for Regenerative Medicine and Therapies

(2018) Shawn M. Sarkaria et al.   BIOESSAYS

DNA Nanotechnology-Enabled Drug Delivery Systems

(2018) Qinqin Hu et al.   CHEMICAL REVIEWS

Framework-Nucleic-Acid-Enabled Biosensor Development

(2018) Fan Yang et al.   ACS Sensors

A Multiplexed Screening Assay to Evaluate Chemotherapy-Induced Myelosuppression Using Healthy Peripheral Blood and Bone Marrow

(2018) Komal K. Javarappa et al.   SLAS Discovery

Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration

(2018) Heather A. Himburg et al.   Cell Stem Cell

Advances in biological applications of self-assembled DNA tetrahedral nanostructures

(2018) Songhang Li et al.   Materials Today

Rationally Designed DNA-Origami Nanomaterials for Drug Delivery In Vivo

(2018) Qiao Jiang et al.   ADVANCED MATERIALS

Cloaking nanoparticles with protein corona shield for targeted drug delivery

(2018) Jun Yong Oh et al.   Nature Communications

Angelica sinensis Polysaccharides Ameliorate Stress-Induced Premature Senescence of Hematopoietic Cell via Protecting Bone Marrow Stromal Cells from Oxidative Injuries Caused by 5-Fluorouracil

(2017) Hanxianzhi Xiao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF

(2017) Bo O. Zhou et al.   NATURE CELL BIOLOGY

SCA-1 Expression Level Identifies Quiescent Hematopoietic Stem and Progenitor Cells

(2017) Mina N.F. Morcos et al.   Stem Cell Reports

The potential of protein–nanomaterial interaction for advanced drug delivery

(2016) Qiang Peng et al.   JOURNAL OF CONTROLLED RELEASE

Preclinical Characterization of G1T28: A Novel CDK4/6 Inhibitor for Reduction of Chemotherapy-Induced Myelosuppression

(2016) J. E. Bisi et al.   MOLECULAR CANCER THERAPEUTICS

The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery

(2016) Claudia Corbo et al.   Nanomedicine

Preformed albumin corona, a protective coating for nanoparticles based drug delivery system

(2013) Qiang Peng et al.   BIOMATERIALS

Regulation of hematopoietic stem cells by bone marrow stromal cells

(2013) Bryan A. Anthony et al.   TRENDS IN IMMUNOLOGY

Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells

(2010) Heather A Himburg et al.   NATURE MEDICINE