A DNA Nanostructure-Based Neuroprotectant against Neuronal Apoptosis via Inhibiting Toll-like Receptor 2 Signaling Pathway in Acute Ischemic Stroke

Treating LRRK2‐Related Parkinson's Disease by Inhibiting the mTOR Signaling Pathway to Restore Autophagy

(2021) Weitong Cui et al.   ADVANCED FUNCTIONAL MATERIALS

The Neuroprotective Effect of MicroRNA‐22‐3p Modified Tetrahedral Framework Nucleic Acids on Damaged Retinal Neurons Via TrkB/BDNF Signaling Pathway

(2021) Jiajie Li et al.   ADVANCED FUNCTIONAL MATERIALS

Therapeutic siCCR2 Loaded by Tetrahedral Framework DNA Nanorobotics in Therapy for Intracranial Hemorrhage

(2021) Wei Fu et al.   ADVANCED FUNCTIONAL MATERIALS

Functionalizing Framework Nucleic‐Acid‐Based Nanostructures for Biomedical Application

(2021) Tao Zhang et al.   ADVANCED MATERIALS

Effect of tetrahedral DNA nanostructures on LPS‐induced neuroinflammation in mice

(2021) Xiao Yang et al.   CHINESE CHEMICAL LETTERS

Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin

(2020) Debia Wakhloo et al.   Nature Communications

Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment

(2020) Tao Zhang et al.   Nature Protocols

Acute Ischemic Stroke

(2020) William J. Powers   NEW ENGLAND JOURNAL OF MEDICINE

Therapeutic targets of oxidative/nitrosative stress and neuroinflammation in ischemic stroke: Applications for natural product efficacy with omics and systemic biology

(2020) Hansen Chen et al.   PHARMACOLOGICAL RESEARCH

Tetrahedral framework nucleic acids act as antioxidants in acute kidney injury treatment

(2020) Qi Zhang et al.   CHEMICAL ENGINEERING JOURNAL

The protective effect of tetrahedral framework nucleic acids on periodontium under inflammatory conditions

(2020) Mi Zhou et al.   Bioactive Materials

Developmental differences in microglia morphology and gene expression during normal brain development and in response to hypoxia-ischemia

(2019) Pelin Cengiz et al.   NEUROCHEMISTRY INTERNATIONAL

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

(2019) Emelia J. Benjamin et al.   CIRCULATION

Global brain inflammation in stroke

(2019) Kaibin Shi et al.   LANCET NEUROLOGY

Neuroprotective and Neurotherapeutic Effects of Tetrahedral Framework Nucleic Acids on Parkinson’s Disease in Vitro

(2019) Weitong Cui et al.   ACS Applied Materials & Interfaces

Enhanced Neural Regeneration with a Concomitant Treatment of Framework Nucleic Acid and Stem Cells in Spinal Cord Injury

(2019) Wenjuan Ma et al.   ACS Applied Materials & Interfaces

Self-Assembled Tetrahedral DNA Nanostructures Promote Neural Stem Cell Proliferation and Neuronal Differentiation

(2018) Wenjuan Ma et al.   ACS Applied Materials & Interfaces

Neuroprotective Effect of Tetrahedral DNA Nanostructures in a Cell Model of Alzheimer’s Disease

(2018) Xiaoru Shao et al.   ACS Applied Materials & Interfaces

Impact of aging, Alzheimer's disease and Parkinson's disease on the blood-brain barrier transport of therapeutics

(2018) Yijun Pan et al.   ADVANCED DRUG DELIVERY REVIEWS

Protective effect and mechanism of ginsenoside Rg1 in cerebral ischaemia-reperfusion injury in mice

(2018) Le Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

(2018) Gregory W. Albers et al.   NEW ENGLAND JOURNAL OF MEDICINE

Global Burden of Stroke

(2018) Mira Katan et al.   SEMINARS IN NEUROLOGY

Synthetic α5β1 integrin ligand PHSRN is proangiogenic and neuroprotective in cerebral ischemic stroke

(2018) Cheng-Chun Wu et al.   BIOMATERIALS

Tetrahedral DNA nanostructures facilitate neural stem cell migration via activating RHOA/ROCK2 signalling pathway

(2018) Wenjuan Ma et al.   CELL PROLIFERATION

The regulatory role of Toll-like receptors after ischemic stroke: neurosteroids as TLR modulators with the focus on TLR2/4

(2018) Saeedeh Tajalli-Nezhad et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Staining of HLA-DR, Iba1 and CD68 in human microglia reveals partially overlapping expression depending on cellular morphology and pathology

(2017) Debbie A.E. Hendrickx et al.   JOURNAL OF NEUROIMMUNOLOGY

Pre-ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting endoplasmic reticulum stress-dependent autophagy via PERK and IRE1 signalings

(2017) Dayun Feng et al.   JOURNAL OF PINEAL RESEARCH

Stroke

(2017) Graeme J Hankey   LANCET

High-mobility group box-1 as an autocrine trophic factor in white matter stroke

(2017) Jun Young Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The erythropoietin-derived peptide MK-X and erythropoietin have neuroprotective effects against ischemic brain damage

(2017) Seung-Jun Yoo et al.   Cell Death & Disease

Colony stimulating factor 1 receptor inhibition eliminates microglia and attenuates brain injury after intracerebral hemorrhage

(2016) Minshu Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dynamic change of neutrophil to lymphocyte ratio and hemorrhagic transformation after thrombolysis in stroke

(2016) Zhiliang Guo et al.   Journal of Neuroinflammation

Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

(2016) Mayank Goyal et al.   LANCET

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

(2016) Ángel Chamorro et al.   LANCET NEUROLOGY

Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

(2016) Yejie Shi et al.   Nature Communications

Role of adaptor protein MyD88 in TLR-mediated preconditioning and neuroprotection after acute excitotoxicity

(2015) Antoine Larochelle et al.   BRAIN BEHAVIOR AND IMMUNITY

Intravenous immunoglobulin (IVIg) dampens neuronal toll-like receptor-mediated responses in ischemia

(2015) Ker Zhing Lok et al.   Journal of Neuroinflammation

Designing DNA nanodevices for compatibility with the immune system of higher organisms

(2015) Sunaina Surana et al.   Nature Nanotechnology

Neurogenesis is enhanced by stroke in multiple new stem cell niches along the ventricular system at sites of high BBB permeability

(2015) Ruihe Lin et al.   NEUROBIOLOGY OF DISEASE

The Blood–Brain Barrier

(2015) Richard Daneman et al.   Cold Spring Harbor Perspectives in Biology

Single-Particle Tracking and Modulation of Cell Entry Pathways of a Tetrahedral DNA Nanostructure in Live Cells

(2014) Le Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanotheragnostic Applications for Ischemic and Hemorrhagic Strokes: Improved Delivery for a Better Prognosis

(2014) Tarek H. Mouhieddine et al.   Current Neurology and Neuroscience Reports

Effects of size and surface of zinc oxide and aluminum-doped zinc oxide nanoparticles on cell viability inferred by proteomic analyses

(2014) Hsiao-Chi Chuang et al.   International Journal of Nanomedicine

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

(2014) Jonathan Emberson et al.   LANCET

The significance of matrix metalloproteinase (MMP)-2 and MMP-9 in the ischemic stroke

(2013) Jacek Kurzepa et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010

(2013) Valery L Feigin et al.   LANCET

HIF-1  is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2 -induced excessive erythropoiesis

(2012) K. Franke et al.   BLOOD

Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain

(2012) Takashi Shichita et al.   NATURE MEDICINE

Toxicity of nanomaterials

(2011) Shahriar Sharifi et al.   CHEMICAL SOCIETY REVIEWS

Gene delivery targeted to the brain using an Angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer

(2009) Weilun Ke et al.   BIOMATERIALS

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

(2009) Mathias Gelderblom et al.   STROKE

Pharmacokinetics and Biodistribution of Nanoparticles

(2008) Shyh-Dar Li et al.   MOLECULAR PHARMACEUTICS

Methodological Quality of Animal Studies of Neuroprotective Agents Currently in Phase II/III Acute Ischemic Stroke Trials

(2008) Maria Philip et al.   STROKE

Experimental models, neurovascular mechanisms and translational issues in stroke research

(2007) E H Lo   BRITISH JOURNAL OF PHARMACOLOGY