Biomimetic Nanoerythrosome‐Coated Aptamer–DNA Tetrahedron/Maytansine Conjugates: pH‐Responsive and Targeted Cytotoxicity for HER2‐Positive Breast Cancer

Tetrahedral Framework Nucleic Acid-Based Delivery of Resveratrol Alleviates Insulin Resistance: From Innate to Adaptive Immunity

(2021) Yanjing Li et al.   Nano-Micro Letters

Tetrahedral Framework Nucleic Acids Induce Immune Tolerance and Prevent the Onset of Type 1 Diabetes

(2021) Shaojingya Gao et al.   NANO LETTERS

Targeting the autophagy promoted antitumor effect of T-DM1 on HER2-positive gastric cancer

(2021) Jinghui Zhang et al.   Cell Death & Disease

Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect

(2021) Jianhong Yang et al.   Science Advances

Enhanced Penetrability of a Tetrahedral Framework Nucleic Acid by Modification with iRGD for DOX-Targeted Delivery to Triple-Negative Breast Cancer

(2021) Mengting Liu et al.   ACS Applied Materials & Interfaces

A Review on Phytochemicals of the Genus Maytenus and Their Bioactive Studies

(2021) Yuan-Yuan Huang et al.   MOLECULES

An intelligent cell-selective polymersome-DM1 nanotoxin toward triple negative breast cancer

(2021) Yifan Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Bioswitchable Delivery of microRNA by Framework Nucleic Acids: Application to Bone Regeneration

(2021) Songhang Li et al.   Small

Nanoparticles Encapsulating Nitrosylated Maytansine To Enhance Radiation Therapy

(2020) Shi Gao et al.   ACS Nano

Coating and Stabilization of Liposomes by Clathrin-Inspired DNA Self-Assembly

(2020) Kevin N. Baumann et al.   ACS Nano

Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo

(2020) Lu Zhang et al.   Nature Nanotechnology

Hybrid cell membrane-coated nanoparticles: a multifunctional biomimetic platform for cancer diagnosis and therapy

(2020) Hong-Ying Chen et al.   Acta Biomaterialia

Construction of Bispecific Aptamer–Drug Conjugate by a Hybrid Chemical and Biological Approach

(2020) Yang Sun et al.   BIOCONJUGATE CHEMISTRY

Aptamer Enables Consistent Maytansine Delivery Through Maintaining Receptor Homeostasis for HER2 Targeted Cancer Therapy

(2020) Yan Tan et al.   BIOCONJUGATE CHEMISTRY

Cationic Liposome/DNA Complexes Mediate Antitumor Immunotherapy by Promoting Immunogenic Tumor Cell Death and Dendritic Cell Activation

(2020) Xiuxiu Cong et al.   ACS Applied Materials & Interfaces

DNA Functional Materials Assembled from Branched DNA: Design, Synthesis, and Applications

(2020) Yuhang Dong et al.   CHEMICAL REVIEWS

Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment

(2020) Tao Zhang et al.   Nature Protocols

Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells

(2020) Demet Candas-Green et al.   Nature Communications

PEGylated Protamine-Based Adsorbing Improves the Biological Properties and Stability of Tetrahedral Framework Nucleic Acids

(2019) Yichen Ge et al.   ACS Applied Materials & Interfaces

Engineering Biomimetic Platesomes for pH‐Responsive Drug Delivery and Enhanced Antitumor Activity

(2019) Guangna Liu et al.   ADVANCED MATERIALS

An Intelligent DNA Nanorobot with in Vitro Enhanced Protein Lysosomal Degradation of HER2

(2019) Wenjuan Ma et al.   NANO LETTERS

Antibody–drug conjugates for cancer

(2019) Cindy H Chau et al.   LANCET

G-Quadruplex-Forming Aptamers—Characteristics, Applications, and Perspectives

(2019) Carolina Roxo et al.   MOLECULES

Red blood cell–derived nanoerythrosome for antigen delivery with enhanced cancer immunotherapy

(2019) Xiao Han et al.   Science Advances

Aptamers Chemistry: Chemical Modifications and Conjugation Strategies

(2019) Fadwa Odeh et al.   MOLECULES

Cell Membrane Coating Nanotechnology

(2018) Ronnie H. Fang et al.   ADVANCED MATERIALS

Natural killer cell membrane infused biomimetic liposomes for targeted tumor therapy

(2018) Arunkumar Pitchaimani et al.   BIOMATERIALS

Effects of tetrahedral DNA nanostructures on autophagy in chondrocytes

(2018) Sirong Shi et al.   CHEMICAL COMMUNICATIONS

A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin

(2018) Grégory Menchon et al.   Nature Communications

Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2 + Breast Cancer

(2018) Xiaolin Yu et al.   Molecular Therapy-Nucleic Acids

Aptamer-based targeted therapy

(2018) Guizhi Zhu et al.   ADVANCED DRUG DELIVERY REVIEWS

A basic insight into aptamer-drug conjugates (ApDCs)

(2018) Wenjing Xuan et al.   BIOMATERIALS

Overcoming drug-resistant lung cancer by paclitaxel loaded tetrahedral DNA nanostructures

(2018) X. Xie et al.   Nanoscale

Aptamer-targeted DNA nanostructures with doxorubicin to treat protein tyrosine kinase 7-positive tumours

(2018) Mengting Liu et al.   CELL PROLIFERATION

CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development

(2018) Emily K. Lehrman et al.   NEURON

Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer

(2018) Gunter von Minckwitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

HER2-positive breast cancer

(2017) Sibylle Loibl et al.   LANCET

Synthesis of an ethyleneimine/tetrahedral DNA nanostructure complex and its potential application as a multi-functional delivery vehicle

(2017) Taoran Tian et al.   Nanoscale

Mechanism of microtubule stabilization by taccalonolide AJ

(2017) Yuxi Wang et al.   Nature Communications

Overcoming Tamoxifen Resistance of Human Breast Cancer by Targeted Gene Silencing Using Multifunctional pRNA Nanoparticles

(2016) Yijuan Zhang et al.   ACS Nano

A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy

(2016) John Y. Li et al.   CANCER CELL

Oligonucleotide aptamer-drug conjugates for targeted therapy of acute myeloid leukemia

(2015) Nianxi Zhao et al.   BIOMATERIALS

An AS1411 aptamer-conjugated liposomal system containing a bubble-generating agent for tumor-specific chemotherapy that overcomes multidrug resistance

(2015) Zi-Xian Liao et al.   JOURNAL OF CONTROLLED RELEASE

Receptor Crosslinking: A General Method to Trigger Internalization and Lysosomal Targeting of Therapeutic Receptor:Ligand Complexes

(2015) Paul R Moody et al.   MOLECULAR THERAPY

Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

(2014) Ronnie H. Fang et al.   NANO LETTERS

Efficacy of trastuzumab in Japanese patients with HER2-positive advanced gastric or gastroesophageal junction cancer: a subgroup analysis of the Trastuzumab for Gastric Cancer (ToGA) study

(2011) Akira Sawaki et al.   Gastric Cancer

A New Paradigm for Aptamer Therapeutic AS1411 Action: Uptake by Macropinocytosis and Its Stimulation by a Nucleolin-Dependent Mechanism

(2010) E. M. Reyes-Reyes et al.   CANCER RESEARCH

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

(2010) Yung-Jue Bang et al.   LANCET

Maytansinoid-Antibody Conjugates Induce Mitotic Arrest by Suppressing Microtubule Dynamic Instability

(2010) E. Oroudjev et al.   MOLECULAR CANCER THERAPEUTICS

Self-assembly of a nanoscale DNA box with a controllable lid

(2009) Ebbe S. Andersen et al.   NATURE

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody-Cytotoxic Drug Conjugate

(2008) G. D. Lewis Phillips et al.   CANCER RESEARCH

Assembling Materials with DNA as the Guide

(2008) F. A. Aldaye et al.   SCIENCE