Mutation of foxl1 Results in Reduced Cartilage Markers in a Zebrafish Model of Otosclerosis

Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation

(2021) Pengfei Xu et al.   eLife

The Axenfeld–Rieger Syndrome Gene FOXC1 Contributes to Left–Right Patterning

(2021) Paul W. Chrystal et al.   Genes

Genotype to Phenotype: CRISPR Gene Editing Reveals Genetic Compensation as a Mechanism for Phenotypic Disjunction of Morphants and Mutants

(2021) Cristy M. Salanga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanistic Insights into Axenfeld–Rieger Syndrome from Zebrafish foxc1 and pitx2 Mutants

(2021) Curtis R. French   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations

(2021) Shuyan Dai et al.   NUCLEIC ACIDS RESEARCH

A novel variant in FOXC1 associated with atypical Axenfeld-Rieger syndrome

(2021) Rui Wang et al.   BMC Medical Genomics

A pathogenic deletion in Forkhead Box L1 (FOXL1) identifies the first otosclerosis (OTSC) gene

(2021) Nelly Abdelfatah et al.   HUMAN GENETICS

The development, patterning and evolution of neural crest cell differentiation into cartilage and bone

(2020) Soma Dash et al.   BONE

Uncovering the Secreted Signals and Transcription Factors Regulating the Development of Mammalian Middle Ear Ossicles

(2020) Harinarayana Ankamreddy et al.   DEVELOPMENTAL DYNAMICS

Zebrafish Models of Craniofacial Malformations: Interactions of Environmental Factors

(2020) S. T. Raterman et al.   Frontiers in Cell and Developmental Biology

Zebrafish as an Emerging Model for Osteoporosis: A Primary Testing Platform for Screening New Osteo-Active Compounds

(2019) Dylan J. M. Bergen et al.   Frontiers in Endocrinology

Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the retinal ganglion cell layer

(2019) Jurgienne Umali et al.   VISION RESEARCH

Using zebrafish to study skeletal genomics

(2019) Ronald Y. Kwon et al.   BONE

Genetic compensation triggered by mutant mRNA degradation

(2019) Mohamed A. El-Brolosy et al.   NATURE

foxc1 is required for embryonic head vascular smooth muscle differentiation in zebrafish

(2019) Thomas R. Whitesell et al.   DEVELOPMENTAL BIOLOGY

Dual role of Jam3b in early hematopoietic and vascular development

(2019) Isao Kobayashi et al.   DEVELOPMENT

A highlight on Sonic hedgehog pathway

(2018) Gabriela Basile Carballo et al.   Cell Communication and Signaling

Axenfeld-Rieger syndrome

(2018) M. Seifi et al.   CLINICAL GENETICS

Fox proteins are modular competency factors for facial cartilage and tooth specification

(2018) Pengfei Xu et al.   DEVELOPMENT

Zebrafish as a model to study bone maturation: Nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column

(2018) Zhuo Chang et al.   Journal of the Mechanical Behavior of Biomedical Materials

Genetic compensation: A phenomenon in search of mechanisms

(2017) Mohamed A. El-Brolosy et al.   PLoS Genetics

Relation of otosclerosis and osteoporosis: A bone mineral density study

(2016) Doğan Atan et al.   AURIS NASUS LARYNX

Bone Health in Patients With Hematopoietic Disorders of Bone Marrow Origin: Systematic Review and Meta- Analysis

(2016) Kieran Steer et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone development

(2015) Agnes D. Berendsen et al.   BONE

A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation

(2015) E. Kozhemyakina et al.   DEVELOPMENT

Building the backbone: the development and evolution of vertebral patterning

(2015) A. Fleming et al.   DEVELOPMENT

Distinct effects of Hoxa2 overexpression in cranial neural crest populations reveal that the mammalian hyomandibular-ceratohyal boundary maps within the styloid process

(2015) Taro Kitazawa et al.   DEVELOPMENTAL BIOLOGY

Foxc2 regulates osteogenesis and angiogenesis of bone marrow mesenchymal stem cells

(2013) Wulin You et al.   BMC MUSCULOSKELETAL DISORDERS

Foxc1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx2

(2013) J. Sun et al.   DEVELOPMENT

Development of the Endochondral Skeleton

(2013) F. Long et al.   Cold Spring Harbor Perspectives in Biology

Attenuated BMP1 Function Compromises Osteogenesis, Leading to Bone Fragility in Humans and Zebrafish

(2012) P.V. Asharani et al.   AMERICAN JOURNAL OF HUMAN GENETICS

COL1A1 association and otosclerosis: A meta-analysis

(2012) Isabelle Schrauwen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Evolution of the mammalian middle ear and jaw: adaptations and novel structures

(2012) Neal Anthwal et al.   JOURNAL OF ANATOMY

Novel genetic loci associated with osteoporosis

(2010) Annie W.C. Kung   BONE

History of studies on mammalian middle ear evolution: A comparative morphological and developmental biology perspective

(2010) Masaki Takechi et al.   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

The forkhead transcription factor Foxc2 stimulates osteoblast differentiation

(2009) Se Hwa Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A gain of function mutation causing skeletal overgrowth in the rapunzel mutant

(2009) Julie Green et al.   DEVELOPMENTAL BIOLOGY

Axenfeld–Rieger syndrome and spectrum of PITX2 and FOXC1 mutations

(2009) Zeynep Tümer et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA

(2009) T. Sekiya et al.   GENES & DEVELOPMENT

Transcriptional regulation of WNT2B based on the balance of Hedgehog, Notch, BMP and WNT signals

(2009) Katoh   INTERNATIONAL JOURNAL OF ONCOLOGY

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

(2009) Fernando Rivadeneira et al.   NATURE GENETICS

The evolution of Fox genes and their role in development and disease

(2009) Sridhar Hannenhalli et al.   NATURE REVIEWS GENETICS

RNA Isolation from Embryonic Zebrafish and cDNA Synthesis for Gene Expression Analysis

(2009) Samuel M. Peterson et al.   Jove-Journal of Visualized Experiments

An overview of the etiology of otosclerosis

(2008) Konstantinos Markou et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

FoxF1 and FoxL1 Link Hedgehog Signaling and the Control of Epithelial Proliferation in the Developing Stomach and Intestine

(2008) Blair B. Madison et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols