Rapidly Increasing Serum 25(OH)D Boosts the Immune System, against Infections—Sepsis and COVID-19

COVID-19 and vitamin D (Co-VIVID study): a systematic review and meta-analysis of randomized controlled trials

(2022) Seshadri Reddy Varikasuvu et al.   Expert Review of Anti-Infective Therapy

Pre-infection 25-hydroxyvitamin D3 levels and association with severity of COVID-19 illness

(2022) Amiel A. Dror et al.   PLoS One

Vitamin D regulation of immune function during covid-19

(2022) Daniel D. Bikle   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Association of vitamin D status with COVID-19 and its severity

(2022) Jae Hyun Bae et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Physiological levels of 25‐hydroxyvitamin D 3 induce a suppressive CD4 + T cell phenotype not reflected in the epigenetic landscape

(2022) Carina Matos et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

A Narrative Review of the Evidence for Variations in Serum 25-Hydroxyvitamin D Concentration Thresholds for Optimal Health

(2022) William B. Grant et al.   Nutrients

Populations in Low-Magnesium Areas Were Associated with Higher Risk of Infection in COVID-19’s Early Transmission: A Nationwide Retrospective Cohort Study in the United States

(2022) Jing Tian et al.   Nutrients

The Effect of Circulating Zinc, Selenium, Copper and Vitamin K1 on COVID-19 Outcomes: A Mendelian Randomization Study

(2022) Maria K. Sobczyk et al.   Nutrients

The Impact of Vitamin D Status on COVID-19 Severity among Hospitalized Patients in the Western Region of Saudi Arabia: A Retrospective Cross-Sectional Study

(2022) Taqwa Bushnaq et al.   International Journal of Environmental Research and Public Health

The Role of Vitamin D in COVID-19 and the Impact of Pandemic Restrictions on Vitamin D Blood Content

(2022) Agata Tomaszewska et al.   Frontiers in Pharmacology

Serum Vitamin D Levels Are Associated With Increased COVID-19 Severity and Mortality Independent of Whole-Body and Visceral Adiposity

(2022) Pablo Esteban Vanegas-Cedillo et al.   Frontiers in Nutrition

Vitamin D and its possible relationship to neuroprotection in COVID-19: evidence in the literature

(2022) Saray Quintero-Fabián et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs

(2022) Stephanie Seneff et al.   FOOD AND CHEMICAL TOXICOLOGY

Rapid Nontranscriptional Effects of Calcifediol and Calcitriol

(2022) Simone Donati et al.   Nutrients

Safety Data in Patients with Autoimmune Diseases during Treatment with High Doses of Vitamin D3 According to the “Coimbra Protocol”

(2022) Ulrich Amon et al.   Nutrients

Therapeutic Vitamin D Supplementation Following COVID-19 Diagnosis: Where Do We Stand?—A Systematic Review

(2022) Angelina Bania et al.   Journal of Personalized Medicine

Vitamin D and SARS-CoV2 infection, severity and mortality: A systematic review and meta-analysis

(2022) Oriana D’Ecclesiis et al.   PLoS One

The effect of vitamin D supplementation on clinical symptoms and metabolic profiles in patients with endometriosis

(2021) Abolfazl Mehdizadehkashi et al.   GYNECOLOGICAL ENDOCRINOLOGY

Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19

(2021) Igor H. Murai et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A notable key for estimating the severity of COVID-19: 25-hydroxyvitamin D status

(2021) Merve Ergin Tuncay et al.   Turkish Journal of Biochemistry-Turk Biyokimya Dergisi

Correlation between serum 25‑(OH)D3 level and immune imbalance of Th1/Th2 cytokines in patients with Hashimoto's thyroiditis and its effect on autophagy of human Hashimoto thyroid cells

(2021) Jing He et al.   Experimental and Therapeutic Medicine

Association of Vitamin D Status with SARS-CoV-2 Infection or COVID-19 Severity: A Systematic Review and Meta-analysis

(2021) Asma Kazemi et al.   Advances in Nutrition

COVID-19 Disease Severity and Death in Relation to Vitamin D Status among SARS-CoV-2-Positive UAE Residents

(2021) Habiba AlSafar et al.   Nutrients

Structural and functional insights on vitamin D receptor and CYP24A1 deleterious single nucleotide polymorphisms: A computational and pharmacogenomics perpetual approach

(2021) John Marshal Jayaraj et al.   CELL BIOCHEMISTRY AND FUNCTION

Calcifediol Treatment and COVID-19–Related Outcomes

(2021) Xavier Nogues et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ethnicity as a risk factor for vitamin D deficiency and undesirable COVID‐19 outcomes

(2021) Amir Reza Akbari et al.   REVIEWS IN MEDICAL VIROLOGY

Calcifediol Treatment and Hospital Mortality Due to COVID-19: A Cohort Study

(2021) Juan F. Alcala-Diaz et al.   Nutrients

Role of vitamins and minerals as immunity boosters in COVID-19

(2021) Puneet Kumar et al.   INFLAMMOPHARMACOLOGY

Low Levels of Few Micronutrients May Impact COVID-19 Disease Progression: An Observational Study on the First Wave

(2021) Teresa-Maria Tomasa-Irriguible et al.   Metabolites

Vitamin D biomarkers for Dietary Reference Intake development in children: a systematic review and meta-analysis

(2021) Kevin D Cashman et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

COVID-19 Vaccination Effectiveness Against Infection or Death in a National U.S. Health Care System

(2021) George N. Ioannou et al.   ANNALS OF INTERNAL MEDICINE

Individual participant data (IPD)-level meta-analysis of randomised controlled trials to estimate the vitamin D dietary requirements in dark-skinned individuals resident at high latitude

(2021) Kevin D. Cashman et al.   EUROPEAN JOURNAL OF NUTRITION

Sun exposure as a strategy for acquiring vitamin D in developing countries of tropical region: Challenges & way forward

(2021) Bharati Kulkarni et al.   INDIAN JOURNAL OF MEDICAL RESEARCH

The effects of 1,25( OH ) 2 D 3 treatment on immune responses and intracellular metabolic pathways of bone marrow‐derived dendritic cells from lean and obese mice

(2021) Da Hye Cho et al.   IUBMB LIFE

Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells

(2021) Daniel Chauss et al.   NATURE IMMUNOLOGY

A critical update on the role of mild and serious vitamin D deficiency prevalence and the COVID-19 epidemic in Europe

(2021) Dimitra Rafailia Bakaloudi et al.   NUTRITION

COVID-19 Mortality Risk Correlates Inversely with Vitamin D3 Status, and a Mortality Rate Close to Zero Could Theoretically Be Achieved at 50 ng/mL 25(OH)D3: Results of a Systematic Review and Meta-Analysis

(2021) Lorenz Borsche et al.   Nutrients

The effect of vitamin D supplementation on tobacco-related disorders in individuals with a tobacco use disorder: a randomized clinical trial

(2021) Soheil Bagheri et al.   JOURNAL OF ADDICTIVE DISEASES

Editorial: low population mortality from COVID-19 in countries south of latitude 35 degrees North-supports vitamin D as a factor determining severity. Authors' reply

(2020) Mayur Garg et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Vitamin D can prevent COVID-19 infection-induced multiple organ damage

(2020) Hatice Aygun   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Nutrition, IBD and Gut Microbiota: A Review

(2020) Maria Chiara Mentella et al.   Nutrients

25-Hydroxyvitamin D Concentrations Are Lower in Patients with Positive PCR for SARS-CoV-2

(2020) Antonio D’Avolio et al.   Nutrients

Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths

(2020) William B. Grant et al.   Nutrients

Potential Role of Vitamin D in the Elderly to Resist COVID-19 and to Slow Progression of Parkinson’s Disease

(2020) Casey A. Hribar et al.   Brain Sciences

Perspective: Vitamin D deficiency and COVID‐19 severity – plausibly linked by latitude, ethnicity, impacts on cytokines, ACE2 and thrombosis

(2020) J. M. Rhodes et al.   JOURNAL OF INTERNAL MEDICINE

Differential immunomodulatory effect of vitamin D (1,25 (OH)2 D3) on the innate immune response in different types of cells infected in vitro with infectious bursal disease virus

(2020) J. Jaime et al.   POULTRY SCIENCE

Early Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19

(2020) Jan Alexander et al.   Nutrients

Intratrial Exposure to Vitamin D and New-Onset Diabetes Among Adults With Prediabetes: A Secondary Analysis From the Vitamin D and Type 2 Diabetes (D2d) Study

(2020) Bess Dawson-Hughes et al.   DIABETES CARE

Vitamin D can be effective on the prevention of COVID-19 complications: A narrative review on molecular aspects

(2020) Amir-Abbas Shiravi et al.   INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH

Vitamin D and Wellbeing beyond Infections: COVID-19 and Future Pandemics

(2020) Sidney J. Stohs et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

SARS-CoV-2 positivity rates associated with circulating 25-hydroxyvitamin D levels

(2020) Harvey W. Kaufman et al.   PLoS One

Vitamin D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with COVID-19 infection

(2020) Zhila Maghbooli et al.   PLoS One

High-Dose Vitamin D Supplementation Improves Microcirculation and Reduces Inflammation in Diabetic Neuropathy Patients

(2020) Tatiana Karonova et al.   Nutrients

Why do so many trials of vitamin D supplementation fail?

(2020) Barbara J Boucher   Endocrine Connections

Total, Bioavailable, and Free 25(OH)D Relationship with Indices of Bone Health in Elderly: A Randomized Controlled Trial

(2020) Malak El Sabeh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Putative roles of vitamin D in modulating immune response and immunopathology associated with COVID-19

(2020) Raman Kumar et al.   VIRUS RESEARCH

A Network-Based Analysis Reveals the Mechanism Underlying Vitamin D in Suppressing Cytokine Storm and Virus in SARS-CoV-2 Infection

(2020) Firoz Ahmed   Frontiers in Immunology

Vitamin D and COVID-19: evidence and recommendations for supplementation

(2020) George Griffin et al.   Royal Society Open Science

Daily oral dosing of vitamin D3 using 5000 TO 50,000 international units a day in long-term hospitalized patients: Insights from a seven year experience

(2019) Patrick J. McCullough et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Obesity Decreases Hepatic 25-Hydroxylase Activity Causing Low Serum 25-Hydroxyvitamin D

(2019) Jeffrey D Roizen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Fasting-Induced Transcription Factors Repress Vitamin D Bioactivation, a Mechanism for Vitamin D Deficiency in Diabetes

(2019) Sanna-Mari Aatsinki et al.   DIABETES

Increased vitamin D receptor expression from macrophages after stimulation with M. tuberculosis among persons who have recovered from extrapulmonary tuberculosis

(2019) Christina T. Fiske et al.   BMC INFECTIOUS DISEASES

Vitamin D Binding Protein, Total and Free Vitamin D Levels in Different Physiological and Pathophysiological Conditions

(2019) Daniel David Bikle et al.   Frontiers in Endocrinology

Vitamin D Supplementation for Premenstrual Syndrome-Related inflammation and antioxidant markers in students with vitamin D deficient: a randomized clinical trial

(2019) Hajar Heidari et al.   Scientific Reports

Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients

(2019)   NEW ENGLAND JOURNAL OF MEDICINE

Baseline Characteristics of the Vitamin D and Type 2 Diabetes (D2d) Study: A Contemporary Prediabetes Cohort That Will Inform Diabetes Prevention Efforts

(2018) Erin S. LeBlanc et al.   DIABETES CARE

Determination of free 25(OH)D concentrations and their relationships to total 25(OH)D in multiple clinical populations

(2018) Janice B Schwartz et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Vitamin D and cardiovascular diseases: Causality

(2018) Sunil J. Wimalawansa   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Vitamin D supplementation guidelines

(2018) Pawel Pludowski et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Non-musculoskeletal benefits of vitamin D

(2018) Sunil J. Wimalawansa   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Is calcifediol better than cholecalciferol for vitamin D supplementation?

(2018) J. M. Quesada-Gomez et al.   OSTEOPOROSIS INTERNATIONAL

Breast cancer risk markedly lower with serum 25-hydroxyvitamin D concentrations ≥60 vs

(2018) Sharon L. McDonnell et al.   PLoS One

ESPEN guideline on clinical nutrition in the intensive care unit

(2018) Pierre Singer et al.   CLINICAL NUTRITION

CYP24A1 Inhibition Facilitates the Antiproliferative Effect of 1,25(OH)2D3 Through Downregulation of the WNT/β-Catenin Pathway and Methylation-Mediated Regulation of CYP24A1 in Colorectal Cancer Cells

(2018) Hongyan Sun et al.   DNA AND CELL BIOLOGY

Magnesium status and supplementation influence vitamin D status and metabolism: results from a randomized trial

(2018) Qi Dai et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Vitamin D metabolites in captivity? Should we measure free or total 25(OH)D to assess vitamin D status?

(2017) Daniel Bikle et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data

(2017) Adrian R Martineau et al.   BMJ-British Medical Journal

Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data

(2017) Adrian R Martineau et al.   BMJ-British Medical Journal

Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium

(2017) Martin Gaksch et al.   PLoS One

Hypercalcaemia-induced kidney injury caused by the vitamin D analogue calcitriol for psoriasis: a note of caution when prescribing topical treatment

(2016) E. Corden et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Vitamin D Daily short-term Supplementation does not Affect Glycemic Outcomes of Patients with Type 2 Diabetes

(2016) Stavri Chrysostomou   INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH

Efficacy of vitamin D replacement therapy on patients with chronic nonspecific widespread musculoskeletal pain with vitamin D deficiency

(2016) Ramazan Yilmaz et al.   International Journal of Rheumatic Diseases

Vitamin D 20 000 IU per Week for Five Years Does Not Prevent Progression From Prediabetes to Diabetes

(2016) Rolf Jorde et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial

(2016) A. Abbasnezhad et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Associations of total and free 25OHD and 1,25(OH)2D with serum markers of inflammation in older men

(2016) P. Srikanth et al.   OSTEOPOROSIS INTERNATIONAL

The immunomodulatory effect of vitamin D in chickens is dose-dependent and influenced by calcium and phosphorus levels

(2016) J. C. Rodriguez-Lecompte et al.   POULTRY SCIENCE

Effect of Cholecalciferol Supplementation on Vitamin D Status and Cathelicidin Levels in Sepsis

(2015) Sadeq A. Quraishi et al.   CRITICAL CARE MEDICINE

Modified-release oral calcifediol corrects vitamin D insufficiency with minimal CYP24A1 upregulation

(2015) Martin Petkovich et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mechanistic Effects of Calcitriol in Cancer Biology

(2015) Lorenza Díaz et al.   Nutrients

Novel method for real-time monitoring of ATP release reveals multiple phases of autocrine purinergic signalling during immune cell activation

(2014) C. Ledderose et al.   Acta Physiologica

Vitamin D Metabolism, Mechanism of Action, and Clinical Applications

(2014) Daniel D. Bikle   CHEMISTRY & BIOLOGY

Prospective Study of Vitamin D Status at Initiation of Care in Critically Ill Surgical Patients and Risk of 90-Day Mortality*

(2014) Sadeq A. Quraishi et al.   CRITICAL CARE MEDICINE

CYP24A1 Expression Inversely Correlates with Melanoma Progression: Clinic-Pathological Studies

(2014) Anna Brożyna et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Importance of Body Weight for the Dose Response Relationship of Oral Vitamin D Supplementation and Serum 25-Hydroxyvitamin D in Healthy Volunteers

(2014) John Paul Ekwaru et al.   PLoS One

Impact of vitamin D on immune function: lessons learned from genome-wide analysis

(2014) Rene F. Chun et al.   Frontiers in Physiology

Large, Single-Dose, Oral Vitamin D Supplementation in Adult Populations: A Systematic Review

(2013) Malcolm Kearns et al.   Endocrine Practice

Three-year follow-up of serum 25-hydroxyvitamin D, parathyroid hormone, and bone mineral density in nursing home residents who had received 12 months of daily bread fortification with 125 μg of vitamin D3

(2013) Veronica Mocanu et al.   Nutrition Journal

Association Between Preoperative 25-Hydroxyvitamin D Level and Hospital-Acquired Infections Following Roux-en-Y Gastric Bypass Surgery

(2013) Sadeq A. Quraishi et al.   JAMA Surgery

Vitamin D: Pharmacokinetics and Safety When Used in Conjunction with the Pharmaceutical Drugs Used in Cancer Patients: A Systematic Review

(2013) Deborah Kennedy et al.   Cancers

Inflammation and Oxidative Stress in Obesity, Metabolic Syndrome, and Diabetes

(2012) Pietro Galassetti   Experimental Diabetes Research

Vitamin D in the New Millennium

(2012) Sunil J. Wimalawansa   Current Osteoporosis Reports

Estimation of the dietary requirement for vitamin D in healthy adolescent white girls

(2011) K. D. Cashman et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Vitamin D: drug of the future. A new therapeutic approach

(2011) N. Gueli et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Megalin/Cubilin-mediated Uptake of FITC-labeled IgG by OK Kidney Epithelial Cells

(2011) Junya Nagai et al.   Drug Metabolism and Pharmacokinetics

Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline

(2011) Michael F. Holick et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Impact of Vitamin D on Regulatory T Cells

(2010) Emma S. Chambers et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Heterogeneity in Serum 25-Hydroxy-Vitamin D Response to Cholecalciferol in Elderly Women with Secondary Hyperparathyroidism and Vitamin D Deficiency

(2010) Andrea Giusti et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Serum 25-Hydroxyvitamin D and the Incidence of Acute Viral Respiratory Tract Infections in Healthy Adults

(2010) James R. Sabetta et al.   PLoS One

1,25-Dihydroxyvitamin D3 and IL-2 Combine to Inhibit T Cell Production of Inflammatory Cytokines and Promote Development of Regulatory T Cells Expressing CTLA-4 and FoxP3

(2009) L. E. Jeffery et al.   JOURNAL OF IMMUNOLOGY

Vitamin D Status: Measurement, Interpretation, and Clinical Application

(2008) Michael F. Holick   ANNALS OF EPIDEMIOLOGY

Vitamin D in Health and Disease

(2008) R. P. Heaney   Clinical Journal of the American Society of Nephrology

High-dose oral vitamin D3 supplementation in the elderly

(2008) C. J. Bacon et al.   OSTEOPOROSIS INTERNATIONAL