The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 13, Issue 7, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-07-28
DOI
10.1038/s41419-022-05115-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Iron homeostasis and disorders revisited in the sepsis
- (2021) Qinjie Liu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Ferroptosis: mechanisms, biology and role in disease
- (2021) Xuejun Jiang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Homeostatic regulation of STING by retrograde membrane traffic to the ER
- (2021) Kojiro Mukai et al. Nature Communications
- A compendium of kinetic modulatory profiles identifies ferroptosis regulators
- (2021) Megan Conlon et al. Nature Chemical Biology
- Necroptosis Underlies Hepatic Damage in a Piglet Model of Lipopolysaccharide-Induced Sepsis
- (2021) Qiao Xu et al. Frontiers in Immunology
- A myeloid–stromal niche and gp130 rescue in NOD2-driven Crohn’s disease
- (2021) Shikha Nayar et al. NATURE
- Integrated analysis of multimodal single-cell data
- (2021) Yuhan Hao et al. CELL
- Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells
- (2021) Liraz Shmuel-Galia et al. IMMUNITY
- STING-mediated Syk Signaling Attenuates Tumorigenesis of Colitis‑associated Colorectal Cancer Through Enhancing Intestinal Epithelium Pyroptosis
- (2021) Wenbin Gong et al. INFLAMMATORY BOWEL DISEASES
- Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C
- (2021) Ting-Ting Chu et al. NATURE
- Circulating mitochondrial DNA-triggered autophagy dysfunction via STING underlies sepsis-related acute lung injury
- (2021) Qinjie Liu et al. Cell Death & Disease
- STING1 Promotes Ferroptosis Through MFN1/2-Dependent Mitochondrial Fusion
- (2021) Changfeng Li et al. Frontiers in Cell and Developmental Biology
- STING-Mediated Interferon Induction by Herpes Simplex Virus 1 Requires the Protein Tyrosine Kinase Syk
- (2021) Chenyao Wang et al. mBio
- 20-HETE Participates in Intracerebral Hemorrhage-Induced Acute Injury by Promoting Cell Ferroptosis
- (2021) Ranran Han et al. Frontiers in Neurology
- Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis
- (2020) Lise Van Wyngene et al. EMBO Molecular Medicine
- Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study
- (2020) Kristina E Rudd et al. LANCET
- Structural Insights into STING Signaling
- (2020) Sabrina L. Ergun et al. TRENDS IN CELL BIOLOGY
- Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure
- (2020) Naoya Yamada et al. Cell Death & Disease
- Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death
- (2020) Changfeng Li et al. Autophagy
- IRF5 guides monocytes toward an inflammatory CD11c+ macrophage phenotype and promotes intestinal inflammation
- (2020) Alastair L. Corbin et al. Science Immunology
- Understanding human gut diseases at single-cell resolution
- (2020) Emilia Bigaeva et al. HUMAN MOLECULAR GENETICS
- Interferon-Independent Activities of Mammalian STING Mediate Antiviral Response and Tumor Immune Evasion
- (2020) Jianjun Wu et al. IMMUNITY
- Regulation and Consequences of cGAS Activation by Self-DNA
- (2020) Christian Zierhut et al. TRENDS IN CELL BIOLOGY
- Cathepsin B is a mediator of organelle-specific initiation of ferroptosis
- (2020) Feimei Kuang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Challenges and Opportunities of Deferoxamine Delivery for Treatment of Alzheimer’s Disease, Parkinson’s Disease, and Intracerebral Hemorrhage
- (2020) Amy Corbin Farr et al. MOLECULAR PHARMACEUTICS
- Lysosomal quality control of cell fate: a novel therapeutic target for human diseases
- (2020) Sheng-yu Zhu et al. Cell Death & Disease
- mtDNA-STING pathway promotes necroptosis-dependent enterocyte injury in intestinal ischemia reperfusion
- (2020) Xufei Zhang et al. Cell Death & Disease
- STING-dependent induction of lipid peroxidation mediates intestinal ischemia-reperfusion injury
- (2020) Jie Wu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Hepatic PPARα is critical in the metabolic adaptation to sepsis
- (2019) Réjane Paumelle et al. JOURNAL OF HEPATOLOGY
- Polymicrobial Bacteremia Involving Klebsiella pneumoniae in Patients with Complicated Intra-Abdominal Infections: Frequency, Co-Pathogens, Risk Factors, and Clinical Outcomes
- (2019) Qinjie Liu et al. Surgical Infections
- Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP
- (2019) Guijun Shang et al. NATURE
- Autophagy induction via STING trafficking is a primordial function of the cGAS pathway
- (2019) Xiang Gui et al. NATURE
- Deferoxamine mesylate in patients with intracerebral haemorrhage (i-DEF): a multicentre, randomised, placebo-controlled, double-blind phase 2 trial
- (2019) Magdy Selim et al. LANCET NEUROLOGY
- STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition
- (2019) Sabrina L. Ergun et al. CELL
- DAMPs and NETs in Sepsis
- (2019) Naomi-Liza Denning et al. Frontiers in Immunology
- Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis
- (2018) Rui Kang et al. Cell Host & Microbe
- UBXN3B positively regulates STING-mediated antiviral immune responses
- (2018) Long Yang et al. Nature Communications
- Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
- (2018) Gillian Dunphy et al. MOLECULAR CELL
- scFTD-seq: freeze-thaw lysis based, portable approach toward highly distributed single-cell 3′ mRNA profiling
- (2018) Burak Dura et al. NUCLEIC ACIDS RESEARCH
- The cytosolic sensor STING is required for intestinal homeostasis and control of inflammation
- (2017) M C C Canesso et al. Mucosal Immunology
- ALK is a therapeutic target for lethal sepsis
- (2017) Ling Zeng et al. Science Translational Medicine
- The Emerging Roles of STING in Bacterial Infections
- (2017) Fabio V. Marinho et al. TRENDS IN MICROBIOLOGY
- Signalling strength determines proapoptotic functions of STING
- (2017) Muhammet F. Gulen et al. Nature Communications
- The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
- (2016) Mervyn Singer et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- NF-κB transcriptional inhibition ameliorates cisplatin-induced acute kidney injury (AKI)
- (2016) Abdullah Ozkok et al. TOXICOLOGY LETTERS
- Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
- (2015) S. Liu et al. SCIENCE
- Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis
- (2015) Joseph D Mancias et al. eLife
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
- (2014) Joseph D. Mancias et al. NATURE
- GSVA: gene set variation analysis for microarray and RNA-Seq data
- (2013) Sonja Hänzelmann et al. BMC BIOINFORMATICS
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity
- (2012) Alexandra Kollara et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems
- (2012) Annika Reintam Blaser et al. INTENSIVE CARE MEDICINE
- Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity
- (2011) Huihui Chen et al. CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started